Lmst

CRAIG M CREWS boosted:

Leonard Hayflick (May 20, 1928 – August 1, 2024) , who discovered the cellular replication limit.

The serial cultivation of human diploid cell strains
https://www.sciencedirect.com/science/article/abs/pii/0014482761901926

CRAIG M CREWS boosted:

On this day in 1888: Selman A Waksman was born. He won 1952 #NobelPrize for his discovery of streptomycin #ThisDayInBiotech

A portrait of Selman A Waksman in a laboratory in front of laboratory equipment. He is wearing a laboratory coat, a light shirt and tie, glasses and a moustache.

CRAIG M CREWS boosted:

Interesting article about the amazing chemical proteomics research at Scripps Research. Chris Parker highlights the groundbreaking work in the field by e.g. Ben Cravatt and John Yates as well as some of the breakthroughs that his own lab has introduced. https://theanalyticalscientist.com/fields-applications/chemical-proteomics-realizing-therapeutic-potential

CRAIG M CREWS boosted:

A20: a jack of all trades https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(24)00031-X?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

CRAIG M CREWS boosted:

On this day in 2013: Frank Ruddle died, created 1st transgenic mouse, laid pathway for Human Genome Project http://whatisbiotechnology.org/index.php/people

CRAIG M CREWS boosted:

As previously mentioned, here's what Einstein had to say about segregation:

"There is a separation of white people and colored people in the United States. That separation is not a disease of colored people. It is a disease of white people. I do not intend to be quiet about it."

For the last 20 years of his career, Einstein declined almost all public speaking engagements, except those at Historically Black Colleges and Universities (HBCUs).

This photo was taken at Lincoln University, an HBCU.

Albert Einstein stands in front of a blackboard in a room full of Black men at Lincoln university, teaching a graduate class in physics.

CRAIG M CREWS boosted:

Online Now: Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)00093-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

CRAIG M CREWS boosted:

Online Now! Hallmarks of totipotent and pluripotent stem cell states https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(24)00039-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells

CRAIG M CREWS boosted:

Online Now: Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)00089-3?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

CRAIG M CREWS boosted:

Discovery of 6-Formylpyridyl Urea Derivatives as Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity https://covalentmodifiers.blogspot.com/2024/02/discovery-of-6-formylpyridyl-urea.html?utm_source=dlvr.it&utm_medium=mastodon

CRAIG M CREWS boosted:

AlphaFind: Discover structure similarity across the entire known proteome https://www.biorxiv.org/content/10.1101/2024.02.15.580465v1.full.pdf+html

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#proteomics #prot-preprint

CRAIG M CREWS boosted:

🚨Lipid Time🚨

Check our recent review! We delve into the role of Phosphoinositides, highlighting their function as molecular switches 🔛 across various biological processes and how their misregulation causes disease development!

@uniheidelberg
@HelsinkiUni
@freieuniversitaet

#lipidtime
#TRR186

https://www.jbc.org/article/S0021-9258(24)00133-9/fulltext#%20