This molecule doesn’t come from nature—and that’s exactly why it works. #Superbugs #AMR #NextGenAntibiotics
https://geekoo.news/the-lab-made-molecule-that-outsmarts-superbugs/
This molecule doesn’t come from nature—and that’s exactly why it works. #Superbugs #AMR #NextGenAntibiotics
https://geekoo.news/the-lab-made-molecule-that-outsmarts-superbugs/
Not per se a clinical trial but evidence points towards source control (surgery) being key in brain abscesses.
#IDSky #ClinMicro #AMR @cidjournal.bsky.social
academic.oup.com/cid/advance-...
Non-Operative versus Neurosurg...
What an inspiring quote re future use of host-directed therapies to treat infections:
"ID physicians will ... participate in immunophenotyping, ... offer immunoengineered solutions..., and take full advantage of the immune system to effect a cure without ... excessive immunopathology."
#IDSky #AMR
Immunotherapy for Infectious D...
🔽 antibiotic sales for livestock 👉 🔽 antibiotic resistance in livestock.
Livestock = an important, *modifiable* reservoir of #AMR
#IDSky #ClinMicro @bsacandjac.bsky.social
Decreasing antimicrobial resis...
Surge of Corynebacterium diphtheriae infection in reception centers for migrants in Europe beginning in summer of 2022.
Important to define these strains, including their antibiotic susceptibility (or lack of), to enable appropriate treatment. #IDSky #AMR #MedSky
www.nejm.org/doi/full/10....
Corynebacterium diphtheriae Ou...
If interested, this is the primary paper for this BBC news article
#IDSky #ClinMicro #AMR
(2/2)
www.journalofinfection.com/article/S016...
Faecal microbiota transplant t...
Poo pills - perhaps not the alluring treatment name, but gets the message across!
#IDSky #ClinMIcro #AMR
(1/2)
Doctors use poo pills to flush...
Part 3 of our #AMR series: What can we do to help prevent Antimicrobial Resistance?
👉🏾Take antibiotics only when prescribed
👉🏾Don’t share antibiotics
👉🏾Practice hand hygiene
👉🏾Stay vaccinated
Animation by: Mitchel Gilbert Messina
Important finding. Widespread antibiotic use, with best intentions, has long term #AMR consequences.
"Azithromycin MDA is associated with macrolide resistance that persists and potentially spreads to untreated populations."
#IDSky #ClinMicro #MedSky @thelancetinfdis.bsky.social
Long-term effects of azithromy...
Im Kampf gegen #Antibiotikaresistenzen werden dringend Wirkstoffe mit neuartigem Wirkmechanismus benötigt. Die Substanz #Saarvienin A, die Forscher:innen vom @helmholtz_hips & @univienna entdeckt haben, ist ein vielversprechender Kandidat dafür. #AMR
https://www.helmholtz-hzi.de/media-center/newsroom/news-detailseite/forschende-entdecken-ersten-saar-wirkstoff/
AMR, hedefe bir yılda ulaştı: Üretimden satışlarla listenin 113’üncü sırasında yer alan AMR, sektöründe de hem büyüklük hem ihracat açısından üçüncü oldu
Türkiye’nin seçkin altın rafinerilerinden biri olan Aleks Metal Rafineri (AMR), son teknoloji ürünü makinelerle faaliyete başladığı 2024 yılındaki üretimden satışları ile en büyük sanayi kuruluşları arasına girmeyi başardı.… https://www.eshahaber.com.tr/haber/amr-hedefe-bir-yilda-ulasti-228747.html?utm_source=dlvr.it&utm_medium=mastodon EshaHaber.com.tr #AMR #AleksMetalRafineri #Türkiye500BüyükSanayiKuruluşu #ihracat #üretim
So long. Probably too long.
#IDSky #ClinMicro #AMR
RE: https://bsky.app/profile/did:plc:6peijvvlgjki2rrxitoa65sv/post/3lpwegcf4we2j
PART 1: What is AMR? 💡Did you know that 39 trillion microbes live in and on our bodies? Most keep us healthy, but some cause infections. Enter antimicrobials. However, bacteria are evolving and becoming resistant to these medicines. We call this #AMR.
Animator: Mitchell Gilbert Messina
Last talk is from Stephanie Myers on chemical approaches to combating #AMR ending a fantastic #ChemBioWomenNE
Reaching consensus definitions on diseases is hard.
Exemplified here by complicated urinary tract infections in @thelancetinfdis.bsky.social
Important implications:
- how to test new antibiotics?
- is current definition correct?
#IDSky #ClinMicro #AMR #UTISky
www.thelancet.com/journals/lan...
Consensus position statement o...
Did not know this was a thing (even if rare)
Tigecycline-induced hypoglycaemia
#IDSky #ClinMicro #AMR @jac-amr.bsky.social
academic.oup.com/jacamr/artic...
Incidence, characteristics and...
Africa: How Germs Outsmart Antimicrobials and Why It's Making Us Sicker: [IPS] Bulawayo -- More people are dying from once treatable infections because the medicines we rely on are no longer working as they should. The culprit? A growing health threat called antimicrobial resistance (AMR). http://newsfeed.facilit8.network/TKtBdj #AntimicrobialResistance #AMR #InfectiousDiseases #GlobalHealth #PublicHealth
This is helpful, opening up a new drug (tigecycline) to be put into elastomeric devices for patients that need #OPAT #IDSky #ClinMicro #AMR @jac-amr.bsky.social academic.oup.com/jac...
#Phages (viruses that kill bacteria) are considered a potential approach to combat multidrug-resistant pathogens. However, they don't always deliver the desired results on their own. A research team at #CharitéBerlin has now demonstrated that combining phages with an antibiotic is much more effective, at least in the lab, against a form of #pneumonia caused by multidrug-resistant bacteria 💪👩🔬.
#CharitéPaper #medicine #science #research #MedMastodon #AMR #antibiotics
#Phagen – also Viren, die Bakterien abtöten – sind ein möglicher Ansatz gegen multiresistente Erreger. Sie allein zeigen aber nicht immer die erhoffte Wirkung. Ein Forschungsteam der #CharitéBerlin belegt jetzt: Kombiniert man Phagen mit einem Antibiotikum, hilft das im Labor viel besser gegen eine Form der Lungenentzündung mit multiresistenten Bakterien 💪👩🔬. Mehr zu der Kombitherapie:
#CharitéPaper #Medizin #Forschung #Wissenschaft #MedMastodon #Medibubble #AMR