Lmst

#spotLights hits episode 10! 🙌

Jonathan Townson talks to Helena Crellin (#BuckleyLab) about her #preprint introducing an optogenetic approach to study "how forces are propagated through complex tissues during development" in #zebrafish 🧠🐟

Listen below! 🎧
🎙️ https://youtu.be/6uce4whDt2M

#biologists100 #optogenetics #OpenScience #podcast

THE EXPERT EDGE BY ZPONZ: Expert in Optogenetics
Aryn Gittis received her Ph.D. from UCSD in 2008 where she studied the vestibular system in the lab of Sascha du Lac. From 2008-2012 she was a postdoc with Anatol Kreitzer at the Gladstone Institute/UCSF where she began her studies of basal ganglia circuitry and its plasticity in disease.
#ZPONZ #GetPaidForExpertise #MonetizeYourSkills #Optogenetics

🚀 What role does protein design play in advancing next-gen optogenetic tools?

🔗 Protein design accelerates the development and application of optogenetic tools. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.014

📚 CSBJ: https://www.csbj.org/

#Optogenetics #ProteinEngineering #Neuroscience #AlphaFold #ProteinDesign #SyntheticBiology

Protein design accelerates the development and application of optogenetic tools. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.014

New #preLights post from Vibha Singh! 👀

In this highlighted #preprint, the research team (#NalbantLab) introduces a powerful new approach to studying mechanobiological regulation in cancer. In doing so, they describe how tumour cells manage to “pull” themselves away from the tumour bulk during invasion.

Read the #preLight here 👉 https://prelights.biologists.com/highlights/optogenetic-stimulation-of-lbc-gef-mediated-rho-activity-dynamics-promotes-cell-invasion/

#CancerResearch #Optogenetics #Mechanobiology #TumourInvasion

#Optogenetics is a technique that uses light to control cells, including neurons. It combines genetics and optics to achieve precise control over the activity of specific cells.

https://knowledgezone.co.in/trends/browser?topic=Optogenetics

(09 Apr) Fruit flies can be made to act like miniature robots

Light and smells can turn flies into remote-controlled near-automatons.

https://s.faithcollapsing.com/zt6e9
Archive: ais: https://archive.md/wip/aonCp ia: https://s.faithcollapsing.com/3jisv

#biology #fruit-flies #neurobiology #optogenetics #robotics #science

A fruit fly on a white background, with red eyes, a grey body, and dark stripes.

How do we acquire aversions against flavors of food that causes malaise long after we have experienced the flavors? #Optogenetics in mice reveals a new mechanism for delayed association. https://www.nature.com/articles/s41586-025-08828-z

From Europe, with love for science. #ELEANOR: Studying the brain's complexity with light on a chip https://www.ru.nl/en/donders-institute/news/eleanor-studying-the-brains-complexity-with-light-on-a-chip #BCI #NeuroTech #photonics #optogenetics #neuroscience

Seeing certain things (spiders, ...) leads to instinctive #fear reactions. Animals can learn to overcome such reactions. This study used #optogenetics to identify the relevant brain areas in mice. Could be useful for development of treatments. https://www.science.org/doi/10.1126/science.adr2247

Cortical circuits for cross-modal generalization (in mice) https://www.biorxiv.org/content/10.1101/2023.10.13.562215v4 "Optogenetic sensory substitution for cross-modal generalization"; #optogenetics #crossmodal #neuroscience