Lmst

DARPA's "Generative Optogenetics" Program Is All That We've Feared & Held Hostage By Geoengineering https://www.thelastamericanvagabond.com/darpa-optogenetics-geoengineering/ #TheDailyWrapUp #DARPA #Optogenetics #Magnetogenetics #Geoengineering

#Zhongmou wins U.S. #FDA clearance for China's first optogenetic human trials www.linkedin.com/pulse/zhongm... using ZM-02 for treating advanced retinitis pigmentosa; #RP #blindness #opsin #optogenetics #PRISM

Zhongmou Wins U.S. FDA Clearan...

#Zhongmou wins U.S. #FDA clearance for China's first optogenetic human trials https://www.linkedin.com/pulse/zhongmou-wins-us-fda-clearance-chinas-first-optogenetic-k1vte/ using ZM-02 for treating advanced retinitis pigmentosa; #RP #blindness #opsin #optogenetics #PRISM

"By bypassing damaged rod and cones, this mutation-agonistic approach is being developed for advanced retinal diseases, including retinitis pigmentosa and geographic atrophy (GA) in age-related macular degeneration."

Advantages of human opsins in optogenetic visual restoration https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1725264/full #optogenetics #BCI #NeuroTech

Advantages of human opsins in optogenetic visual restoration www.frontiersin.org/journals/neu... #optogenetics #BCI #NeuroTech

Frontiers | Advantages of huma...

Adam Claridge-Chang and Shiqiang Gao analyse K+ channelrhodopsins:

"both the absolute K+ to Na+ permeability ratio and its stability over time determine the inhibition to activation transition, which limits their utility for silencing neural circuits."

And they found that a single aminoacid mutant, KCR1-C29D, "shows a relatively high and the most stable K+ to Na+ permeability ratio during illumination", better than heavily protein engineered versions.

"Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins", Duan et al. 2025
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509180

#neuroscience #optogenetics #channelrhodopsin

Bloomberg: Engineered protein that responds to light could help restore sight www.bloomberg.com/news/newslet... Archived at archive.ph/46Olz #optogenetics

Engineered Protein That Respon...

Bloomberg: Engineered protein that responds to light could help restore sight https://www.bloomberg.com/news/newsletters/2025-10-07/engineered-protein-that-responds-to-light-could-help-restore-sight Archived at https://archive.ph/46Olz #optogenetics

@seeingwithsound

It's interesting that uses of optogenetic therapies work well with goggles that translate RGB video input to "retinal codes" that are projected in the frequency range and amplitudes appropriate for the light sensitive rhodopsins. Fascinating.

#optogenetics #blind #rp #retinituspigmentosa #goggles #vr #ar

The optimism of #optogenetics https://ophthalmologymanagement.com/issues/2025/julyaugust/the-optimism-of-optogenics/ "Vision rehabilitation: Patients receiving optogenetic therapy need training to interpret new visual signals, which requires specialized rehabilitation protocols." #blindness #RP

The optimism of #optogenetics ophthalmologymanagement.com/issues/2025/... "Vision rehabilitation: Patients receiving optogenetic therapy need training to interpret new visual signals, which requires specialized rehabilitation protocols." #blindness #RP

The Optimism of Optogenetics

(YouTube) Engineering ambient light-sensitive opsins for #optogenetics https://www.youtube.com/watch?v=ptPSW4sOnjk

(YouTube) Engineering ambient light-sensitive opsins for #optogenetics www.youtube.com/watch?v=ptPS... by @science.xyz

Engineering Ambient Light-Sens...

(YouTube, Chinese w/o captions but graphical English subtitles) Blind patient treated with ZM-02 optogenetic gene therapy https://www.youtube.com/watch?v=4kFOhopQZFo Zhongmou Therapeutics; #RP #blindness #optogenetics

(YouTube, Chinese w/o captions but graphical English subtitles) Blind patient treated with ZM-02 optogenetic gene therapy www.youtube.com/watch?v=4kFO... Zhongmou Therapeutics; #RP #blindness #optogenetics

Hear our patient treated with ...

THE EXPERT EDGE BY ZPONZ: Expert in Optogenetics
Annabelle Singer is an Assistant Professor in the Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. The central goal of Dr. Singer’s research program is to understand how neural activity produces memories and spurs the brain’s immune system.
#ZPONZ #GetPaidForExpertise #MonetizeYourSkills #Optogenetics

THE EXPERT EDGE BY ZPONZ: Expert in Optogenetics
Aryn Gittis received her Ph.D. from UCSD in 2008 where she studied the vestibular system in the lab of Sascha du Lac. From 2008-2012 she was a postdoc with Anatol Kreitzer at the Gladstone Institute/UCSF where she began her studies of basal ganglia circuitry and its plasticity in disease
#ZPONZ #GetPaidForExpertise #MonetizeYourSkills #Optogenetics

Multisensory integration, brain plasticity and optogenetics in visual rehabilitation https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1590305/full

"In the context of visual rehabilitation, combining pharmacological agents with multisensory training paradigms, such as audio-visual integration or tactile-visual substitution, could accelerate recovery by fostering neuroplasticity."

#BCI #optogenetics #multisensory #crossmodal #pharmacology #neuroplasticity #VR