New from the Brady Lab at Rockefeller University: Environmental resistome–guided development of resistance-tolerant antibiotics | PNAS

Congrats to lead author Dr. James Peek! In this paper, we propose using the existing reservoir of resistance genes/mechanisms in the environment (the "resistome") as an early warning system for antibiotic resistance in the clinic.

https://www.pnas.org/doi/10.1073/pnas.2504781122

#antibiotics #antibioticresistance #naturalproducts #resistome #drugdiscovery #metagenomics

Spatio-temporal variation of the #microbiome and #resistome repertoire along an anthropogenically dynamic segment of the Ganges River, India - PubMed

https://pubmed.ncbi.nlm.nih.gov/36773904/?utm_source=dlvr.it&utm_medium=twitter&utm_campaign=None&utm_content=14a2MZa9gZvaIYpuKMGRaHSk2Y8ZtyEVUJR7eXJdAWXeik7g7S&fc=None&ff=20230212085141&v=2.17.9.post6%2086293ac

The global distribution and environmental drivers of the soil antibiotic resistome

In a new paper https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-022-01405-w in Microbiome, Manuel Delgado-Baquerizo et al. analyze 285 antibiotic resistance genes (ARGs) in soils from 1012 sites across all continents and created the first global atlas with the distributions of topsoil ARGs. This work sets the foundations for understanding the ecology and global distribution of the environmental soil antibiotic resistome. #Resistome #ARGs

#Microbiome, #resistome and #mobilome of chlorine-free drinking #water treatment systems | bioRxiv

https://www.biorxiv.org/content/10.1101/2022.12.08.519565v1

Single-cell tools give insight into active antibiotic resistome in soils https://www.eurekalert.org/news-releases/966562 don't think I've come across #resistome before #omics