#UKBiobank

Andreas BeckerCaramba1
2026-01-04

9.500 Datensätze trainieren neues medizinisches Modell.

CardioKG nutzt einen Wissensgraphen, um MRT-Bilddaten strukturell mit Genetik zu matchen. Das Ziel ist Drug Repurposing: Rheuma-Mittel werden basierend auf visuellen Merkmalen gegen Herzinsuffizienz identifiziert. Das senkt Entwicklungszyklen drastisch.

Ist Korrelation in Datenbanken gut genug für eine ärztliche Verschreibung?
all-ai.de/news/news26/ki-herz-

2025-08-29

"A large federally-funded study coming out of [US]America, published in Nature, 'marijuana users have enhanced cognitive abilities' ... [they] analysed brain imaging and cognitive data, from 37929 people. The cannabis consumers consistently outperformed the non-users in the cognitive tests. They had brain network characteristics typically associated with younger brains."

#ChrisFowlie, 2025

95bfm.com/bcast/95bfm-drive-w-

#podcasts #95bFM #MarijuanaMedia #UKBioBank #cannabis #cognition #research

2025-08-19

Respiratory viruses may trigger dormant cancers

August 19, 2025 At a Glance A study in mice showed how common respiratory viruses may awaken dormant…
#NewsBeep #News #Headlines #Breastcancer #dormantdisseminatedcancercells #FlatironHealth #IL-6 #immunoediting #influenzavirus #interleukin-6dependent #JamesDeGregori #Latvia #LV #metastasis #nature #SARS-CoV-2 #UKBiobank
newsbeep.com/70275/

Pierre Lindenbaumyokofakun@genomic.social
2025-05-07

I've been told that in the UKBB bgen files , the order of the alleles is ALT-first, REF-second.

1) can you confirm this ?
2) WWWWHYYYYYYYYYYYYYYY ?

#ukbiobank #bgen #bioinformatics

2024-11-22

Did you know you can access (if provided by authors, please do!) COHORT information?
www.ebi.ac.uk/gwas/ -> Download -> Files -> Studies. As shown in the figure,
#UKBiobank is the biggest contributor!

Gen-ethisches Netzwerk e.V.genetzwerk@systemli.social
2024-10-30

Die #UKBiobank ist eine öffentlich finanzierte Forschungsdatenbank in Großbritannien: sie verknüpft die #DNA-Daten von 500.000 Brit*innen mit Daten zu Verhalten, sozialem Status und Gesundheit – eigentlich soll sie dazu dienen Krankheitsursachen zu ergründen und Therapien zu entwickeln. (2/5)

Bastian Greshake Tzovarasgedankenstuecke@scholar.social
2024-10-26

In light of the latest "race science" genetics thing, I've taken some time to expand the #Wikipedia article on #UKBiobank - to collect some of the criticisms that have been raised over the years but that seemed quite absent.

en.wikipedia.org/wiki/UK_Bioba

@alesssia @mbaudis @marcrr Let me know if I missed something!

(Also see the diff at en.wikipedia.org/w/index.php?t)

Marc Robinson-Rechavimarcrr@ecoevo.social
2024-10-26

@gedankenstuecke @gvwilson I went back to Xitter to screenshot what I wrote about those at the time. #UKBiobank

Tweets from August 2019:
I've been reading the comments on the homosexuality GWAS, which are much more interesting to me than the paper, and one point regarding consent just jumped out of the screen at me.

For @uk_biobank, the broad consent is to "improve the prevention, diagnosis and treatment of illness and the promotion of health".
How the hell can this study be justified under such a consent agreement?
https://broadinstitute.org/blog/opinion-seeking-justice-age-genomics-and-call-higher-ethical-standards-research-involving-humanTweets from August 2019:

I went to check the consent form, in case the opinion was a simplification. No. It's exactly that. At every page, the consent forms speak about health and medical research.
https://ukbiobank.ac.uk/consent
https://ukbiobank.ac.uk/participant-information-leaflet

So either homosexuality is estimated by the scientists and administrators involved to be an illness, and WTF, or just WTF?
Lazarou Monkey Terror 🚀💙🌈Lazarou
2024-10-17

Creepy tech bros and their desire to create a world of all-white Daughter-wives....

Someone white and male no doubt thought giving these creeps our sensitive data was in the Public interest. I think this person needs to explain themselves, whether they were tricked or not.

theguardian.com/world/2024/oct

Benjamin Carr, Ph.D. 👨🏻‍💻🧬BenjaminHCCarr@hachyderm.io
2024-05-20

#Proteins in #blood could provide early #cancer warning ‘by more than seven years’
Proteins in the blood could warn people of cancer more than seven years before it is diagnosed. #Scientists at the University of Oxford studied blood samples from more than 44,000 people in the #UKBiobank, including over 4,900 people who subsequently had a cancer diagnosis.
Study identifies 618 proteins linked to 19 types of cancer, which could lead to much earlier detection
theguardian.com/society/articl

Pierre Lindenbaumyokofakun@genomic.social
2024-03-11

asking for AntoineRimbert@twitter twitter.com/AntoineRimbert/sta "I've been searching around for a file defining: "pvcf_blocks" in UKB-RAP for the pVCF 500k WGS. We did not get any answer from the community forum. Any help would be highly appreciated !" #ukbiobank

Pierre Lindenbaumyokofakun@genomic.social
2024-02-20

afb.ukbiobank.ac.uk/ "The UK Biobank Allele Frequency Browser is a resource of variant allele frequencies and is being made publicly available." #ukbiobank #genetics #genomics

2024-02-11

I have worked on a lot of papers, this is my first preprint.

Analyzing large biobanks of genomic data requires a fresh look at our quality control metrics, especially as we move to NGS and more diverse populations.

You may be throwing out biologically important variants.

I would be happy to hear feedback.

#UKBiobank #HardyWeinbergEquilibrum
#statistics #statisticalgenetics #GWAS #genetics #preprint

medrxiv.org/content/10.1101/20

2023-11-12

#UKBiobank, a large scale #health monitoring project has been sharing detailed medical data collected from 500,000 volunteers, with commercial organisations including insurance companies and financial service providers WITHOUT CONSENT.

Despite public statements it would not do this, it is hiding behind a change in policy that was vague and which cannot constitute informed choice and consent.

The #ICO will likely do nothing as usual.

theguardian.com/technology/202
#health #privacy #GDPR

2023-11-12

Sensitive health information donated for medical research by half a million UK citizens has been shared with insurance companies despite a pledge that it would not be.
UK Biobank opened up its vast biomedical database to insurance sector firms several times between 2020 and 2023. The data was provided to insurance consultancy and tech firms.

We predicted this would happen. This is why Palantir wants to get its hands on #NHS data.
#UKBiobank #Privacy #Data
theguardian.com/technology/202

Pierre Lindenbaumyokofakun@genomic.social
2023-11-01

"we are delighted to announce the release of #gnomAD v4, which includes data from 807,103 total individuals. This release is nearly 5x larger than the combined v2/v3 (...) including 416,555 individuals from the #UKBiobank" gnomad.broadinstitute.org/news #genetics #genomics

2023-07-04

RT @: @chrisdwhelan presenting on the transformative potential of #proteomics in #UKBiobank for accelerated genetic targets and better treatment options for #health find out about the project here: ukbiobank.ac.uk/learn-more-abo

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