🧩 Could structural AI finally decode the complex language of T-cell antigen recognition?

🔗 STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ProteinLanguageModels #Immunotherapy #ComputationalBiology #Bioinformatics #MachineLearning #Immunology #ProteinEngineering #TCR #HLA #DrugDiscovery #AI

Groundbreaking research reveals how targeting DNA repair pathways could revolutionize cancer immunotherapy, offering new hope for more effective treatment strategies. #Cancer #Immunotherapy

🚀 Groundbreaking study in Nature: 7/10 people with HIV achieved ART-free control via combo immunotherapy—vaccination, bNAbs & latency reversal! CD8+ T cells key to curbing rebound. Hope for HIV cure? https://www.nature.com/articles/s41586-025-09929-5 #HIVResearch #Immunotherapy #Science #Newz

New Cancer Treatment Seeks Out Deadly Tumors And Eliminates Them https://onlinemarketingscoops.com/2025/12/03/new-cancer-treatment/
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#cancer #treatment #chemotherapy #immunesystem #immunotherapy #disease #medicalnews #oncology #fightcancer #tumors

Creative Biolabs revolutionizes CAR-T therapy development with comprehensive CDMO solutions, bridging scientific discovery and clinical innovation through advanced genetic engineering and manufacturing expertise. #Immunotherapy #MedicalInnovation

Nose drops based on nano-technology can deliver drugs to the brain without the need for invasive surgery. The approach has been tested on mice and opens a new direction for brain cancer immunotherapy. See http://www.neat-news.com/3470.php. #nose_drops #immunotherapy #brain_cancer

Alfa Cytology launches revolutionary ETES platform: Precision T-cell engagement technology promises targeted cancer treatment with minimal systemic toxicity. Advanced immunotherapy breakthrough for personalized oncology research. #Immunotherapy #Cancer

Why are tumor vaccines not more effective? This preprint points to dosage: more boosts, better results. But can the body tolerate that, and would the FDA allow it?

#mRNA
#tumor
#immunotherapy
#immunology
#science

https://www.biorxiv.org/content/10.1101/2025.11.16.687774v1-0

With a five-year survival rate of less than 5%, #glioblastoma is one of the most aggressive types of #brain #cancer. Until now, all available treatments, including #immunotherapy — which involves strengthening the immune system to fight cancer— have proved disappointing
#Immunology #Oncology #sflorg
https://www.sflorg.com/2025/11/ongy11202501.html

As the saying goes, one man’s trash is another man’s treasure: the flow-cytometry doublets that are routinely excluded from analysis are in fact a rich source of tumor-reactive T cells.

#immunology
#science
#tumor
#immunotherapy

https://www.nature.com/articles/s41586-025-09754-w

🎉 Congratulatons to Li Tang, head of the @EPFL Laboratory of Biomaterials for Immunoengineering: He has just been awarded the 2025 #LemPrize by the Wrocław University of Science and Technology for his groundbreaking work on #cancer #immunotherapy!

🔗 https://actu.epfl.ch/news/li-tang-wins-lem-prize/

Notable observation.

"Although Ms4a7−/− mice showed normal cDC1 development and turnover, they failed to prime antigen-specific CD8+ T cells following infection or tumor development. "

#immunology
#science
#cancer
#immunotherapy

https://www.science.org/doi/10.1126/science.ady5362

🧬 Cancer vaccines aren’t science fiction anymore, they’re reshaping treatment in 2025.

From mRNA breakthroughs to personalized therapies, cancer vaccines are changing how doctors fight cancer. Our latest guide explores how these innovations are improving survival, reducing relapse, and offering new hope to patients and families.

Explore more👉 https://blog.banishcancer.org/updates-on-cancer-vaccines-progress-and-perspectives-2025/

#CancerVaccines #Oncology #Immunotherapy #PersonalizedMedicine #MRNA #BanishCancer

There’s growing talk that personalized cancer medicine is the future usually meaning individualized #cancer #immunotherapy using mRNA or peptide #vaccines. But before that vision makes sense, some key questions about what cancer suppression really is must be clarified.

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IMMUNIA, hệ thống AI kết hợp GPT-4o, GPT-5, và Gemini 2.5 Pro, đã phát hiện gene mới (PTPRS, VCAN, MXRA5) cho điều trị miễn dịch chính xác. Mở đường cho AI trong nghiên cứu y sinh. #AI #Immunotherapy #Yhọc #PrecisionMedicine

https://www.reddit.com/r/singularity/comments/1orbtqn/immunia_a_multillm_reasoning_agent_for/

"Here, we report our finding that manganese ion (Mn2+) potentiates various TLR agonists, leading to robust activation of the TLR pathway"

#TLR
#tumor
#adjuvants
#immunotherapy

https://www.pnas.org/doi/10.1073/pnas.2409559121

MIT and Harvard researchers engineer enhanced natural killer cells, potentially revolutionizing cancer immunotherapy with breakthrough cell modification technique that improves tumor targeting and reduces immune rejection #CancerResearch #Immunotherapy

Lifordi Immunotherapeutics advances targeted glucocorticoid therapy for rheumatoid arthritis with breakthrough antibody-drug conjugate LFD-200, showing promising nonclinical results #Immunotherapy #Rheumatology

New Weapon Against Breast Cancer. A new, supercharged form of immunotherapy for breast cancer has just been announced by UCLA oncologists. #immunotherapy #CARNKT #cancer #breast #triplenegative #ovarian #pancreatic #lung
https://www.instagram.com/p/DQdod3Mj3HW/

CAR NK cell therapy clinical trial puts follicular lymphoma survivor into remission

When JC Cox was diagnosed with a type of non-H…
#NewsBeep #News #Headlines #B-CellLymphoma #CARNK-cellsResearch #caregivers #ClinicalTrials #FamilyFriends #FollicularLymphoma #immunotherapy #Latvia #LV #lymphoma #LymphomaandMyeloma #Non-HodgkinLymphoma #Patient&CaregiverStories #patients #StemCellTransplantationandCellularTherapy #StemCellTransplantationCellularTherapy #survivors
https://www.newsbeep.com/216340/