#pathogenesis

2025-06-27

New publication: Experimental Usutu virus infection in Eurasian blackbirds. #turdusmerula #onehealth #pathogenesis #usutuvirus
doi.org/10.1038/s44298-025-001

Figure 7 in Agliani et al. (2025): "Eight Eurasian blackbirds were sampled on day -7 (blood, serum, pharynx and cloacal swabs and breast feathers); after sampling, the blackbirds were singularly housed in cages in isolators and left to acclimatize for 7 days and activity and health status were monitored. On day 0, blackbirds were either inoculated with USUV Afr3 (n = 3), Eu3 (n = 3), or sterile PBS (n = 2). On 1, 3 and 5 days post inoculation (d.p.i.) blackbirds were sampled (blood, serum, pharynx and cloacal swabs and breast feathers). At the humane endpoint, blackbirds were euthanized, necropsied, and tissue samples were collected for histopathology, tissue titration and RT-qPCR. Created in BioRender, agreement licence number OO28BUTARJ."
Giuseppe MichieliGMIK69@mstdn.science
2025-06-21
Giuseppe MichieliGMIK69@mstdn.science
2025-05-12

#Pathogenesis Induced by #Influenza Virus #Infection: Role of the Early Events of the Infection and the Innate Immune Response, etidiohnew.blogspot.com/2025/0

Giuseppe MichieliGMIK69@mstdn.science
2025-04-16

Subacute Sclerosing #Panencephalitis: Recent #Advances in #Pathogenesis, #Diagnosis, and #Treatment pubmed.ncbi.nlm.nih.gov/402350

SSPE is invariably #fatal. Notably, reports of prolonged survival and disease stabilization have been documented, particularly with early and combined therapy.

2025-01-27

The #information #society 2.0 - We inform us to death

For this purpose, in the 1st part of the whole text a #media-theoretical #diagnosis, in the 2nd part a media-theoretical #pathogenesis and in the last part a media-theoretical #treatment #plan shall be established. So first, let's start with the diagnosis.

"Hiding things in your room."

More at: philosophies.de/index.php/2021

The #information #society 2.0 - We inform us to death
2025-01-24

The #information #society 2.0 - We inform us to death

For this purpose, in the 1st part of the whole text a #media-theoretical #diagnosis, in the 2nd part a media-theoretical #pathogenesis and in the last part a media-theoretical #treatment #plan shall be established. So first, let's start with the diagnosis.

"Hiding things in your room."

More at: philosophies.de/index.php/2021

The #information #society 2.0 - We inform us to death
2025-01-14

The #information #society 2.0 - We inform us to death

The #pathogenesis

This #excess of #information, the "information #overload / #surge" caused by the supposed news or rather #entertainment #programs has led to the term of the so-called "information society", which was coined by the US-American sociologist Daniel #Bell in his book "The Coming of Post-Industrial Society" (1973).

More at: philosophies.de/index.php/2021

The #information #society 2.0 - We inform us to death

The #pathogenesis
2025-01-13

The #information #society 2.0 - We inform us to death

For this purpose, in the 1st part of the whole text a #media-theoretical #diagnosis, in the 2nd part a media-theoretical #pathogenesis and in the last part a media-theoretical #treatment #plan shall be established. So first, let's start with the diagnosis.

"Hiding things in your room."

More at: philosophies.de/index.php/2021

The #information #society 2.0 - We inform us to death
Giuseppe MichieliGMIK69@mstdn.science
2024-12-31
Giuseppe MichieliGMIK69@mstdn.science
2024-11-21

#Age-Dependent #Pathogenesis of #Influenza A Virus #H7N9 Mediated Through #PB1-F2-Induced Mitochondrial DNA Release and Activation of cGAS-STING-NF-κB Signaling

Source: Journal of Medical Virology, ABSTRACTExactly why human infection of avian influenza A virus H7N9 causes more severe disease in the elderly remains elusive. In this study, we found that H7N9 PB1-F2 is a pathogenic factor in 15–18-month-old BALB/C mice (aged mice) but not in 6–8-week-old young adult mice…

etidioh.wordpress.com/2024/11/

Giuseppe MichieliGMIK69@mstdn.science
2024-10-30

A systematic #review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America

Source: Proceedings of the Royal Society Biological Sciences, AbstractThe lack of consolidated information regarding the response of wild bird species to infection with avian influenza virus (AIV) is a challenge to both conservation managers and researchers alike, with related sectors also impacted, such as public health and…

etidioh.wordpress.com/2024/10/

Giuseppe MichieliGMIK69@mstdn.science
2024-09-04

A systematic #[review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America, BioRxIV: biorxiv.org/content/10.1101/20

This study represents the first comprehensive effort to compile available literature regarding the pathobiology of AIV's in all wild birds in over a decade. This database provides an opportunity to critically examine and assess what is known and identify where further insight is needed.

Zeitgeisty Aphorismszeitgeisty
2024-08-17

dies when is born.

Giuseppe MichieliGMIK69@mstdn.science
2024-08-06

What The #Pox? #Review of #Poxviruses Affecting #Humans, J Clin Virol.: sciencedirect.com/science/arti

This review examines various poxviruses affecting humans, with discussion of less commonly encountered Poxviridae members, including #pathogenesis, #epidemiology, and #diagnostic methods. Poxvirus #treatment is beyond the intended scope of this review and will not be discussed.

Giuseppe MichieliGMIK69@mstdn.science
2024-07-25

@Infoseepage Here another proof of what you're saying: #Pathogenesis of #H5N1 #Influenza Virus Infections in #Mice & #Ferret Models Differs According to #Respiratory Tract or #Digestive System Exposure, J Infect Dis.: academic.oup.com/jid/article/1

Our results demonstrated that exposure of digestive system to H5N1 influenza viruses could initiate infection either through the #tonsil, with spread to respiratory tissues, or through #intestinal infection, with spread to the liver and #pancreas.

Giuseppe MichieliGMIK69@mstdn.science
2024-06-28

An ex vivo #human precision-cut #lung slice #platform provides insight into #SARS-CoV-2 #pathogenesis and #antiviral drug #efficacy, J Virol.: journals.asm.org/doi/full/10.1

We identified early induction of specific #cytokines, especially IP-10 and IL-8, as potential predictors for severe #COVID19, & uncovered a hitherto unrecognized phenomenon that while infectious virus disappears at late times of infection, viral #RNA persists and lung histopathology commences.

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