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Early clinical trial supports MASL as a targeted oral cancer treatment

Rowan University and Sentrimed®, a clinical-stage biopharmaceutical company focused on developing safer, orally dosed oncology the…
#NewsBeep #News #Headlines #Biopharmaceutical #Cancer #Carcinoma #CellProliferation #Cell] #ClinicalTrial #Glycoprotein #Latvia #LV #Malignant #Medicine #Mortality #Oncology #OralCancer #Proliferation #Receptor #Research #SquamousCellCarcinoma #Therapeutics #tumor
https://www.newsbeep.com/49394/

#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @PLOSBiology https://plos.io/3HP2obF

Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

A replicating recombinant vesicular stomatitis virus #model for dairy #cattle #H5N1 #influenza virus #glycoprotein #evolution, https://etidiohnew.blogspot.com/2025/06/a-replicating-recombinant-vesicular.html

In our latest interesting fact about #glycans we take a look at the most abundant #glycoprotein found in #urine, and how its glycosylation and function varies under different genetic physiological conditions.

#glycotime #uromodulin

In this month's interesting facts about #glycans we look at the #glycoprotein collagen and its unique #glycosylation

Read the post: https://research.bidmc.org/ncfg/blog/facts-about-collagen-and-its-glycosylation-one-most-common-glycoproteins-all-animals

For more interesting facts check: https://research.bidmc.org/ncfg/interestingfacts/interesting-facts-about-glycans

#glycotime #collagen

#Macaque #antibodies targeting #Marburg virus #glycoprotein induced by multivalent #immunization, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00155-24?af=R

Our #study advances the understanding of #orthomarburgvirus glycoprotein antigenicity and furthers efforts to develop candidate antibody countermeasures against these lethal viruses.

Referenced link: https://medicalxpress.com/news/2023-03-high-resolution-view-lymphocytic-choriomeningitis-virus.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-high-resolution-view-lymphocytic-choriomeningitis-virus.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1640811330549477376#m

RT by @physorg_com: First high-resolution view of lymphocytic choriomeningitis #virus #glycoprotein with a neutralizing antibody @ljiresearch https://linkinghub.elsevier.com/retrieve/pii/S2451945623000843 https://medicalxpress.com/news/2023-03-high-resolution-view-lymphocytic-choriomeningitis-virus.html

The #platelet #glycoprotein V is an important switching point for #hemostasis and #thrombus formation. This new finding could have great clinical potential.
#Biology #Medical #sflorg
https://www.sflorg.com/2023/03/med03242302.html

Nice talk on the importance of “sweet coatings“ to maintain an inflammatory environment in the osteoarthritic joint by @Mapineda_glyco@twitter.com part of @theglasgowcemi@twitter.com seminar series @UofGSMB@twitter.com #sketchnote #sketchnotes #inflamation #Glycoprotein
(to Xpost on mastodon)

#Glycoprotein

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