🩸 London woman off insulin for Type 1 diabetes after a single dose of experimental manufactured stem cells • CTVNews
｢ In a study published in the New England Journal of Medicine, researchers report that of the 12 patients who received a single dose of the stem cells, it eliminated the need for insulin in 10 for at least a year and stopped episodes of low blood sugar, or hypoglycemia, which can lead to dangerous complications, even death ｣
Pancreas getting a major software update! 🔬 Stem cell treatment helped 10/12 severe Type 1 diabetes patients ditch insulin therapy after a year. The lab-grown islet cells are apparently better at self-regulation than most of us are. Still in phase 3 trials, but promising!
Online Now! Hallmarks of stem cell aging https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00226-7?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Online Now! ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00224-3?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Online Now! An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00222-X?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Groundbreaking study reveals 95% oocyte viability during ambient temperature transport, unlocking new possibilities in reproductive research and stem cell technologies. Major breakthrough in understanding oocyte biology. #Reproduction #StemCells
Vertex Pharmaceuticals' stem cell breakthrough: 10 severe diabetics freed from insulin dependency! The catch? Lifelong immunosuppressants required to protect the new pancreatic cells. Still, trading multiple daily insulin shots for pills feels like meaningful progress. 🧬
Online Now! To play Paneth or goblet: Shapeshifting secretory cells read the room https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00229-2?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
We used NGN2-reprogrammed iPSC neurons with glutamatergic hyperactivity and tested phenytoin, perampanel, and carbamazepine.
Read the full paper here 👇
📄 Communications Biology
🔗 http://dx.doi.org/10.1038/s42003-025-08194-6
#Neurotech #SBI #DrugDiscovery #Epilepsy #Organoids #BrainOnAChip #stemcells #bioinformatics #invitromodeling
Last week we had the privilege to exhibit at the 2025 International Society for Stem Cell Research (ISSCR) Annual Meeting in Hong Kong.
It was a pleasure to meet many of our authors, reviewers, readers and some of our grant recipients.
Read our article collection, collated by @Dev_journal, highlighting recent research and review-type articles discussing the wide range of studies using stem cells:
https://journals.biologists.com/dev/collection/24984/Focus-on-stem-cells
#StemCells #Research #ISSCR #DevelopmentalBiology #Biology #Collaborate
Online Now! Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00221-8?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Fingertip-sized human hearts now beating inside pig embryos - talk about wearing your heart on someone else's sleeve! 🐷💖 These glowing chimera hearts survived 21 days and could revolutionize organ transplants.
Online Now! Human airway submucosal gland organoids to study respiratory inflammation and infection https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00193-6?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Online Now! Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00192-4?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Online Now! An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00191-2?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
New NIH technique regenerates eye tissue and tiny blood vessels—bringing hope for millions suffering from dry AMD. #VisionScience #StemCells #AMD
https://geekoo.news/dual-graft-technique-brings-hope-for-dry-amd-treatment/
Online Now! Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00187-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells
Join the Node Network @the_node, a global directory of developmental and stem cell biologists, designed to help you find speakers, referees, panel members and potential collaborators.
https://thenode.biologists.com/network/
#TheNode #StemCells #Biologists #Community #Global #Networking
What if fish could heal themselves better than we ever imagined? Scientists have just unlocked a hidden biological superpower. #Aquaculture #StemCells #MarineScience
https://geekoo.news/the-hidden-healing-power-beneath-salmon-skin/
#medicine #healthcare #StemCells #education
'Stem Cell Medicine: From Scientific Research to Patient Care is an essential educational resource for clinicians, scientists, healthcare providers, those in the nursing fields, medical students, and even the general public, seeking the most trusted and reliable stem cell information.'
https://today.uconn.edu/2025/05/first-stem-cell-medicine-course-for-clinicians-available-for-free/
