Structural and functional characterization of the #antigenicity of #influenza A virus #hemagglutinin subtype #H15, https://etidiohnew.blogspot.com/2025/07/structural-and-functional.html

R229I #substitution from #oseltamivir induction in HA1 region significantly increased the #fitness of a #H7N9 virus bearing NA 292K, Emerg Microbes Infect.: https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2373314

It indicated that through the fine-tuning of the HA–NA balance, R229I increased the fitness and change the #antigenicity of a H7N9 virus bearing NA 292 K. Public health attention of this mechanism needs to be drawn.

Mapping #Genetic #Markers Associated with #Antigenicity and Host #Range in #H9N2 #Influenza A Viruses Infecting #Poultry in #Pakistan https://pubmed.ncbi.nlm.nih.gov/38687107/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1LGAx__djGAJ9poBzWGqPtjEbBDtz4ipSRRPUplmgHEyyF_Ihj&fc=None&ff=20240430181504&v=2.18.0.post9+e462414

The presence of L216 in all H9N2 IAV isolates and T/V180 in four isolates in the receptor-binding site reveals the potential of these viruses to cross the species barrier to infect human or mammals.

#Antigenicity and #receptor affinity of #SARS-CoV-2 #BA286 #spike, https://www.nature.com/articles/s41586-023-06750-w #research #variants #VOI #vaccines #mAbs

#Antigenicity and #infectivity characterisation of #SARS-CoV-2 #BA286, Lancet Infect Dis.: https://doi.org/10.1016/S1473-3099(23)00573-X #research #science #covid19

''Results showed that KHM/23 exhibits similar #receptor #binding and #antigenicity as the early clade 2.3.2.1c #HPAI #H5N1 strain, and it does not bind to #human-like receptors.''