Population genomic analysis of common marmosets by Soni et al., taking into account twin births and hematopoietic chimerism, indicates a demographic contraction ~7,000 years ago, coinciding with ecological shifts in northeastern Brazil.

🔗 doi.org/10.1093/molbev/msaf119

#evobio #molbio

Catalán et al. analyse genomes of the European firefly, revealing a complex Pleistocene demographic history shaped by glaciation and sex-biased dispersal.

🔗 academic.oup.com/mbe/article/42/6/msaf123/8170119

#evobio #molbio

Simón, @gonzamoratorio.bsky.social et al. trace the evolution of ZAP, an antiviral protein targeting CpG-rich RNA that originated >400 Mya in the tetrapod–lungfish ancestor. Their findings point to complex coevolution of host antiviral defenses.

🔗 doi.org/10.1093/molbev/msaf135

#evobio #molbio

@ramencult.bsky.social‬ et al. use spatially explicit simulations and genomic data from Anopheles gambiae, showing that selection changes the joint distribution of allele frequency and geographic range.

🔗 doi.org/10.1093/molbev/msaf141

#molbio #evobio

ShiNyP by Huang et al. is an interactive platform for real-time SNP data analysis, with modules for QC, population genetics, and core collection development. It outputs publication-ready figures, tables, R objects, and AI-generated analytical reports.

🔗 doi.org/10.1093/molbev/msaf117

#molbio #biorxiv_evobio

In a new Review article, Hu et al. propose "Conservation Evolutionary Biology" as a new subdiscipline of conservation biology that integrates evolutionary history and ecosystem dynamics to guide biodiversity conservation.

🔗 doi.org/10.1093/molbev/msaf122

#evobio #molbio #conservation

Vaughan & Stadler develop a method to infer multitype population trajectories and apply it to MERS-CoV, revealing transmission patterns between camels and humans.

🔗 doi.org/10.1093/molbev/msaf130

#evobio #molbio #virus

Is MEGA-GPT heralding a new age of accessibility in bioinformatics with dedicated chatbots to help guide users? Read more in MBE's new Highlight: "MEGA into the New Generation of Computational Genetics"

🔗 doi.org/10.1093/molbev/msaf108

#evobio #molbio #bioinformatics #AI

MolBio Sommerfest 2025

KF Uni Graz, ZMB Gelände, Freitag, 27. Juni um 16:00 MESZ

Liebe Studis,
seid dabei, wenn wir am 27. Juni das Molbio Sommerfest feiern! Kommt vorbei zu einem entspannten Nachmittag voller Spaß, leckerem Essen und guter Gesellschaft. 🥳

📍 Ort: Humboldstraße 48 (ZMB Gelände)
🕓 Zeit: 16 - 23 Uhr

Wir freuen uns auf euch und einen unvergesslichen Sommerabend! ☀️

https://gancio.graz.events/event/molbio-sommerfest-2025

Using an experimental evolution platform @farhanrc.bsky.social & @chemtips.bsky.social show that tripartite antibiotic loops - sequential regimens involving three antibiotics - can resensitize bacteria to the 1st drug as multidrug resistance evolves

🔗 doi.org/10.1093/molbev/msaf115

#evobio #molbio

Jesse Bloom argues that the earliest available sequences of SARS-CoV-2 are not fully representative of actual early cases.

🔗 doi.org/10.1093/molbev/msaf118

#evobio #molbio #covid19 #sarscov2 #publichealth

Florence Débarre and Zach Hensel‬ offer a new perspective on available SARS-CoV-2 sequencing data, in particular regarding the earliest reported sequences.

🔗 doi.org/10.1093/molbev/msaf109

#evobio #molbio #covid19 #sarscov2 #publichealth

Yaddehige et al. present GBRAP, a parser and database for analyzing RefSeq genomes. This publicly available tool offers over 200 metrics per genome element with flexible retrieval, visualization, and export options.

🔗 doi.org/10.1093/molbev/msaf114

#evolbio #molbio #bioinformatics

John Allard‬ & Sudhir Kumar introduce MEGA-GPT, an AI assistant that aims to improve the usability of the feature-heavy MEGA software by guiding users through MEGA's options via natural language queries.

🔗 https://doi.org/10.1093/molbev/msaf101

#evobio #molbio #bioinformatics

Jones et al. investigate gene regulation in the social supergene of the fire ant, finding widespread impacts on chromatin accessibility, enhancer activity, and transcription.

🔗 doi.org/10.1093/molbev/msaf112

#evobio #molbio #bugsky

The June cover of Molecular Biology and Evolution features the work of de Bakker et al., who studied the developmental genetics of amniote limb phenotypes.

🔗 doi.org/10.1093/molbev/msaf113

📷 Gerda Lamers

#evobio #molbio #evodevo

🌼 Flowers unfold with surprising precision, despite unruly genes

https://phys.org/news/2025-05-unfold-precision-unruly-genes.html

#flowers #plants #botany #genomics #omics #molbio #auxin

Thompson et al. model gene expression as a binary trait to examine transcriptome turnover across Drosophila species, inferring gains and losses of organ-specific expression.

🔗 doi.org/10.1093/molbev/msaf106

#molbio #evobio #transcriptomic #drosophila

Policarpo et al. use phylogenetic and synteny data to identify 19 teleost-to-teleost horizontal gene transfers in 11 orders, involving genes linked to immunity or pore formation; this suggests eukaryote-to-eukaryote HGT has shaped teleost evolution.

🔗 doi.org/10.1093/molbev/msaf107

#evolbio #molbio #fish

Okuno et al. assemble male genomes for three spiny rat species, tracing Y chromosome loss and gene translocation. Authors show that segmental duplications and rearrangements enabled preservation of Y-linked genes on the X.

🔗 doi.org/10.1093/molbev/msaf102

#molbio #evobio #sexchromosomes