#podocyte

Bernhard Schermercilib@social.cologne
2025-07-26

Please share …. 🙏
📣 Very soon, we’ll have an open PhD position starting in fall 2025 — this time not on cilia, but on YAP & TAZ in podocytes and their regulation via LLPS. Interested candidates are welcome to contact us directly.

Supervision by Inês Cabrita and me, embedded within PodoSigN!
Within this project, close collab. with Beate Vollenbröker‘s team.

#Podocyte #Trr422 #Fsgs #Nephrolab #PhdPosition #Biology #Genetics #LLPS #HippoSignaling #phd

@CECAD
@cilia

Cells expressing Yap (stained green). Left side without  condensate induction, right side two minutes after condensate induction, now filled with green dots.
Bernhard Schermercilib@social.cologne
2025-03-27

📣📣📣 Latest news from the NephroLab Cologne – more specifically, from our 🦛 Hippo- Team:
Our snRNA-Seq study on YAP and TAZ in kidney podocytes is now online open access in JASN! 🥳 🎉 🐙
Huge thanks to everyone on the team and the incredibly thorough reviewers at JASN!

Link: journals.lww.com/jasn/abstract

#HippoSignaling #YAP #TAZ #Kidney #Kidneydisease #Science #snRNASeq #cellsignaling #FSGS #podocyte #Nephrology #Niere #Nephrolab #Nephrologie

@ukkoeln @UniKoeln @CECAD

Detail of Figure 1: Schematic illustrating the strategy for isolating single nuclei from purified murine glomeruli, with podocyte-specific deletion of YAP or TAZ. UMAP plots show distinct clusters of podocytes.
2023-12-30

Hallo zusammen! In den nächsten Wochen poste ich hier kleine Cartoons und Updates zu meinem Nephrologie Lehreprojekt zum Thema Akute Nierenfunktionseinschränkung / Acute kidney injury für Medizinstudierende der @ChariteBerlin
Ich freue mich über Ideen, Feedback, Wünsche und Kritik, insbesondere von den Studienrenden!

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#nephrologie #niere #medizinstudium #medizin #lehre #nephrology #nephrologyart #podocyte #kidney #medicine #chariteberlin #education #foamed #medicalstudent #medicalschool

Bernhard Schermercilib@social.cologne
2023-10-01

The Nephrolab :koeln: stepping into the world of Kidney organoids … fascinating little creatures 😊 that kept me tied to the bench for the past few weeks 😉

Attached are a few snapshots from last night.

#Kidney #Nephrology #StemCells #ThreeR #RRR #Niere #Podocyte
@UniKoeln

Collage of three photos: One image displays small cell culture aggregates swimming in a plastic tube. Another picture showcases individual organoids, roundish white-yellow structures with a darker nucleus floating in liquid. At the bottom, there's a microscopic image showing green cells of tubules and clusters of pink nuclei expressing WT1.
Bernhard Schermercilib@social.cologne
2023-08-11

📣 Thrilled to share: Lioba and Inês' study on NUPs and the 🦛 effectors YAP/TAZ is now live at HMG - adding another puzzle piece to the role of YAP/TAZ in FSGS.

Congrats and a huge THANKS to the entire team for the fantastic work. 🙌🔬

academic.oup.com/hmg/advance-a

#Research #Science #Podocyte #FSGS #RareDisease #Kidney #Nephrology #Genetics #openaccess

Schematic illustration of NUP205 as part of the Nuclear Pore. The loss of NUP205 impairs the nuclear import and activity of YAP/TAZ.  
(figure created with BioRender.com)
Bernhard Schermercilib@social.cologne
2023-07-13

Just met a lonely podocyte - suffering from foot process effacement 😬

#Nephrology #kidney #Podocyte #Lisbon #medibubble #CellBiology

Street art on the banks of the Tagus / Tejo … a violet face with large eyes and an octopus-like chin looking angry.
Bernhard Schermercilib@social.cologne
2023-03-08

📣 Time to toot some Hippo🦛 & Podocyte🐙 - News:

Nucleoporins and the Hippo signaling effectors YAP/TAZ might balance each other to keep podocytes sound.

Please find the latest preprint from our CRU329 project:

biorxiv.org/content/10.1101/20

A huge THANK YOU to our Hippo team working hard to decipher more details.

#Podocyte #FSGS #Nephrology #HippoSignaling #Nucleoporin #CellBiology #KFO329 #CRU329 #RareDisease #GlomerularDisease

@UniKoeln @CECAD
@nephrology @biorxivpreprint

Our working hypothesis in a nutshell: schematic drawing of the nuclear pore highlighting the position of NUP205 right in the center and showing the Hippo effectors YAP/TAZ as "cargo" shuttling back and forth through the pore.
(created with biorender.com).
Bernhard Schermercilib@social.cologne
2023-02-11

@bioRxiv_cellbiol

David‘s and Amer‘s latest ‚podographs‘ 🔬📸

Below:
My personal favorite pic from the preprint.

#fsgs #podocyte #nephrology #FluorescenceFriday #microscopy #CellBiology #ScienceMastodon

Fluorescence microscopic picture (STED) of a glomerular capillary: Nephrin, which is localized at the contact between foot processes, appears as a green garland, tubulin in primary processes as magenta cables.

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