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Tom Kindlontomkindlon@disabled.social
2026-02-13

News Release 11-Feb-2026
Vanderbilt Health to lead expanded multisite study of immunomodulation in long COVID

eurekalert.org/news-releases/1

The Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary symptoms of #LongCOVID (REVERSE-LC)

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

News Release 11-Feb-2026 Vanderbilt Health to lead expanded multisite study of immunomodulation in long COVID Grant and Award Announcement Vanderbilt University Medical Center FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail Vanderbilt Health to lead expanded multisite study of immunomodulation in long COVID image: Members of the Vanderbilt Health team are evaluating the efficacy of the immunomodulatory drug baricitinib for treating the persistent neurological and cardiopulmonary symptoms of long COVID. view more Credit: (photo by Donn Jones) Since the virus that causes COVID-19 emerged in late 2019, there have been over 780 million cases worldwide and over 7 million deaths. Despite the development of vaccines and effective therapeutics, millions of patients experience an often-devastating, post-acute infection syndrome known as long COVID (LC). In the United States, it is estimated that up to 20 million adults with LC experience persistent neurocognitive impairments (NCI) and cardiopulmonary symptoms such as dyspnea (shortness of breath) and exercise intolerance for months to years after having COVID-19. The public health burden of LC is estimated to be the largest seen from an emerging disease in the past century, yet there remain no effective interventions.
Tom Kindlontomkindlon@disabled.social
2026-02-13

"WHO/Europe, with support from the EU, has developed 8 long COVID myth-busters that use evidence-based information and real patient stories to clear up these myths and promote scientifically accurate understanding."

who.int/europe/news-room/event

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

@novid #novid

Europe Home/Newsroom/Events/Myth-busters: debunking long COVID myths and misconceptions © Myth-busters: debunking long COVID myths and misconceptions 30 January – 31 March 2026 Русский Deutsch Misconceptions about post COVID-19 condition, more commonly known as long COVID, continue to hinder diagnosis, prevention, care and rehabilitation. To debunk these myths and misconceptions, WHO/Europe, with support from the European Union, has developed 8 long COVID myth-busters that use evidence-based information and real patient stories to clear up these myths and promote scientifically accurate understanding.
Tom Kindlontomkindlon@disabled.social
2026-02-12

"we observed sustained negative impacts of PCC on health outcomes 2.5 years after initial COVID-19 in non-hospitalised individuals, despite minor improvements over time."

link.springer.com/article/10.1

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Long-term health outcomes and risk factors for low self-rated health in non-hospitalised adults with post-COVID-19 condition: a 2.5-year cohort study — Törnberg et al. "we observed sustained negative impacts of PCC on health outcomes 2.5 years after initial COVID-19 in non-hospitalised individuals, despite minor improvements over time."
Tom Kindlontomkindlon@disabled.social
2026-02-12

SARS-CoV-2 reinfections and subsequent risk of hospital-diagnosed post-acute sequelae in Denmark (2020–2022): a nationwide cohort study

sciencedirect.com/science/arti

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

SARS-CoV-2 reinfections and subsequent risk of hospital-diagnosed post-acute sequelae in Denmark (2020–2022): a nationwide cohort study — Khurana et al. "Of 4,418,544 individuals, 6942 (0.16%) were diagnosed with long COVID." "diagnoses were made in hospital settings and thus predominantly capture severe presentations. As a result, only a fraction of individuals experiencing postacute sequelae are likely represented, underestimating the true risk"
Tom Kindlontomkindlon@disabled.social
2026-02-11

From the US:

Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks

alz-journals.onlinelibrary.wil

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

@novid #novid

Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks — Huize Pang et al. "patients exhibited enlarged ChP and reduced blood perfusion" "In addition to structural alterations, we observed decreased blood flow in the ChP" "findings indicate a regionally selective vulnerability of the ChP in long COVID"
Tom Kindlontomkindlon@disabled.social
2026-02-11

From Australia:

Non-invasive electrodiagnostic testing for small fibre neuropathy in long COVID-19

neurologyopen.bmj.com/content/

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver
#SFN

Non-invasive electrodiagnostic testing for small fibre neuropathy in long COVID-19 — Anthony Khoo et al. "Notably, we demonstrated different combinations of abnormality among the four small fibre neuropathy tests illustrating the benefit of multimodal SFN testing protocols which interrogate different small nerve fibres."
Tom Kindlontomkindlon@disabled.social
2026-02-11

From Colombia

NET Biomarkers in COVID-19 and Post-COVID Syndrome: a Comprehensive Analysis

link.springer.com/article/10.1

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19

NET Biomarkers in COVID-19 and Post-COVID Syndrome: a Comprehensive Analysis — Monsalve et al. "Our findings revealed a significant increase in NET biomarkers during acute COVID-19 that persisted in PCS. This pattern was consistent with the in vitro study, where sera from PCS patients induced NET release."
Tom Kindlontomkindlon@disabled.social
2026-02-10

News Release 10-Feb-2026
"Long COVID linked to Alzheimer’s disease mechanisms: Diseases cause damage in some of the same ways"

eurekalert.org/news-releases/1

New US research.

Full paper:
alz-journals.onlinelibrary.wil

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

@novid #novid

News Release 10-Feb-2026 Long COVID linked to Alzheimer’s disease mechanisms Diseases cause damage in some of the same ways Peer-Reviewed Publication NYU Langone Health / NYU Grossman School of Medicine FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail The increased size of, and lesser blood supply to, a key brain structure in patients with Long COVID tracks with known blood markers of Alzheimer’s disease and greater levels of dementia, a new study finds. Led by NYU Langone Health researchers, the study concerns the choroid plexus (CP), a network of blood vessels lined by cells that produce cerebrospinal fluid, which cushions the brain and forms a protective barrier between the fluid and the bloodstream. The CP regulates immune system responses (inflammation) and waste clearance in the brain. Past studies show that the COVID-19 virus can damage the cells lining CP blood vessels. Published online Feb. 10 in Alzheimer's & Dementia, the new work found that patients reporting Long COVID had a 10% larger CP than those who had fully recovered from an initial infection with SARS-CoV-2, the virus that causes COVID-19 disease. Further, CP size increases tracked with blood levels of proteins that increase as Alzheimer’s disease worsens, such as pTau217, and with blood levels of others that rise in response to brain injury, like glial fibrillary acidic protein.
Tom Kindlontomkindlon@disabled.social
2026-02-10

Maryland may soon become the first U.S. state to directly support Long COVID research and development

thesicktimes.org/2026/02/06/ma

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

The Sick Times "Maryland considers Long COVID innovation bill" Maryland may soon become the first U.S. state to directly support Long COVID research and development. The proposed bill doesn’t allocate government funding to Long COVID research. It uses existing infrastructure in the state to create a system for distributing potential gifts from private donors.
Tom Kindlontomkindlon@disabled.social
2026-02-08

In case you missed this big, exciting news:

Germany Declares 'National Decade Against Post-Infectious Diseases'

www-bmftr-bund-de.translate.go

From February 2026 Massachusetts ME/CFS & FM Association newsletter

massme.monkeypod.io/mailcoach/

#MEcfs @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#CFS #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome
@mecfs

Germany Declares 'National Decade Against Post-Infectious Diseases' The German government has launched a ten-year initiative to find the underlying biological mechanisms and effective treatments for post-infective diseases. The 'National Decade Against Post-Infectious Diseases' initiative commits 500 million Euros over ten years ($540 million) and will specifically focus on ME/CFS. Federal Research Minister Dorothee Bär, in announcing the strategy, noted that "The need for research is enormous: for ME/CFS and post-viral autoimmune diseases there are still no simple solutions or therapies, and previous studies demonstrate the complexity of the disease mechanisms."
Tom Kindlontomkindlon@disabled.social
2026-02-08

RECOVER Research Review Webinar: Long COVID trajectories in adults, February 10

Links:
rtiorg.zoom.us/webinar/registe

recovercovid.org/r3-seminar-se

From February 2026 Massachusetts ME/CFS & FM Association newsletter

massme.monkeypod.io/mailcoach/

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

RECOVER Research Review Webinar: Long COVID trajectories in adults, February 10 Researchers in the NIH's RECOVER (Researching COVID to Enhance Recovery) project will present findings about the clinical presentation of Long COVID and how it changes over time on Tuesday, February 10, at 12:00 PM (ET) . Register here. Previous research review seminars can be viewed here.
Tom Kindlontomkindlon@disabled.social
2026-02-07

Australian Winter Olympic athletes wearing an N95 mask as they boarded the bus to head to the Opening Ceremony
👏👏👍👍

Hashtags:

@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
#COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #auscovid19
#Masking #Maskup

1/

Photo of athletes wearing blue and yellow wearing masks
Tom Kindlontomkindlon@disabled.social
2026-02-04

New from international research group

Immunoglobulin G Complexes from Post-infectious ME/CFS, including post-COVID ME/CFS Disrupt Cellular Energetics and Alter Inflammatory Marker Secretion

sciencedirect.com/science/arti

#MEcfs #CFS #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome
@mecfs
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

1/

Abstract Background Autoimmunity is a key clinical feature in both post-infectious Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of COVID (PASC). Passive transfer of immunoglobulins from patients' sera into mice induces some clinical features of PASC. However, the physiological effects of immunoglobulins on cellular alterations remain elusive. In this study, we tested the potential effects of immunoglobulins from ME/CFS patients on endothelial cell dysfunction. Methods We have isolated immunoglobulins from 106 individuals, including ME/CFS (n=39), PCS-CFS (n=15), MS (n=20) patients, and healthy controls (n=41). Protein composition of the isolated immune complexes was studied using mass spectrometry. The effect of isolated immune complexes on mitochondria was evaluated using confocal microscopy and a Seahorse XFe96 Extracellular Flux Analyzer, and the impact on inflammatory cytokine secretion was studied using a multiplex bead-based assay. Results Here, we demonstrate that IgG isolated from post-infectious ME/CFS patients selectively induces mitochondrial fragmentation in human endothelial cells and alters cellular energetics. This effect is lost upon cleavage of IgG into its Fab and Fc fragments.
Tom Kindlontomkindlon@disabled.social
2026-02-04

The Stigma of self-report in health research: Time to reconsider what counts as “Objective” by Nisreen A. Alwan nisreen@mastodon.online

journals.plos.org/globalpublic

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

The Stigma of self-report in health research: Time to reconsider what counts as “Objective” — Nisreen A. Alwan "The assumption is that people misremember, exaggerate, or misinterpret their symptoms. But what if the problem lies not in the type of data, but in our unwillingness to trust this mode of reporting without adequate justification for such mistrust?"
Tom Kindlontomkindlon@disabled.social
2026-02-03

"the relationship between reporting persisting symptoms & increased healthcare consumption could not be explained by cognitive-behavioural factors, depressive symptoms or neuropsychological functioning."

link.springer.com/article/10.1

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

Healthcare Consumption and Work Absenteeism of Individuals With and Without Persistent Complaints After COVID-19: The Role of Cognitive-Behavioural Factors, Neuropsychological Functioning and Depressive Symptoms — Verveen et al. "the relationship between reporting persisting symptoms and increased healthcare consumption could not be explained by cognitive-behavioural factors, depressive symptoms or neuropsychological functioning."
Tom Kindlontomkindlon@disabled.social
2026-02-03

A cross-continental comparative analysis of the neurological manifestations of Long COVID

frontiersin.org/journals/human

Screenshot from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

A cross-continental comparative analysis of the neurological manifestations of Long COVID — Jimenez et al. "This study found that overall, cognitive and sleep disorders, headache and dizziness were the most frequent neurologic symptoms as well as fatigue." "Neuro-PASC affects young and middle-aged adults in their prime, causing significant detrimental impact on the workforce, productivity and innovation all over the world."
Tom Kindlontomkindlon@disabled.social
2026-02-02

Diminished EBV-Specific Humoral Immunity is Associated with Neuropsychiatric Long COVID Development up to 12 Months
#PostCOVID19 Symptom Onset

biorxiv.org/content/10.64898/2

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Diminished EBV-Specific Humoral Immunity is Associated with Neuropsychiatric Long COVID Development up to 12 Months Post-COVID-19 Symptom Onset — Philip Samaan et al. "our study highlights that neuropsychiatric long COVID symptoms may not be attributable to alterations in SARS-CoV-2-specific cellular or humoral immunity. However, diminished EBV-specific humoral immunity emerged as a potential risk factor for neuropsychiatric long COVID development"
Tom Kindlontomkindlon@disabled.social
2026-02-02

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

onlinelibrary.wiley.com/doi/10

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID — Samuel B. K. Keat et al. "We found that plasma concentrations of MASP-2/C1Inh were significantly increased in patients with long COVID relative to healthy convalescent individuals with no persistent symptoms after contemporaneous infection with SARS- CoV-2 (p = 0.0003)."
Tom Kindlontomkindlon@disabled.social
2026-02-02

Imbalance of Excitatory and Inhibitory Neurotransmitter Systems in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

preprints.org/manuscript/20260

Screenshot from latest Science for ME weekly update

#MEcfs #CFS #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome @mecfs @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

Imbalance of Excitatory and Inhibitory Neurotransmitter Systems in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome — Klaus J. Wirth and Carmen Scheibenbogen Hypothesis paper. "This paper reviews current knowledge on neurotransmitter systems implicated in ME/CFS and Long COVID, focusing on potential mechanisms of dysregulation and their roles in disease pathology and symptom generation, as well as implications for treatment."
Tom Kindlontomkindlon@disabled.social
2026-01-31

"Those Who Were Already Here: Learning to Live Inside a History I Did Not Choose"

centerleftstack.substack.com/p

Someone with long Covid eloquently thanks those with ME/CFS who have supported with advice, etc. the Long Covid new arrivals with similar symptoms & impairments

#MEcfs @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#CFS #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome @mecfs

Those Who Were Already Here Learning to Live Inside a History I Did Not Choose Fred Rossi Dec 24, 2025 Arrival Without a Map When I first began trying to understand what was happening to my body, everything felt new. Not just new to me, but new in the way that feels destabilizing. As if the ground itself had shifted and no map existed. Long COVID arrived wrapped in uncertainty. Doctors hesitated. Research lagged. Language failed. Each symptom seemed to require explanation from scratch. I thought I was living at the edge of something unprecedented. That belief did not last. Gradually, almost accidentally, I began encountering people who spoke about my present as if it were familiar. They used words I was just learning. Post-exertional malaise (PEM). Pacing. Crashes. Baseline. They described patterns that mirrored my days with unsettling precision. They were not speculating. They were remembering. This was my introduction to the ME/CFS community. A community that had been here long before I arrived. Recognition, Not Surprise The people who live with ME/CFS did not greet Long COVID with surprise. They greeted it with recognition.

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