#Charit%C3%A9Virology

2025-04-14

While little is known about the mysterious #Oropouche virus in Latin America, a number of deaths have been reported along with impacts on unborn babies. A #CharitéBerlin study has discovered that the pathogen is more widespread than previously thought.

👉 charite.de/en/service/press_re

#CharitéVirology #CharitéPaper #medicine #science #research #ScienceMastodon #MedMastodon #Medibubble #LatinAmerica #travelling #virology

Map of Latin America, with different regions shaded in a color scale from light yellow (low infection risk) to dark purple (high infection risk). The Amazon rainforest and other regions along the coast of Brazil, in Central America, and in the Caribbean are shown in purple. © Charité | Anna Frühauf (image taken from the original publication in The Lancet Infectious Diseases)
2025-04-14

Über das #Oropouche-Virus in #Lateinamerika ist bisher wenig bekannt, es gibt aber Hinweise auf einzelne Todesfälle & mögliche Folgen für ungeborene Kinder. Eine #CharitéBerlin-Studie zeigt jetzt: Der Erreger ist in der Region weiter verbreitet als gedacht.

👉 charite.de/service/pressemitte

#CharitéVirology #CharitéPaper #Medizin #Forschung #Wissenschaft #MedMastodon #Virologie #Medibubble #Reisen

Landkarte von Lateinamerika, unterschiedliche Gegenden sind eingefärbt in einer Farbskala von hellgelb (niedriges Infektionsrisiko) bis dunkellila (hohes Infektionsrisiko). Amazonasgebiete und weitere Bereiche an der Küste Brasiliens, in Zentralamerika und in der Karibik sind lila dargestellt. © Charité | Anna Frühauf (Abbildung aus der Originalpublikation in The Lancet Infectious Diseases)
2024-12-18

📢 New research from #CharitéBerlin sheds light on the origin of the hepatitis E virus!

🐭 According to the study, the virus probably originated in rodents and found its way to humans via hoofed animals. Read more in our paper spotlight:

👉 charite.de/en/research/paper_s

#medicine #research #science #ScienceMastodon #MedMastodon #CharitéPaper #CharitéVirology #HEV #hepatitis

Electron micrograph depicting numerous spheroid-shaped hepatitis E viruses (HEV): Greyscale image with light, small spheres on a dark grey background. Two thread-like structures next to it. © CDC
2024-03-28

The @WHO has appointed the Institute of Virology at #CharitéBerlin as a member of the new WHO #Coronavirus Network (CoViNet). The network of reference laboratories aims to detect and monitor #SARSCoV2, #MERS and other viruses at an early stage to support the development of #WHO public health strategies. The Institute is one of 33 laboratories worldwide to contribute their expertise.

👉 charite.de/en/research/themes_

#medicine #MedMastodon #CoViNet #PublicHealth #CharitéVirology #diagnostics

A scientist in a full-body protective suit sits at a cell culture bench. She is holding a plastic flask filled with red cell culture medium in her hands. © Charité | Arne Sattler
2024-02-26

The #MERS coronavirus can be transmitted from dromedaries to humans and causes severe pneumonia in some people. A study by #CharitéBerlin & the University of Nairobi now shows that the probability of transmission in Kenya 🇰🇪 is highest during the two dry seasons.

👉 charite.de/en/research/paper_s

@mamueller #CharitéPaper #science #research #ScienceMastodon #CharitéVirology #Africa

Eight dromedaries stand and lie on sandy ground in front of a tree in the evening sun, surrounded by a wooden fence © Charité | Marcel A. Müller
2024-02-26

Das #MERS-Coronavirus kann von Dromedaren auf Menschen übertragen werden und zum Teil schwere Lungenentzündungen auslösen. Eine Studie der #CharitéBerlin & der Universität Nairobi zeigt jetzt, dass die Übertragungswahrscheinlichkeit in Kenia 🇰🇪 während der zwei Trockenzeiten am höchsten ist.

👉 charite.de/forschung/paper_spo

@mamueller #CharitéPaper #Forschung #Wissenschaft #ScienceMastodon #CharitéVirology #Afrika

Acht Dromedare stehen und liegen auf sandigem Untergrund vor einem Baum in der Abendsonne, umgeben von einem Holzzaun © Charité | Marcel A. Müller
Marcel.A.Müllermamueller@mstdn.science
2024-02-18

Our #DFG-funded project reveals bi-phasic #MERS-CoV circulation in nomadic #camels in #Kenya Important info to prevent human spillovers @dfg_public @ChariteBerlin @DZIF_ #ChariteVirology #CEMA_Africa wwwnc.cdc.gov/eid/article/30/3

Victor M. Cormanvmcorman@mstdn.science
2024-01-15

BA.2.86 & its descendant, JN.1, of #SARSCoV2 dominate the winter wave. But why?
Using live virus neutralisation & sera taken in fall 2023 we found clear neutralisation escape against recent variants but no specific escape for BA.2.86/JN.1.
➡️ Neutralisation escape doesn't seem to explain the JN.1 increase. Further studies may find the driving force instead.

New publication out:
eurosurveillance.org/content/1
Congrats to Lara and Barbara!
#CharitéVirology #Eurosurveillance @ChariteBerlin

Victor M. Cormanvmcorman@mstdn.science
2024-01-12

Our first publication in 2024
"Deep RNA sequencing of muscle tissue reveals absence of viral signatures in dermatomyositis" is now out in #FreeNeuropathology #CharitéVirology
@ChariteBerlin

doi.org/10.17879/freeneuropath

Experimental study design. The study cohort, including subgroups and information on autoantibodies, is given in the upper panel. Histological work-up of DM skeletal muscle samples shows perifascicular atrophy (HE, arrows). Immunohistochemical staining of type I IFN-inducible proteins ISG15 and MxA demonstrates a perifascicular staining pattern with SIGLEC1-positive macrophages (brown) in close proximity to ISG15 positive muscle fibers (red). Deep sequencing of DM patients’ skeletal muscle biopsies only revealed viral reads derived from column-based extraction and library preparation kit contaminations. (aDM: adult dermatomyositis, jDM: juvenile dermatomyositis, NDC: non-diseased controls, NA: No autoantibody testing, yrs: years)
2024-01-03

An international team headed by #CharitéBerlin is looking to #biodiversity 🐭 🦟 🦠 to better gauge whether pathogens could pass from animals to humans. The goal is to help prevent #epidemics. The EU 🇪🇺 has pledged 4 million euros to support the project.

👉 charite.de/en/service/press_re

@unihannover #ScienceMastodon #research #CharitéVirology #ZOE #zoonoses #HorizonEurope

A Charité researcher in a blue sweatshirt and baseball cap stands in a field overgrown with banana plants in Costa Rica. He examines a metal rodent trap about 15 cm long with gloved hands. It is empty. © Charité | Andres Moreira-Soto
Victor M. Cormanvmcorman@mstdn.science
2023-11-30

The result of fruitful joint work :

"...Establishment of West Nile virus in a large urban area in Europe (= #Berlin )".
eurosurveillance.org/content/1

#WNV #Arbovirus #CharitéVirology #Eurosurveillance
@ChariteBerlin

Victor M. Cormanvmcorman@mstdn.science
2023-11-09

Characterization of intrinsic and effective fitness changes caused by temporarily fixed mutations in the SARS-CoV-2 spike E484 epitope and identification of an epistatic precondition for the evolution of E484A in variant Omicron. #CharitéVirology @ChariteBerlin

doi.org/10.1186/s12985-023-021

2023-10-17

#Ecuador 🇪🇨 was a hotspot of the #COVID19 pandemic in 2020, despite introducing contact restrictions early on. One issue: high mobility in the informal labor sector.

Now virological evidence by researchers from #CharitéBerlin and Ecuador suggests that contact restrictions nevertheless reduced the spread of #SARSCoV2 to some degree.

👉 charite.de/en/research/paper_s

#CharitéPaper #CharitéVirology #Science #Research #ScienceMastodon #Corona

Two maps of Ecuador with differently colored provinces. The colors (transition from blue to yellow) encode the number of distinct SARS-CoV-2 lineages. Fewer distinct viral lineages circulated during strict contact restrictions (left) than during more lax measures (right). © Charité | Andres Moreira-Soto
2023-10-17

#Ecuador 🇪🇨 war 2020 ein Hotspot der #COVID19-Pandemie, obwohl es schon früh Kontaktbeschränkungen einführte. Ein Problem: Die hohe Mobilität im informellen Arbeitssektor.

Die virologische Analyse eines Forschungsteams der #CharitéBerlin und aus Ecuador deutet jetzt darauf hin, dass die Kontaktbeschränkungen dennoch die Ausbreitung von #SARSCoV2 zu einem gewissen Grad gedämpft haben.

👉 charite.de/forschung/paper_spo

#CharitéPaper #CharitéVirology #Wissenschaft #Forschung #ScienceMastodon #Corona

Zwei Landkarten von Ecuador mit unterschiedlich eingefärbten Provinzen. Die Farben (Übergang von Blau zu Gelb) kodieren die Anzahl der unterschiedlichen SARS-CoV-2-Linien. Während strikter Kontaktbeschränkungen (links) zirkulierten weniger unterschiedliche Viruslinien als während laxerer Maßnahmen (rechts). © Charité | Andres Moreira-Soto
Victor M. Cormanvmcorman@mstdn.science
2023-10-06

Finally published at #Science:

"Mapping SARS-CoV-2 antigenic relationships and serological responses"

science.org/doi/10.1126/scienc

Congrats to Barbara, Sam, and all others.
@ChariteBerlin
#CharitéVirology #UniversityCambridge #DukeUniversity

Victor M. Cormanvmcorman@mstdn.science
2023-10-05

Interested in Hepatitis A Virus evolution? Check out our just published study on Hepatitis A Virus in Alpacas from Bolivia. In this study, we detected RNA of distinct HAV in ≈9% of New World camelids and HAV antibodies in ≈64%. Complete-genome analysis of the Alpaca HAV suggests a long association of these viruses with alpacas as hosts.
#HAV #CharitéVirology #EmergingInfectiousDiseases @ChariteBerlin
@bih_charite
wwwnc.cdc.gov/eid/article/29/1

Phylogenetic trees with the Alpaca HAV clustering within the Hepatovirus A clade.
2023-09-26

Decreases in biodiversity can promote the spread of viruses, as shown by a study by #CharitéBerlin & Leibniz-IZW on the impact of rainforest clearing on mosquitoes and the viruses they carry.

👉 charite.de/en/service/press_re

#research #science #CharitéVirology

2023-09-26

Die Abnahme der Artenvielfalt kann die Verbreitung von Viren begünstigen – das zeigt eine Studie von #CharitéBerlin & Leibniz-Institut für Zoo- und Wildtierforschung zur Auswirkung von Regenwaldrodung auf Stechmücken und deren Viren.

👉 charite.de/service/pressemitte

#forschung #wissenschaft #CharitéVirology

2023-09-26

Die Abnahme der Artenvielfalt kann die Verbreitung von Viren begünstigen – das zeigt eine Studie von @CharitéBerlin & @IZWberlin zur Auswirkung von Regenwaldrodung auf Stechmücken und deren Viren. #forschung #wissenschaft #CharitéVirology
nachrichten.idw-online.de/2023

Foto darf nur im Zusammenhang mit der Pressemitteilung verwendet werden.
Victor M. Cormanvmcorman@mstdn.science
2023-09-15

Our most recent publication on #HepatitisE whole genome sequencing: We analysed a 40-year old camel HEV and found evidence for virus compartmentalization within the cns in humans with chronic #HEV infections.
#CharitéVirology #PEI #LaborBerlin #JCV #Zoonoses @ChariteBerlin

authors.elsevier.com/a/1hluf4x

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