#Neutralization of #SARS-CoV-2 #KP1, #KP11, #KP2 and #KP3 by #human and murine #sera
Source: npj Vaccines, AbstractWe report SARS-CoV-2 KP.1, KP.1.1, KP.2 and KP.3 neutralizing antibody titers. They displayed increased immune evasion compared to JN.1, especially KP.1 and KP.3, for participants who experienced BF.7/BA.5.2 breakthrough infection or received bivalent (delta/BA.5) vaccine boosting. Second XBB sub-variants breakthrough infection enhanced the neutralization…
In Österreich sind ersten Lieferungen des Herbstimpfstoffes gegen #Corona bzw. #Covid19 eingetroffen.
Allerdings fährt die EU mit EMA & BioNTech und gegen die #JN1 Variante eine andere Strategie als die USA: Dort sprach die FDA noch Anfang Juni eine Empfehlung für eine JN.1-Variante aus, um nur wenige Tage später auf #KP1 zu wechseln.
Aktuell wirkt auf mich die KP-Linie als Treiber für die #Sommerwelle wesentlich relevanter.
https://allcoronavirusesarebastards.digitalpress.blog/die-herbstimpfung-2024-ist-schon-da/
#Singapore, #Clinics pump in more #resources to combat spike in #COVID19 cases, respiratory #infections https://www.channelnewsasia.com/singapore/covid19-respiratory-infections-surge-kp1-kp2-flirt-variant-clinics-doctors-resources-4366136
Singapore has seen a jump in COVID-19 infections in recent weeks, with the new #KP1 and #KP2 strains, part of the family of “#FLiRT” #variants, accounting for about two-third of the cases.
Tracking #SARSCoV2 #Lineages - Globally
@rajlabn
KP3 is rising in BC and is much more immune evasive
Top lineages -#30DayTrends (#G30)
KP.2 (12.7%)
KP.3 (11.6%)👀
JN.1.7 (6.9%)
JN.1 (6.8%)
JN.1.16 (5%)
JN.1.4 (4.9%)
JN.1.16.1 (4.6%)
KP.1.1 (3.6%)
KS.1 (2.8%)
JN.1.32 (2.7%)
LB.1 (2.7%)
https://threadreaderapp.com/thread/1791943765667795391.html
https://public.tableau.com/app/profile/raj.rajnarayanan/viz/ConvergentLineages-VariantSoup-World/G20
10. Gin and Tonic (02:57)
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9. In Your Feelings (03:30)
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7. Mother’s Day ft. @Beyonce (03:44)
[Produced by Derek Dixie, Alex Delicata, Robyn Fenty & Beyonce Knowles-Carter]
6. Angela’s Interlude ft. Angela Bassett (00:52)
[Produced by Rob Bisel]
5. Still My Boo ft. Daniel Caeser (03:43)
[Produced by Robyn Fenty, Rob Bisel, Carter Lang & Jermaine Dupri]
4. You Could’ve Fooled Me (04:04)
[Produced by Two Fresh]
3. Men Send Love (02:53)
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1. Wait a Minute (01:00)
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Beyond thrilled to announce...
Kudos
My debut studio album will be released this Friday, May 3rd
Update for 3/1/2024!
Good Morning SARS2PAians! ❄️
Welcome to March, after Leap Day 🐇🐏🐸!
There's no new CDC stuff today.
__________
VOCs
Nothing currently new with VOCs, JN.1 all over the place nationally: https://ibb.co/GncBGTR
and in PA of course.: https://ibb.co/yS1wq0c
Scientists are still watching JN.1.11, and even though it's sort of fizzled out itself, its children are now moving progressively faster as it develops.
Faster than its parent, JN.1.11.1 is moving along and is being found in most new sampling.
Along with it, JN.1.11.1.1, which is shortened to KP.1, has great potential to make a dent in its grandparent's leaderboard status.
I'm also seeing a LOT of JN.1.16 both here in Canada by the latest sequencing experts. I'm just going to make a mental note of JN.1.16 because it and also JN.1.11.1 are both moving sorta quickly through Canada and are also found in the NY/NJ area.: https://ibb.co/R3Tmstt
None of these are "major eathshaking variants" but to have something faster NOW will bump numbers back up for Spring and we DO NOT want that!
Nothing all that significant in PA yet. No JN.1.16, JN.1.11, JN.1.11.1, or KP.1.
__________
Wastewater
Nationally, SARS2 material found in wastewater is DROPPING again!: https://ibb.co/3RM4DDk
This is great. We are starting to approach the lower levels of previous years.: https://ibb.co/pbHnDDJ
Regionally, all regions are down except for the Midwest which is bumping upwards.: https://ibb.co/MhJmxX4
In PA, all 5 sheds that report to Biobot are droping significantly!!: https://ibb.co/tPhVHWJ
And so are the Harrisburg and UPark areas which report to WastewaterSCAN. This is great for still having winter weather. We're handling it. We're doing something right!: https://ibb.co/5cWQDHh
The State PA Wastewater Dashboard now has many sheds, especially in the East, in the blue, SARS concentration lessening.: https://ibb.co/Wx2Pf2J
__________
Non-SARS2 Wastewater
OK, now for the not-so-great wastewater news: we're getting smashed by non-SARS pathogens like FluA, FluB, and Norovirus (which is the "24-hr stomach bug").
Numbers of FluA and FluB are rising significantly in all sheds that report to WastewaterSCAN.
FluA: https://ibb.co/Xkn6xYL
FluB: https://ibb.co/84wfBH9
Especially in UPark with FluB, yikes. Please wear a quality respirator to control this. Not doing so means more learning loss!
UPark is getting hit hard with Norovirus, which is already at HIGH levels and is going vertical there.: https://ibb.co/svpJB1t
C'mon, UPark, get a hold of this so your Spring won't be a mess! 💐
:ms_arrow_right: WASH hands, WASH food you eat and don't prepare food if you are sick to prevent the spread of Noro. It's just gross. Don't spread it!
It's still going to take a bit of work but if we do, we'll be more prepared for a healthier Spring.
And that in both scenarios: if we have a relatively calm COVID Spring with no new crazyfast variant (less likely), and also we won't be fighting pathogens on many different fronts if we DO have a crazyfast variant (more likely).
Stay healthy and have a great March! ❄️💐❄️
#covid #Covid19 #SARS2PA #CDC #CovidIsNotOver #Pennsylvania #PA #JN1 #JN1Eleven #JN1Eleven1 #JN1Sixteen #JN116 #KP1 #FluA #FluB #Influenza #Norovirus #Noro
#WearAMask #CleanTheAir #VaccinesSaveLives #Wastewater #StayHomeIfSick #SourceControl #USESourceControl #COVIDSourceControl
Dublin was gorgeous this morning. #photography #shotonNexus6P (if iPhone can do it so can we) #vsco #KP1 #Dublin
