Precise deletion, replacement and inversion of large DNA fragments in plants using dual prime editing.
#GenomeEditing #Plants #PrimeEditing
https://www.nature.com/articles/s41477-024-01898-3

Scientists are getting closer to treating the underlying causes of diseases like cystic fibrosis...

"We are hopeful that the use of prime editing to correct the predominant cause of cystic fibrosis might lead to a one-time, permanent treatment for this serious disease," said Professor David Liu.

#genetics #CysticFibrosis #health #medicine #disease #biology #research #PrimeEditing

https://www.labroots.com/trending/genetics-and-genomics/27415/gene-editor-correct-common-cystic-fibrosis-mutation

Eli Lilly’s growth drivers, Verzenio and Jardiance, suffer clinical setbacks—Prime editing comes of age as FDA clears human trials —Novartis pays PeptiDream $180M as radiopharma big bang continues--http://bit.ly/w28kSd #elililly #jardiance #earnings #primeediting #fda #clinicaltrials #novartis #radioligand #radiopharmaceuticals #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake
#Health #Science #DNA #Genetics #Genome #CAS9 #CRISPR #Proteins #GeneticDiseases #DNARepair #PrimeEditing #Mutations #MedicalResearch #ProteinDelivery #GeneticResearch
https://the-14.com/genetic-diseases-how-scientists-are-working-to-make-dna-repair-almost-a-piece-of-cake/

3rd ARRIGE Albrecht Müller Seminar (free online conference) on ‘Human Therapeutic Applications of Gene Editing’ November 13th, 2023 – 2pm-5pm (CET) – Paris time.
#CRISPR #GenomeEditing #ClinicalTrials #BaseEditing #primeediting #crisprcas9 #genetherapy #advancedtherapies #ARRIGE #ResponsibleResearch #ethics #bioethics #rri #innovation
Full information and registrarion link to gain free access to this meeting available at:
https://www.arrige.org/portfolio/3rd-albrecht-muller-arrige-seminar/

#PrimeEditing is a new #GenomeEditing technology that promises to fix #SickleCellDisease-causing mutations in a curative approach. Discover more about this technology, a collaboration of #StJude and the #BroadInstitute of MIT and #Harvard. https://bit.ly/3A5CbOP

Genuinely impressed by the creativity of #openai #gpt3. 🤯

What a great poem about #primeediting.
#CRISPR

Very interesting new review on #PrimeEditing out now in #NatureReviewsGenetics. Seems like a fast-moving technology with a lot of promise in fields like #medicine and agriculture, where making precise #DNA edits could be highly useful: https://www.nature.com/articles/s41576-022-00541-1 #science

"#primeEditing enzymes don’t have to break both strands of DNA to make changes, freeing researchers to make the edits that they want. could enable the development of treatments for genetic diseases that aren’t addressed by existing gene-editing tools."
https://www.nature.com/articles/d41586-019-03164-5?utm_source=twt_nnc&utm_medium=social&utm_campaign=naturenews&sf222231579=1