Eli Lilly Reports 29% Body Weight Reduction in Obesity Trial
Eli Lilly's obesity treatment demonstrated a 29% reduction in patient body weight according to recent trial results. The data strengthens the US pharmaceutical company's position in the expanding obesity therapeutics market, supporting continued growth in this business segment.
Readability Optimization in Uro-Oncology Trials: lol
📈 73.3 average readability mark
👨🏫 Middle-school reading level
✅ 100% content guideline adherence
#Pub2Post #AI #Urology #ClinicalTrials
tnyp.me/4pnAprii/m
The BRIDGE-AI 8 Study focused on improving readability in clinical trial summaries:
📝 Improved readability to FRES 73.3±3.5
📚 Aligned with middle school reading levels
🗂 Achieved 100% content inclusion
🔍 Enhanced comprehension
The BRIDGE-AI 8 Study focused on improving readability in clinical trial summaries:
📝 Improved readability to FRES 73.3±3.5
📚 Aligned with middle school reading levels
🗂 Achieved 100% content inclusion
🔍 Enhanced comprehension
Readability Optimization in Urological Oncology Trials:
• 📈 GAI tool Pub2Post improved readability in 20 trials.
• 📉 Reading level aligned with middle-school grade.
• 💯 Achieved 100% inclusion of guideline content.
• 📊 FRES score soared to 73.3 from 17.0.
RE: https://mastodon.social/@rstatsblazeemail/115685976251613412
For #clinicaltrials and #rstats - this is a big deal - CSRs (Module 5 in an eCTD) can now contain R packages within zip files (and html files - for WASM/Shiny?) and it looks like binary R package files for Modeling and Simulation Reporting. This gets around a key issue submitting non-published R packages to the FDA.
Flerie portfolio company AnaCardio reports strong Phase IIa results
AnaCardio has reported positive results from a clinical Phase IIa study of its lead drug candidate, AC01, tested in patients with heart failure. The data supports continued development of the treatment for cardiac conditions.
Hemab Therapeutics Reports Positive Phase II Data for Sutacimig in Glanzmann Thrombasthenia
Hemab Therapeutics announced positive Phase II results from the CL-101 study of sutacimig for prophylactic treatment of Glanzmann thrombasthenia. Data presented at ASH 2025 showed clinically meaningful efficacy across bleed locations, types, and dose cohorts. The company plans to advance to Phase III.
The FDA has qualified AIM-NASH, the first AI histology tool used as a drug-development endpoint, to read liver biopsies in MASH trials. What happens when an algorithm helps decide if a drug works?
https://biotech.industryexaminer.com/fda-aim-nash-ai-liver-biopsy-mash-trials/
#biotech #AIinBiotech #liverdisease #MASH #digitalpathology #clinicaltrials #regulatoryscience #TechNews
Looking for new hope beyond standard care?
China is leading the charge in advanced clinical trials for lung, gastric, and liver cancers. Faster access to ADCs and bispecifics is changing the landscape of Medical Tourism China.
As a medical concierge provider, MedBridgeNZ connect you to those who can.
Read why patients are looking East: https://zurl.co/2imnL
#ClinicalTrials#CancerCare #China #MedicalConcierge #MedBridgeNZ #MedicalTourismChina #ChinaMedicalTourism
A milestone! FDA expands accepted R file formats, resulting directly from joint work between industry and FDA through the R Consortium Submissions Working Group.
FDA expands accepted eCTD file formats for R packages
Newly accepted formats for R packages now include:
.rds, .rdb, .rdx, .rdata / .rda
.md, .rd
Expanded use of .zip and .html for delivering full R packages.
Details: https://r-consortium.org/posts/expanded-fda-ectd-file-format-support-for-r-packages
#rpharma #fda #regulatory #clinicaltrials #biostats #opensource
(04 Dec) 12 former FDA chiefs unite to say agency memo on vaccines is deeply stupid https://s.faithcollapsing.com/ambme #cdc #clinical-trials #covid-19 #fda #health #science #vaccines #vinay-prasad
12 former FDA chiefs unite to say agency memo on vaccines is deeply stupid https://arstechni.ca/AFhs #clinicaltrials #vinayprasad #COVID-19 #vaccines #Science #Health #CDC #fda
What causes Long COVID? @virusesimmunity.bsky.social sets out 4 hypotheses that remain highly plausible, backed by many studies. The challenge now: the right trials, with the right drugs, for the right duration.
#LongCOVID #Research #ClinicalTrials #PublicHealth
🔗 https://medicine.yale.edu/news-article/quick-question-do-we-know-what-causes-long-covid/
Focus group participants (n=25) from UK #ClinicalTrials units
rated for randomisation (lack of) predictability as more important than balance btw trial arms (can be adjusted for)
and different randomisation practices can be explained by unit practice:
https://link.springer.com/article/10.1186/s13063-024-08005-z
India’s AI adoption jumps to 86%, and TCS rolls out a new AI platform to streamline clinical trial oversight, aligning with ICH E6(R2) standards. Backed by Zinnov insights and led by Karthik Padmanabhan, the solution promises faster, compliant trials across GCCs. Curious how this could reshape pharma R&D? Read more. #AI #ClinicalTrials #TCS #Zinnov
🔗 https://aidailypost.com/news/tcs-launches-ai-platform-trial-oversight-indias-ai-use-rises-86-from
Africa: Phase 2 Clinical Trial Results Show Potential to Shorten TB Treatment Time: [TB Alliance] Sorfequiline, previously known as TBAJ-876, was evaluated in combination with pretomanid and linezolid in a randomized, controlled trial in people with drug-sensitive TB http://newsfeed.facilit8.network/TPLk4H #TB #Tuberculosis #ClinicalTrials #MedicalResearch #HealthInnovation
Can we edit cholesterol once and be done for life?
New phase 1 data on CTX310, a CRISPR-based infusion from @CrisprTx, show ~50% drops in LDL & triglycerides after a single dose on top of usual therapy.
Read the full analysis:
https://biotech.industryexaminer.com/one-time-crispr-edit-cholesterol-ctx310/
#CRISPR #GeneEditing #Biotech #Cholesterol #LDL #Cardiology #ClinicalTrials #HealthEconomics #PrecisionMedicine #TechNews
