🐁 Can we replace animal testing in inhalation toxicology with precision-engineered in vitro systems?

🔗 Application of the market-ready NAVETTA electrodeposition chamber for controlled in vitro exposure with nano-scaled aerosols. DOI: https://doi.org/10.1016/j.csbj.2024.12.008

📚 CSBJ Nanoscience and Advanced Materials: https://www.csbj.org/nano

#InVitroToxicology #Nanotechnology #AerosolScience #3Rs #SSbD #NAVETTA #Nanomedicine #PulmonaryResearch #InhalationToxicology #Nanotoxicology #NanoSafety #InVitroTesting

🐾 On #WorldAnimalDay, find out how new IHI project VICT3R plans to dramatically cut the use of animals in research - they will use existing data and #ArtificialIntelligence to create virtual control groups that could replace real animals in drug and chemical safety studies.
👉 https://europa.eu/!WPWDR6
#IHITransformingHealth #HorizonEU #3Rs #health #research

📰 Our September newsletter is out now at https://europa.eu/!6HxqxF
📢 News on our next call for proposals
✅ The newly-published evaluation of IMI2 and IHI
🐾 IMI project VAC2VAC's role in a 'historic' #3Rs decision to drop a common animal test
💔 BigData@Heart found that fitness trackers can provide useful info for people with #HeartDisease
👩‍🔬 How public-private partnerships are key to the fight against #AntimicrobialResistance
👋 We meet new project IHI-SYNTHIA
#IHITransformingHealth #HorizonEU

🐇 A 'historic' decision to drop a common animal test for contaminants in batches of medicines administered by injection was driven in part thanks to evidence from IMI project VAC2VAC, which demonstrated that non-animal alternatives are up to the job!
👉 https://europa.eu/!NG4XBk
#3Rs #IHITransformingHealth #HorizonEU

Finnish #3Rs center https://fin3r.fi/en is continuing with the webinars - on Jan 15th at 1 pm CET, Dr. Esther Pearl from https://www.nc3rs.org.uk/ will talk about Robust experimental design with the Experimental Design Assistant (EDA). Register for the webinar at https://helsinki.zoom.us/meeting/register/u5Eld-GspjIiEtahaijnK9tmofWAZaPCgttC

⏰ The deadline for IHI call 5 is just 4⃣ weeks away!
Topics: #3Rs #Theranostics #Stroke #SyntheticData
Got questions?
👓 Read the call text: http://europa.eu/!BxrRWT
📺 Watch the webinars: http://europa.eu/!MgwkBJ
Good luck! 🍀🍀🍀

⚠️The #EPAA3Rs has extended its deadline for the 2023 Refinement Prize!
💻 Submit your proposal by 25 September 👉https://europa.eu/!ygkB4J
🧪 Lab technicians, technologists and animal caretakers are all welcome to apply (➕ postdocs and master's/PHD students) 🐁
#3Rs

🐦🔗: https://n.respublicae.eu/EU_Growth/status/1704420140270362781

#MondayMotivation: ➡️ Apply to our calls! Wanted: #InnovativeSolutions on: ♻️ greening healthcare & #MedTech via #GreenChemistry & #PharmaPackaging, 🐾 #3Rs, inclusive #ClinicalTrials, #Theranostics, stroke research, blood sampling & more.
👉 Find out more: https://europa.eu/!FNknmv

RT @CCAAM_CaCVAM: Incredibly inspiring week at #ECVAM JRC Summer School on Non-Animal Approaches in Science! Young scientists from 31 countries already thinking outside the cage give so much hope for advancing #alternatives and the #3Rs for a future without animal testing! #Science #innovation https://t.co/MqyFhnbH2u

🐦🔗: https://n.respublicae.eu/EU_ScienceHub/status/1662714648745967618

📜 Call for submissions - deadline 5 June  ⌛️

The @EPAA3Rs is offering grants for #students to attend @EUROTOX2023 and @WC12Canada! Don't miss this chance to showcase your work on the #3Rs for alternatives to #animaltesting 👇

https://single-market-economy.ec.europa.eu/calls-expression-interest/3rs-student-grants-2023_en

🐦🔗: https://n.respublicae.eu/EU_Growth/status/1662411188548825088

🗓️ Save the date!

EMA is committed to replace, reduce, refine (#3Rs) #animaltesting in the development of human & veterinary medicines.

Interested in #AnimalWelfare? Join us online on 28 Feb, 9:00 - 9:45, to learn more on the Agency's work in this field & share your views.

🐦🔗: https://n.respublicae.eu/EMA_News/status/1627972847745245186

Do you #supervise #undergraduate or #Masters projects?
Interested in developing non-animal #research methods and #replacement of #animals in #animalresearch?
@FRAMEcharity offers small
#grants for:
📆 6–10 wks
💷 £350 per wk stipend
🔬 Up to £1000 consumables

#3Rs #NAMs #humanescience ⬇️⬇️⬇️

https://frame.org.uk/what-we-do/summer-studentship-programme/

Are you an #undergraduate or #Masters student? Interested in development of non-animal #research methods and #replacement of #animals in #animalresearch?

We offer small #grants for📆 6–10 weeks
💷 Stipend: £350 per week
🔬Consumables: Up to £1000 max

#3Rs #NAMs #humanescience ⬇️⬇️

https://frame.org.uk/what-we-do/summer-studentship-programme/

Our Honor cofounder @drcrystalheath@twitter.com spoke at @UWMadison@twitter.com on the Ethical Considerations in Dog Experimentation. We had members of the research community there as well, and it was a great discussion. Would you host a panel discussion at your school? https://youtu.be/fGZ-vzQjxuM #3rs

Animal Welfare Information Center (AWIC) at USDA is hiring a #librarian - looking for a recent graduate to support literature searching and evidence-based reviews on veterinary science, animal welfare, biomedical research https://www.usajobs.gov/job/700154300 #3Rs #AnimalWelfare #libraryjobs

FDA no longer needs to require #animaltests before human drug trials

"In place of the 1938 stipulation that potential drugs be tested for safety and efficacy in animals, the law allows FDA to promote a drug or biologic—a larger molecule such as an antibody—to human trials after either animal or nonanimal tests."

#AnimalResearch #3Rs #HumaneScience

https://www.science.org/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials

If #Insects are indeed #sentient, what would that mean for #animalwelfare law, and how we treat them in #farming, at home, in #research? Should we extend extend #AnimalWelfare Act 2006, so insect farms minimising suffering and use #humaneslaughter?.

What about Animals in Scientific Procedures Act? Like protecting octopuses should we regulate insect research, apply #3Rs and #ethics?

https://theconversation.com/insects-may-feel-pain-says-growing-evidence-heres-what-this-means-for-animal-welfare-laws-195328

My #introduction - researcher at the University of Helsinki, Finland interested in improving #preclinical research: #reproducibility and #3Rs via networking with other scientists in the field: https://www.cost.eu/actions/CA20135/
https://www.cost.eu/actions/CA21139/
https://fin3r.fi/en
https://www.finnish-rn.org/
https://quality-preclinical-data.eu/

Travelling home after a fascinating few days in Bern for the launch of the #Advancing3Rs #NRP79 from the SNSF. Great to hear all the interdisciplinary & innovative #3Rs projects just starting and help facilitate conversations about implementation from the outset #AnimalResearch #AnimalWelfare #3Rs
In closing discussions we talked about how to sustain communication between projects, here or elsewhere, so this is an experiment to see what engagement might follow.

Rethink #farm #animal #production: the #3Rs [#Replacement, #Reduction, #Refinement]

"70 billion terrestrial animals and between 59 and 129 billion aquatic animals are used annually, compared with 192 million #research animals [~670 times less animals]. However, animal #farming is not scrutinized through the lens of the 3Rs and instead remains focused on increasing production to feed the world. The justification for this #ethical discrepancy is unclear."

https://www.science.org/doi/10.1126/science.adf3351