Postdoctoral Research Scientist
Earlham Institute
Applications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK.
See the full job description on jobRxiv: https://jobrxiv.org/job/earlham-institute-27778-postdoctoral-research-scientist-7/?feed_id=95918
#bioinformatics #computational_biology #computational_ge...
https://jobrxiv.org/job/earlham-institute-27778-postdoctoral-research-scientist-7/?feed_id=95918
Discover the power of the All of Us annotator with Open Cravat! This tool leverages the vast allele frequency data from the All of Us Research Program, offering insights into genetic variations across diverse populations. By using this annotator, researchers can delve into non-European genetic diversity and advance precision medicine. Let's drive innovation in healthcare together! #PrecisionMedicine #Genomics #AllOfUs #OpenCravat#annotator #bioinformatics #opensource
🚨 Seeking a brilliant postdoc for a Marie Skłodowska-Curie Fellowship! Work at the interface of bioinformatics, evolution & biotech.
🌱 Join a top German university
💡 Great science, strong mentoring
👉 https://www.izmb.uni-bonn.de/en/pbb/contact
#MSCA #Postdoc #Biotech #Bioinformatics #AcademicJobs
@PuckerLab
Quadram Early Career Fellowship
Quadram Institute Bioscience
We have an exciting opportunity for Early Career Researchers to join a fellowship scheme to help individuals become future leaders
See the full job description on jobRxiv: https://jobrxiv.org/job/quadram-institute-bioscience-27778-quadram-early-career-fellowship/?feed_id=95862
#bioinformatics #genetics #gut_microbiome #micr...
https://jobrxiv.org/job/quadram-institute-bioscience-27778-quadram-early-career-fellowship/?feed_id=95862
🧬 New review out in Drug Discovery Today:
🔗 https://doi.org/10.1016/j.drudis.2025.104382
We take a critical look at how AI — especially AlphaFold(-Multimer/3) — has changed protein complex prediction.
End-to-end models work well for rigid complexes. Flexibility, disorder, and transient interfaces remain unsolved.
AI is shiny. Biology is complicated. We map what’s working, what isn’t, and what’s next.
#ComputationalBiology #Bioinformatics #DrugDiscovery #AlphaFold
🐶 New preprint: DoggifAI
🤖 We built a transformer model that translates antibodies from mouse/human to dog “protein language” - preserving structure while reducing immunogenicity.
📂 Open model, code + dataset of 430k canine antibody sequences (largest to date): https://www.biorxiv.org/content/10.1101/2025.05.28.656573v1
#bioinformatics #AI #immunotherapy #OpenScience #preprint #comparativeoncology #dogs #OpenData, #cancerresearch
New preprint: we used k-mer matching with suffix match length information to create an assembly-to-assembly alignment algorithm + software for bacterial genomes, kbo.
kbo uses the SBWT data structure which lets us run a query in 1-10s and 500-1000MB RAM, depending on the task and parameters.
All our algorithms run in the browser, try the tool at maklin.fi/kbo/ There is no server-side processing, so the data never leaves your computer.
link: https://www.biorxiv.org/content/10.1101/2025.05.19.654936v2
Doing #Bioinformatics #Scicomm today to elementary school children.
Between the pictures, I have a terminal running analysis.
The first question was "Are you a Hacker?", and the second: "Can you make the letters green?"
The kids are alright. =-)
In fact, bioinformatics is concerned with something extremely tangible - the biomolecular systems - wetware - that makes up people's bodies. #bioinformatics #wetware
I decided that in order to make bioinformatics relatable, the informational content should be connected with some tangible objects, this is why I am making cupcakes. #bioinformatics
Bioinformatics has a problem: even if it is critical for humanity development, the public explanation "why it is so" seems hard or impossible task. Obscurity and hightech/deeptech status is responsible. #bioinformatics
#htslib #Bioinformatics #GenomicsIO
@yokofakun any idea what is the fastest method to get the nth bcf record using htslib or bcftools.h without explicit loops? (trying out something similar to your project https://github.com/lindenb/rbcf but with ALTREP)
I guess it is possible to guess which block to (lazy) parse if one know the blocks offsets and number of records per block
Providing training in the field of bioinformatics is critical for new anti-cancer drugs development, among other therapeutic applications. #bioinformatics #bioinformaticstraining
🧬 Could the grammar of DNA be unraveled using tools from natural language processing?
🔗 A review on the applications of Transformer-based language models for nucleotide sequence analysis. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.03.024
📚 CSBJ: https://www.csbj.org/
#Bioinformatics #AIinBiology #Transformers #Genomics #NLP #DeepLearning #PrecisionMedicine #TransformerModels #DNABERT #ComputationalBiology
Pipeline release! nf-core/multiplesequencealign v1.1.1 - nf-core/multiplesequencealign v1.1.1 - Bogatell!
Please see the changelog: https://github.com/nf-core/multiplesequencealign/releases/tag/1.1.1
📝 New Bioconductor Blog Post!
We’ve just launched the first in a new series by Vince Carey, founding contributor to Bioconductor and core developer, exploring the evolving complexity and value of the Bioconductor ecosystem.
Check it out 👉 https://blog.bioconductor.org/posts/2025-05-26-ask
#Bioconductor #RStats #Bioinformatics #DataScience #OpenScience
Today at the German Cancer Research Congress (#GCRC2025) at
@DKFZ in Heidelberg, GHGA is showcasing its work on secure and FAIR genomic data sharing at our booth and poster.
Stop by to learn more.
John Lennox and Systems Biology: A Misuse of Complexity? (Alex O’Connor)
#bioinformatics #systemsbiology #atheism
https://www.youtube.com/watch?v=51AfW2MOM8A
Anyone have any recommendations on a free online short course that they have found useful in the fields of #bioinformatics #genomics #agriculture #rstats or related?
