@trendless Some context I had to look up for https://www.cell.com/heliyon/fulltext/S2405-8440(25)00579-1
in their intro they say "One of the most important case-study explanation on how COVID-19 is involved in neurological manifestations is that SARS-CoV-2 can accelerate the pathogenesis prion disease by decreasing the glia including astrocytes homeostatic identities in a specific region in the CNS such as Creutzfeldt-Jakob disease and scrapie prions" which absolutely matches up with neuro papers
but amyloids? I didn't know, before now: "all amyloids could be considered prions" [1]
Huh. Well I didn't remember which diseases are amyloid-associated (and I know there's been controversy over Alzheimer's etiology), conveniently they say the "group of diseases ranges from neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), and human transmissible spongiform encephalopathies (TSEs), which are commonly known as prion diseases; to non-neurodegenerative systemic and localized amyloidosis, which include amyloid light-chain amyloidosis (AL) and type II diabetes" [1]
[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4601197/
#COVID #COVID19 #SARSCoV2 #AmyloidResearch #prions #CJD #neuroscience