Ah, the wonders of modern education: 🌟 a 3D animation showing DNA replication that’s perfect for middle schoolers who can’t get enough of Ötzi 🧊 and CSHL’s endless list of field trips. Because nothing says cutting-edge science like a glorified screensaver and a list of activities longer than the human genome itself. 🧬🎉
https://dnalc.cshl.edu/resources/3d/04-mechanism-of-replication-advanced.html #moderneducation #DNAreplication #3Danimation #scienceforkids #fieldtrips #HackerNews #ngated

The structure of the tetrameric GINS complex from S. solfataricus reveals a core structure highly similar to the previously determined GINS core structures of other eukaryotes and archaea #DNAReplication #GINS #MinichromosomeMaintenance https://doi.org/10.1107/S2053230X25003085

Scientists filmed DNA unzipping in real-time! This breakthrough could revolutionize cancer and virus treatment. #DNAReplication #CancerResearch #BiotechInnovation

https://geekoo.news/dna-unzipped-new-microscopy-breakthrough-paves-way-for-cancer-and-virus-therapies/

Molecular animations reveal DNA's unzipping mechanism: Implications for viral and cancer treatments
https://www.sciencedaily.com/releases/2025/03/250320144758.htm
https://le.ac.uk/news/2025/march/dna-helix-microscopy-cancer

* scientists captured 1st detailed 'molecular movie' showing DNA being unzipped at atomic level
* reveals how cells begin crucial process of copying their genetic material

Structural dynamics of DNA unwinding by a replicative helicase
https://www.nature.com/articles/s41586-025-08766-w#Sec25

#cancer #MolecularGenetics #StructuralBiology #DNAreplication #DNAhelicase

The crystal structure of proliferating cell nuclear antigen 1 from Aeropyrum pernix revealed that it does not form a trimeric ring, unlike those from other domains of life #ProliferatingCellNuclearAntigens #DNAReplication #AeropyrumPernix https://doi.org/10.1107/S2053230X24009518

 Understanding DNA Metabolism: A Complex Dance of Life

#DNA, #DNAMetabolism, #DNARepair, #DNAReplication, #Metabolis, #Tramsciption #Genetics DNA, the blueprint of life, holds the key to understanding the complexity of living organisms. Its structure, composed of nucleotide…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/15/understanding-dna-metabolism-a-complex-dance-of-life/

Unveiling the Hidden Secrets of Life through Bioinformatics

#Bioinformatics, #DNA, #DNAIsolation, #DNARecombination, #DNAReplication, #DNASeperation, #DNASequence, #Genomics, #StructuralBiology #Bioinformatics Introduction: In the age of information, the world of biology has undergone a revolutionary transformation. The decoding of the human…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/05/unveiling-the-hidden-secrets-of-life-through-bioinformatics/

Unraveling the Mechanisms: Regulation of DNA Replication in Bacterial Cells

#Bacteria, #CellCycle, #DNA, #DNAReplication, #DnaA, #OriC, #RegulatoryProteins, #Replication #Genetics, #MolecularBiology DNA replication is a fundamental process in all living organisms, ensuring the faithful transmission of genetic information from one generation to the next. In bacterial cells, where simplicity meets efficiency…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs…

https://micrordt.wordpress.com/2024/05/01/unraveling-the-mechanisms-regulation-of-dna-replication-in-bacterial-cells/

DNA Repair

#DNA, #DNARecombination, #DNARepair, #DNAReplication, #DNASequence, #Proofreading #Genetics DNA is  most important molecule for working of cell. Although it directly not take part in metabolic pathways, but it keep…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/04/29/dna-repair/

Effects of Mutations 

#DNA, #DNAReplication, #DNASequence, #Mutant, #Mutation #Genetics Mutation is the sudden change in the nucleotide sequence of DNA, they are not predefined i.e. a mutation may be…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/04/29/effects-of-mutations/

Mutations And Their Chemical Basis

#DNA, #DNAReplication, #Mutation #Genetics Mutations were initially characterized as altered phenotype, but they have now understood at the molecular level. Several types of mutation exist.…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/04/29/mutations-and-their-chemical-basis/

Patterns Of DNA Synthesis

#DNA, #DNAReplication, #DNASequence, #Fork, #Replication, #RollingCircle #Genetics Although, all form of living organisms show a common feature, DNA is the genetic material. But when we look for…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/04/28/patterns-of-dna-synthesis/

DNA Replication: Introduction

#DNA, #DNAReplication, #SemicaonservativeReplication #Genetics As we come to know that DNA is the genetic material, all show interest in knowing how it transfer information…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/04/28/dna-replication-introduction/

Jasmine Peake and Kalisse Horne, Drexel MCBG PhD students from the lab of Dr. Eishi Noguchi @enog published a nice paper about acetaldehyde-induced genomic instability 🤩
Great work, Jasmine and Kalisse 🎉
Please check!!!

Jasmine is currently an Assistant Professor at Lincoln University

#CancerBiology #BiomedicalScience #GraduateStudies #DNARepair #DNAReplication

https://www.tandfonline.com/doi/full/10.1080/15384101.2023.2261740

Referenced link: https://medicalxpress.com/news/2023-05-dna-replication-discovery-paths-cancer.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-05-dna-replication-discovery-paths-cancer.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1653803788359151618#m

RT by @physorg_com: #DNAreplication discovery opens paths to understanding and treating cancer, aging and degenerative disease @VanderbiltU @sciencemagazine https://www.science.org/doi/10.1126/science.add7328 https://medicalxpress.com/news/2023-05-dna-replication-discovery-paths-cancer.html

Referenced link: https://phys.org/news/2023-04-motor-dna-replication.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-04-motor-dna-replication.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1649044363819753472#m

Researchers shed new light on the motor of #DNAreplication @TUDelft @NatureComms https://www.nature.com/articles/s41467-023-37093-9 https://phys.org/news/2023-04-motor-dna-replication.html

Right on the heels of the @Fusion_Conf on Homologous Recombination in Portugal!!
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RT @mages05
Reg now open! Talk #Cancer #Aging #DNAReplication #Translation #GeneExpression at The Helicases and #Nucleic Acid-based Machines Conf. 7/16-20 #HNASRC

Abstracts Due: 5/14
Info: http://bit.ly/3JJ5hK1
Organizers: @bethtran76 @Trakselis @PaeschkeLab
Keynote: @PatrickSungLab https://twitter.com/taekjip/status/1575285593998622721
https://twitter.com/mages05/status/1621525464400420864

A fantastic recognition of these amazing scientists' contributions! 🥳
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RT @MRC_LMB
Congratulations to @KellyTHD_Nguyen, @bwfalcon and LMB alumni, @BolandLab_GE and @M_Hospenthal, for being elected @EMBO_YIP!

Read the full news story here: https://www2.mrc-lmb.cam.ac.uk/embo-announces-2023-elections-for-young-investigator-programme/

#LMBNews #LMBAlumni #telomeres #DNAreplication #neurodegenerative #diseases
https://twitter.com/MRC_LMB/status/1595060285261373443

Important new paper on #DNAreplication from Pierre Murat in Julian Sale's group at the LMB in Cambridge. Interestingly there is a clear signature of mutation surrounding replication origins in mammalian cells such that they mutate more rapidly than non-origin sequences. A consequence of this is presumably that origin of replication move around rapidly over evolutionary timescales (and potentially even in cancer evolution). Interesting from an evolutionary perspective as some eukaryotes (e.g. cerevisiae) have quite localised origins- maintaining these must require quite strong selection- why are localised origins important in some eukaryotes and not others? Link to paper is here:
https://www.science.org/doi/10.1126/sciadv.add3686