@FotoVorschlag
'Im (Bastel) Keller ' #FotoVorschlag

Nicht mein Bastelkeller, sondern die Werkstatt eines fabelhaften, genialen #Brompton Künstlers, des wunderbaren #BenCooper von #Kinetics in #Glasgow

So sah es 2016 bei meinem Besuch aus. Inzwischen hat er die Werkstatt nebenan dazu bekommen und etwas mehr Platz.

#LabPlot at the service of #researchers. :boost_love:

@labplot@lemmy.kde.social

It's rewarding to us to know that #LabPlot was used for the #drug release #kinetics investigation in this recent study on niosomal co-delivery of #metformin and #telaglenastat.

➡️ https://www.sciencedirect.com/science/article/pii/S0753332225010376

#Research #Science #OpenSource #FreeSoftware #FOSS #KDE #FreeOriginProAlternative #BreastCancer #Cancer #Cytotoxicity

@margraf
also #FediHire and #fedijobs and #Job and #Jobs
I would also recommend some hashtags related tobthe subject. #maschinelearning and #chemistry and #kinetics would be good subject appropiate ones.

I replaced vector databases with Git for AI memory (PoC)

https://github.com/Growth-Kinetics/DiffMem

#HackerNews #AI #Memory #Git #Vector #Databases #PoC #Growth #Kinetics

Interesting paper by the group of Peter Tonge in @jacs.acspublications.org. They studied the #kinetics of non-covalent #BTK inhibitors. Clinical compounds showed increased residence times, while association rates were nearly constant. pubs.acs.org/doi/10.... #Kinases #DrugDiscovery #ChemSky #ChemBio

Modulating the Binding Kinetic...

Interesting paper by the group of Peter Tonge in JACS. They studied the detailed kinetics of non-covalent BTK inhibitors. Interesting insights that clinical compounds showed increased residence times, while association rates remained nearly constant. https://pubs.acs.org/doi/10.1021/jacs.5c07063
#Kinases #DrugDiscovery #Chemistry #ChemBio #BTK #Kinetics

@velospinner: They're are exaggerating claiming "We made". Actually the #MTBrompton is "Ben Cooper made", they just assembled the kit (but yeah, they mention it, but then again, they don't link to his site): https://www.kinetics-online.co.uk/folding-bikes/brompton/the-mtbrompton/

But yeah, that's a great and hilarious #GCN episode.

You might also enjoy this #BermPeak episode where Seth of Berm Peak takes a standard #Brompton C-Line to a #skatepark 🤪: https://www.youtube.com/watch?v=TLg0NNjDBMQ

Spoiler: It survives. 😉

#BenCooper #Kinetics

this work is now published in ACS Electrochemistry at https://doi.org/10.1021/acselectrochem.5c00158

#compchem #electrochem #kinetics

Hello Mastodon!

#introduction

This is the official account for COPASI, the popular open source software for modeling and simulation of biochemical reaction networks

#SystemsBiology
#Chemistry
#Kinetics
#ChemicalKinetics
#ReactionNetworks
#Dynamics
#ComputationalModels

Characterising viral #clearance #kinetics in acute #influenza, https://etidiohnew.blogspot.com/2025/03/characterising-viral-clearance-kinetics.html

Viral #kinetics of #H5N1 #infections in dairy #cattle, https://etidiohnew.blogspot.com/2025/02/viral-kinetics-of-h5n1-infections-in.html

Our article on #HPV #kinetics is officially out in @PLOSBiology 📰

https://mastodon.social/@PLOSBiology@fediscience.org/113900903417651328

#Replication #Kinetics, #Pathogenicity and Virus-induced Cellular Responses of #Cattle-origin #Influenza A(#H5N1) Isolates from #Texas, United States

Source: BioRxIV, AbstractThe host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States. Shortly after, human H5N1 infection was reported in a dairy worker in Texas following exposure to infected cattle. Herein, we rescued the cattle-origin influenza…

https://etidioh.wordpress.com/2024/10/30/replication-kinetics-pathogenicity-and-virus-induced-cellular-responses-of-cattle-origin-influenza-ah5n1-isolates-from-texas-united-states/

#BenCooper aka #Kinetics posted a comparison table between his 20" #MTBrompton conversion and the new ex-works 20" #Brompton #G_Line: https://www.kinetics-online.co.uk/technical-info/g-line-vs-mtbrompton/

@insl: It's now on his website at https://www.kinetics-online.co.uk/custom-builds/recumbent-brompton/ and official: #BenCooper aka #Kinetics plans to offer a #Brompton FWD #recumbent kit in the future!

Citing from there:

"This, with some more development, will be a kit that you can add to your own Brompton – there’s no modification needed to the mainframe, it just replaces the front fork. Watch this space…"

There's even a video of unfolding it!

This solves at least the "problem" what to do with my current Brompton if I buy a G-Line. 😉

#Morphology-dependent #entry #kinetics and #spread of #influenza A virus, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.08.01.605992v1

We found that cellular junction integrity and mucin do not exert morphology-dependent inhibition of IAV cell-to-cell spread. On the other hand, filamentous #virions confer an advantage under the #pressure exerted by neutralizing #antibodies against #hemagglutinin.

#Assessment of #Survival #Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 #H5Nx Avian #Influenza #Viruses, Viruses: https://www.mdpi.com/1999-4915/16/6/889

Statistical tests of the difference between the DT values and extinction times of each clade 2.3.4.4 strain at each #temperature indicated that the majority displayed different survival kinetics from the other strains at 4 °C and 20 °C.

The #kinetics and optimality of #influenza A virus #locomotion http://biorxiv.org/cgi/content/short/2024.05.06.592729v1?rss=1

Our findings suggest novel therapeutic targets and provide insight into possible mechanisms of #zoonotic #transmission.

"Here, using operando optical microscopy, we image the local doping level of the #transistor channel and show that turn-on occurs in two stages—propagation of a doping front, followed by uniform doping—while turn-off occurs in one stage. We attribute the faster turn-off to a combination of engineering as well as physical and chemical factors including channel geometry, differences in doping and dedoping #kinetics and the phenomena of carrier-density-dependent mobility"

https://www.nature.com/articles/s41563-024-01875-3

Question for #Chemistry people - I’m looking at a HS text that states the following definition for “catalyst” is now “favoured”:

“A catalyst is a substance which provides an overall reaction with an alternative mechanism having a lower activation energy.”

I seem to recall that the alternative mechanism does NOT have to have a lower activation energy to increase the rate - just the possibility of another pathway will increase the rate.

(I notice that this definition doesn't mention the rate of the overall reaction at all.)

Would it suffice to say that a catalyst is a substance that provides an overall reaction with an alternative mechanism, and leave it at that? The regeneration of the catalyst seems to be assumed, and the rate will increase as a result of the extra pathway.

Eager to hear your (informed) opinions 😊

#Chemistry #Catalyst #Kinetics #ChemEd