Hello Mastodon!
This is the official account for COPASI, the popular open source software for modeling and simulation of biochemical reaction networks
#SystemsBiology
#Chemistry
#Kinetics
#ChemicalKinetics
#ReactionNetworks
#Dynamics
#ComputationalModels
Characterising viral #clearance #kinetics in acute #influenza, https://etidiohnew.blogspot.com/2025/03/characterising-viral-clearance-kinetics.html
Our article on #HPV #kinetics is officially out in @PLOSBiology 📰
https://mastodon.social/@PLOSBiology@fediscience.org/113900903417651328
#Replication #Kinetics, #Pathogenicity and Virus-induced Cellular Responses of #Cattle-origin #Influenza A(#H5N1) Isolates from #Texas, United States
Source: BioRxIV, AbstractThe host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States. Shortly after, human H5N1 infection was reported in a dairy worker in Texas following exposure to infected cattle. Herein, we rescued the cattle-origin influenza…
#BenCooper aka #Kinetics posted a comparison table between his 20" #MTBrompton conversion and the new ex-works 20" #Brompton #G_Line: https://www.kinetics-online.co.uk/technical-info/g-line-vs-mtbrompton/
@insl: It's now on his website at https://www.kinetics-online.co.uk/custom-builds/recumbent-brompton/ and official: #BenCooper aka #Kinetics plans to offer a #Brompton FWD #recumbent kit in the future!
Citing from there:
"This, with some more development, will be a kit that you can add to your own Brompton – there’s no modification needed to the mainframe, it just replaces the front fork. Watch this space…"
There's even a video of unfolding it!
This solves at least the "problem" what to do with my current Brompton if I buy a G-Line. 😉
#Morphology-dependent #entry #kinetics and #spread of #influenza A virus, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.08.01.605992v1
We found that cellular junction integrity and mucin do not exert morphology-dependent inhibition of IAV cell-to-cell spread. On the other hand, filamentous #virions confer an advantage under the #pressure exerted by neutralizing #antibodies against #hemagglutinin.
#Assessment of #Survival #Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 #H5Nx Avian #Influenza #Viruses, Viruses: https://www.mdpi.com/1999-4915/16/6/889
Statistical tests of the difference between the DT values and extinction times of each clade 2.3.4.4 strain at each #temperature indicated that the majority displayed different survival kinetics from the other strains at 4 °C and 20 °C.
The #kinetics and optimality of #influenza A virus #locomotion http://biorxiv.org/cgi/content/short/2024.05.06.592729v1?rss=1
Our findings suggest novel therapeutic targets and provide insight into possible mechanisms of #zoonotic #transmission.
"Here, using operando optical microscopy, we image the local doping level of the #transistor channel and show that turn-on occurs in two stages—propagation of a doping front, followed by uniform doping—while turn-off occurs in one stage. We attribute the faster turn-off to a combination of engineering as well as physical and chemical factors including channel geometry, differences in doping and dedoping #kinetics and the phenomena of carrier-density-dependent mobility"
Question for #Chemistry people - I’m looking at a HS text that states the following definition for “catalyst” is now “favoured”:
“A catalyst is a substance which provides an overall reaction with an alternative mechanism having a lower activation energy.”
I seem to recall that the alternative mechanism does NOT have to have a lower activation energy to increase the rate - just the possibility of another pathway will increase the rate.
(I notice that this definition doesn't mention the rate of the overall reaction at all.)
Would it suffice to say that a catalyst is a substance that provides an overall reaction with an alternative mechanism, and leave it at that? The regeneration of the catalyst seems to be assumed, and the rate will increase as a result of the extra pathway.
Eager to hear your (informed) opinions 😊
It’s five in the morning. I’m up and awake, on my first cuppa, and my glamorous assistant is being helpful. Thank you #Bjork #Bjorkthecat #Glamorousassistant #Catsandautimata #Kinetics #Sketchbook #Automata
#DogWalkingGeology from this morning. Here's a lovely wee layer of pale blue elongate kyanite crystals, pale pink elongate andalusite, plus some wee brown round garnets, in schist from Ardalanish Bay. Although the andalusite and kyanite look happy together, they are not actually in equilibrium: this layer has "frozen" during the slow process of converting kyanite to andalusite. Reactions are all about the kinetics! #Metastable #Mull #Moine #RossOfMullGranite #Geology #Minerals #Al2SiO5 #Kinetics
Long term anti- #SARS-CoV-2 #antibody #kinetics and correlate of #protection against #Omicron BA.1/ #BA2 infection https://www.nature.com/articles/s41467-023-38744-7
https://www.pnas.org/doi/10.1073/pnas.2217189120
"Stopped-flow measurements coupled with infrared and UV-visible detection reveal that the sole product of initial protonation of Cp*Rh(bpy) is [Cp*Rh(H)(bpy)]+, an elusive #hydride complex that has been spectroscopically and kinetically characterized here. Tautomerization of the hydride leads to the clean formation of [(Cp*H)Rh(bpy)]+."
#chemistry #chemicalReaction #reaction #mechanism #catalyst #catalysis #kinetics
Applications session: Talk
6. Ulrike Wittig introduces the SABIO-RK Database, a manually curated database for biochemical reactions and their kinetics, and explains about improved insights via visualization of data
#biocuration2023 #Applications #biochemicalreactions #kinetics
