#EnzymeEngineering

2025-01-16

Engineering a Decarboxylative Aldolase for the Synthesis of Cyclic Imino Acids:
Divergent regioselectivity and diastereoselectivity compared to the wild-type enzyme achieved
chemistryviews.org/engineering

#biocatalysis #enzymeengineering #chemistry #chemistryviews #chemviews

2023-01-03

Excited to share my very first paper which was just published in #JACS:

pubs.acs.org/doi/10.1021/jacs.

In this work carried out during my PhD together with Jamie Klein, Tomasz Kaminski, and Pierre-Yves Colin in the Hollfelder Lab at #UniversityofCambridge we evolve a #phosphotriesterase with a new, metal-independent mechanism by using droplet #microfluidics.

Comments and feedback welcome! A thread: (1/6)

#EnzymeEngineering #ProteinEngineering #EnzymeMechanism #DirectedEvolution #Bioremediation

Folmerfolfdk
2022-12-16

David Bakers talk
"The coming of age of de novo protein design" at the NIH from Dec. 14th

@strucbio

videocast.nih.gov/watch=46050

Folmerfolfdk
2022-12-14
Folmerfolfdk
2022-12-03

on

This is kind of fun.

But also there are some obvious limitations. Still shallow waters.

Generated by chat.openai.com
With the prompt:
"Write a poem on enzyme engineering"

Enzyme engineering, A field of endless possibilities, Creating solutions.

With skill and precision, Scientists design and build, Enzymes for the world.

From medicine to industry, These biological catalysts, Speed up reactions.

A wonder of biotechnology, Enzyme engineering, Paving the way for the future.

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