Lmst

The 4th edition of the Integrative Structural Biology Meeting (#BSI), co-organized with the Association Française de Cristallographie (#AFC) and the Société Française de Biophysique (#SFB) will be held in Bordeaux 15th-19th of December 2025. Scientific sessions will cover a wide range of scientific research in the fields of #StructuralBiology , #Biophysics and #StructuralBiochemistry.
More information ➡️ https://bsi4.org/
@cnrs @afmblab.bsky.social @strucbio @ActaCrystF

🧬 When does molecular dynamics improve RNA models? Insights from CASP15 and practical guidelines. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.003

📚 CSBJ: https://www.csbj.org/

#RNA #StructuralBiology #CASP15 #ComputationalBiology #Bioinformatics #MolecularSimulation #MolecularDynamics #Biophysics #MolecularModeling

When does molecular dynamics improve RNA models? Insights from CASP15 and practical guidelines. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.003

🦠 What makes antimicrobial peptides so selective against bacteria and cancer cells, while leaving healthy cells intact?

🔗 Unlocking the specificity of antimicrobial peptide interactions for membrane-targeted therapies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.04.022

📚 CSBJ Nanoscience & Advanced Materials: https://csbj.org/nano

#AntimicrobialPeptides #DrugDiscovery #MolecularDynamics #Biophysics #MembraneBiology #Bioinformatics #PeptideTherapeutics

Unlocking the specificity of antimicrobial peptide interactions for membrane-targeted therapies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.04.022

Meet Ré Mansbach PhD, Associate Professor in the Department of Physics at Concordia University, and Tier II Canada Research Chair in Computational Biophysics, whose lab uses computers to understand how proteins work.

https://www.youtube.com/watch?v=OQ9R3kSjaqM

#ConcordiaHealth #ConcordiaUniversity #biophysics #proteins #AI #MDsimulations #physics #artificialintelligence #machinelearning #deeplearning

⚛️ Could quantum physics explain how consciousness arises in the brain?

🔗 Conscious active inference II: Quantum orchestrated objective reduction among intraneuronal microtubules naturally accounts for discrete perceptual cycles. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.016

📚 CSBJ Quantum Biology & Biophotonics: https://www.csbj.org/qbio

#Consciousness #Neuroscience #QuantumBiology #QuantumPhysics #CognitiveScience #BrainResearch #Neurotechnology #Biophysics

Conscious active inference II: Quantum orchestrated objective reduction among intraneuronal microtubules naturally accounts for discrete perceptual cycles. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.016

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=2699

CMCB people: the lab talks are back for new academic year!

We have Darius Koester today:

Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton

1pm T0.08/09

#biophysics

Postdoctoral Associate in Membrane Protein Structural Biology
Vecchio Lab at University at Buffalo

#postdoc in vecchio lab at university at buffalo department of #structuralbiology studying #membraneprotein #structureandfunction

See the full job description on jobRxiv: https://jobrxiv.org/job/university-at-buffalo-27778-postdoctoral-associate/

#biophysics #cryoEM #membraneproteins #proteinproteininter...
https://jobrxiv.org/job/university-at-buffalo-27778-postdoctoral-associate/?fsp_sid=2412

Are robots fit for the future of recycling?

It turns out recycling a range of textiles, cables, and many other fiddly materials is tough for automated machines. To develop solutions, an international research team including our Uni have been awarded funding for their #FlexCycle project as part of the EU’s #GreenDeal programme: https://www.uni-goettingen.de/en/3240.html?id=7898

Twelve project partners from research and industry working together to develop new software, flexible robotic grippers and other multi-functional robotic tools #Biophysics #NeuralNetworks

Photograph showing a tangle of wires and cables in yellow, blue, red, dark grey. There are bits of white plastic holding some of the cables into groups but it looks like a complicated mess. Image thanks to Nathan Cima on Unsplash.

The final version of our review on biological filaments is out in Philtrans A (w/@jcammann.bsky.social Hannah Laeverenz-Schlogelhofer & Marco Mazza) - we have 417 references! Enjoy :) doi.org/10.1098/rsta... (see also other articles in this special issue on biological fluid dynamics) #biophysics

THE EXPERT EDGE BY ZPONZ: Expert in BioPhysics
Dean of the Faculty of Science at Ryerson University and Professor in the Department of Chemistry & Biology. Dr. Coe is an award-winning scientist who continues to conduct research into enhanced understanding drug transport proteins involved in the uptake of anti-cancer, anti-viral and anti-parasite drugs.
#ZPONZ #GetPaidForExpertise #MonetizeYourSkills #BioPhysics

Postdoctoral Associate in Membrane Protein Structural Biology
Vecchio Lab at University at Buffalo

#postdoc in vecchio lab at university at buffalo department of #structuralbiology studying #membraneprotein #structureandfunction

See the full job description on jobRxiv: https://jobrxiv.org/job/university-at-buffalo-27778-postdoctoral-associate/

#biophysics #cryoEM #membraneproteins #proteinproteininter...
https://jobrxiv.org/job/university-at-buffalo-27778-postdoctoral-associate/?fsp_sid=1950

Post-Doctoral Fellowship in Structural Biology
Biology of Bacteria and Bacteriophages Research Centre

See the full job description on jobRxiv: https://jobrxiv.org/job/biology-of-bacteria-and-bacteriophages-research-centre-27778-post-doctoral-fellowship-in-structural-biology-2/

#biophysics #Nuclearmagneticresonance #ScienceJobs #hiring #research
https://jobrxiv.org/job/biology-of-bacteria-and-bacteriophages-research-centre-27778-post-doctoral-fellowship-in-structural-biology-2/?fsp_sid=1901

🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?

🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria

Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=1628

⏰ Body clock keeps 24-hour rhythm by distorting gene activity in the heat

... the linked paper has "Renormalization Group" in the title which is something I'm always for even if it is only a semigroup

https://medicalxpress.com/news/2025-07-body-clock-hour-rhythm-distorting.html

#biology #physics #biophysics #math #circadian #time #molbio #renormalizationgroup

Now published... and on the #BiophysJ cover!

Cell Adhesion Pattern Shows Conserved #Scalings under #Geometrical Control

Studying the relationship between the size and the #anatomy and #physiology of #living #organisms has proven useful in deciphering what the key physical constraints are that apply to them. For instance, total adhesive pad area is found to #scale like organism mass over a wide variety of animal species, possibly to resist against body weight.

In this study, we apply this approach at the cell scale to ask how large-scale geometrical constraints affect the organisation of #adhesion patches and the size of #cellSubstrate contact at different stages of the #cellSpreading process. Indeed, #cells, like many animals, adhere to their substrate. For that, they use specific protein complexes, called #focalAdhesions, which form patches often situated at the cell periphery.

cc @JonFouchard

https://www.biophysics.org/blog/cell-adhesion-pattern-shows-conserved-scalings-under-geometrical-control

#cellAdhesion #biophysics #allometry

🧬 Just out in Biophysical Reviews:

“Machine learning interatomic potentials in biomolecular modeling: principles, architectures, and applications”
🔗 https://doi.org/10.1007/s12551-025-01351-5 MLIPs combine efficiency of force fields with quantum accuracy — now entering structural biology & computational drug discovery.
#OpenScience #Biophysics #MLIPs #MolecularDynamics #MachineLearning