Lmst

Synthetic Biology for Light-Activated Smart Materials

Design and characterise light-responsive proteins and demonstrate light-controlled behaviour of cell-free biology in materials.

#SynBio, #StructuralBiology, #ProteinEngineering, and #biomaterials.

#PhD Studentships are fully funded for 4yrs, with minimum of 3 months at the industry partner. Funding for home (UK) students = tax-free stipend (indicative in year 1 in 2026-27 (£21,383), research costs and tuition fees.
https://www.findaphd.com/phds/project/synthetic-biology-for-light-activated-smart-materials/?p193808

How I Built a Machine Learning Tool to Predict Drug Manufacturing Failures

A bioprocess engineer's journey into machine learning and why the pharmaceutical industry desperately needs this bridge When I tell people I work in bioprocess engineering, I usually get blank stares. When I explain that I help manufacture proteins in giant tanks for therapeutic use, the response is often: "Oh, like brewing beer?" Not quite. But close enough. What I don't usually mention is that I've been teaching myself machine learning on nights and weekends. Not because it's trendy, but […]

https://kemal.yaylali.uk/from-bioreactors-to-ai-how-i-built-a-machine-learning-tool-to-predict-drug-manufacturing-failures/

Inito Secures $29M to Build Next-Gen AI-Engineered Home Diagnostics

#NewsUpturn #Inito #SeriesBFunding #HealthTech #AIinHealthcare #AtHomeDiagnostics #AIDiagnostics #DigitalHealth #FemTech #FertilityTech #BiotechInnovation #ProteinEngineering #SyntheticAntibodies #BertelsmannIndiaInvestments #FiresideVentures #StartupFunding #HealthcareInnovation #HormoneHealth #MedicalAI #IndiaStartups #DeepTech #HealthMonitoring #ConsumerHealthTech

https://newsupturn.com/inito-secures-29m-to-build-next-gen-ai-engineered-home-diagnostics/

Inito Raises $29M Series B to Advance AI-Powered At-Home Diagnostics

#TycoonWorld #Inito #SeriesBFunding #HealthTech #AIinHealthcare #AtHomeDiagnostics #AIDiagnostics #DigitalHealth #FemTech #FertilityTech #BiotechInnovation #ProteinEngineering #SyntheticAntibodies #BertelsmannIndiaInvestments #FiresideVentures #StartupFunding #HealthcareInnovation #HormoneHealth #MedicalAI #IndiaStartups #DeepTech

https://tycoonworld.in/inito-raises-29m-series-b-to-advance-ai-powered-at-home-diagnostics/

🧩 Could structural AI finally decode the complex language of T-cell antigen recognition?

🔗 STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ProteinLanguageModels #Immunotherapy #ComputationalBiology #Bioinformatics #MachineLearning #Immunology #ProteinEngineering #TCR #HLA #DrugDiscovery #AI

STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004

✨ Is it time to rethink allosteric site prediction using internal protein nanoenvironments?

🔗 Protein allosteric site identification using machine learning and per amino acid residue reported internal protein nanoenvironment descriptors. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.036

📚 CSBJ: https://www.csbj.org/

#DrugDiscovery #ComputationalBiology #StructuralBiology #ProteinEngineering #Biophysics #Cheminformatics

Protein allosteric site identification using machine learning and per amino acid residue reported internal protein nanoenvironment descriptors. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.036

Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological University

Join us to work on AI for drug discovery!

See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/

#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=5646

💧 Is your MD simulation lying to you because of the water model you picked?

🔗 Impact of water models on the structure and dynamics of enzyme tunnels. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.051

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #Enzymology #StructuralBiology #ProteinEngineering #Biophysics #WaterModels #EnzymeTunnels #MolecularSimulation #ProteinDynamics

Impact of water models on the structure and dynamics of enzyme tunnels. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.051

🧬 Can molecular simulations transform the future of long-acting diabetes treatments?

🔗 In silico investigations of albumin-GLP-1 receptor agonist complexes for diabetes drug delivery applications. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.007

📚 CSBJ: https://www.csbj.org/

#MolecularDynamics #DiabetesResearch #Biotherapeutics #GLP1 #Albumin #DrugDelivery #Biomaterials #ComputationalBiology #ProteinEngineering

In silico investigations of albumin-GLP-1 receptor agonist complexes for diabetes drug delivery applications. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.007

💡 Can AI find the viral “on switch” that triggers infection?

🔗 Machine and deep learning to predict viral fusion peptides. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.011

📚 CSBJ: https://www.csbj.org/

#MachineLearning #Virology #AI #ProteinEngineering #Bioinformatics

Machine and deep learning to predict viral fusion peptides. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.011

🧬 Can AI build peptides that tell your cells to fight back against oxidative stress?

🔗 RoseTTAFold diffusion-guided short peptide design: a case study of binders against Keap1/Nrf2. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.032

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #PeptideTherapeutics #RoseTTAFold #ProteinEngineering #MolecularDynamics #AIinDrugDiscovery #AntioxidantResearch #DrugDesign #Bioinformatics #ComputationalBiology

RoseTTAFold diffusion-guided short peptide design: a case study of binders against Keap1/Nrf2. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.032

⚛️ Is the secret to circular rare earth recovery hidden in molecular motion?

🔗 Computationally derived structural insights into Rare Earth selectivity in lanmodulin and its variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.005

📚 CSBJ: https://www.csbj.org/

#RareEarths #Lanmodulin #ComputationalBiology #Sustainability #CircularEconomy #RareEarthElements #MolecularDynamics #ProteinEngineering #MolecularModeling #MolecularSimulation

Computationally derived structural insights into Rare Earth selectivity in lanmodulin and its variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.005

Implications: 100-color imaging, nanoscale drug sensing, real-time enzyme monitoring. What happens when quantum physics meets evolutionary biology?

📖 Full essay: https://helioxpodcast.substack.com/publish/post/76954473

Heliox: Where Evidence Meets Empathy 🇨🇦

#QuantumBiology #QuantumPhysics #Biotechnology #ScientificResearch #ProteinEngineering

Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological University

Join us to work on AI for drug discovery!

See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/

#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=4463

🧪 Can ionic liquids fine-tune enzyme activity and chirality without genetic modification?

🔗 Influence of ionic liquids on enzymatic asymmetric carboligations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.029

📚 CSBJ: https://www.csbj.org/

#Biocatalysis #EnzymeEngineering #GreenChemistry #IonicLiquids #EnzymeCatalysis #MolecularDynamics #StructuralBiology #ComputationalBiology #ProteinEngineering #AsymmetricSynthesis #Enzymology

Influence of ionic liquids on enzymatic asymmetric carboligations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.029

🧬 Can we trust AI to pick the next high-performance enzyme?

🔗 Structure-filtered search of enzyme variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.039

📚 CSBJ: https://www.csbj.org/

#ProteinEngineering #AlphaFold #EnzymeDiscovery #SyntheticBiology #StructuralBiology #ComputationalBiology

Structure-filtered search of enzyme variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.039

Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological University

Join us to work on AI for drug discovery!

See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/

#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=2489

IntegrateRNA launches revolutionary Aminoacyl-tRNA Synthesis Service enabling custom protein engineering with non-canonical amino acids, transforming research across pharma, biotech, and synthetic biology #Biotechnology #ProteinEngineering

🧩 The future of drug discovery may depend on how well we understand PROTAC-driven protein partnerships.

🔗 Mapping the energy landscape of PROTAC-mediated protein-protein interactions. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2023.02.049

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #PROTAC #DrugDiscovery #ComputationalBiology #ProteinEngineering #ProteinDegradation #Biopharma #MedicinalChemistry #TargetedTherapies #AIinBiotech #MolecularModeling