#ProteinEngineering

CSBJcsbj
2025-12-05

🧩 Could structural AI finally decode the complex language of T-cell antigen recognition?

πŸ”— STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.09

πŸ“š CSBJ: csbj.org/

STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004
CSBJcsbj
2025-11-20

✨ Is it time to rethink allosteric site prediction using internal protein nanoenvironments?

πŸ”— Protein allosteric site identification using machine learning and per amino acid residue reported internal protein nanoenvironment descriptors. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2024.10

πŸ“š CSBJ: csbj.org/

Protein allosteric site identification using machine learning and per amino acid residue reported internal protein nanoenvironment descriptors. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.036
CSBJcsbj
2025-11-16

πŸ’§ Is your MD simulation lying to you because of the water model you picked?

πŸ”— Impact of water models on the structure and dynamics of enzyme tunnels. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2024.10

πŸ“š CSBJ: csbj.org/

Impact of water models on the structure and dynamics of enzyme tunnels. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.051
CSBJcsbj
2025-11-16

🧬 Can molecular simulations transform the future of long-acting diabetes treatments?

πŸ”— In silico investigations of albumin-GLP-1 receptor agonist complexes for diabetes drug delivery applications. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.11

πŸ“š CSBJ: csbj.org/

In silico investigations of albumin-GLP-1 receptor agonist complexes for diabetes drug delivery applications. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.007
CSBJcsbj
2025-11-01

πŸ’‘ Can AI find the viral β€œon switch” that triggers infection?

πŸ”— Machine and deep learning to predict viral fusion peptides. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.02

πŸ“š CSBJ: csbj.org/

Machine and deep learning to predict viral fusion peptides. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.011
CSBJcsbj
2025-10-31

🧬 Can AI build peptides that tell your cells to fight back against oxidative stress?

πŸ”— RoseTTAFold diffusion-guided short peptide design: a case study of binders against Keap1/Nrf2. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.02

πŸ“š CSBJ: csbj.org/

RoseTTAFold diffusion-guided short peptide design: a case study of binders against Keap1/Nrf2. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.032
CSBJcsbj
2025-10-27

βš›οΈ Is the secret to circular rare earth recovery hidden in molecular motion?

πŸ”— Computationally derived structural insights into Rare Earth selectivity in lanmodulin and its variants. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.02

πŸ“š CSBJ: csbj.org/

Computationally derived structural insights into Rare Earth selectivity in lanmodulin and its variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.005
Zoomers of the Sunshine Coast πŸ‡¨πŸ‡¦SCZoomers@mstdn.ca
2025-10-25

Implications: 100-color imaging, nanoscale drug sensing, real-time enzyme monitoring. What happens when quantum physics meets evolutionary biology?

πŸ“– Full essay: helioxpodcast.substack.com/pub

Heliox: Where Evidence Meets Empathy πŸ‡¨πŸ‡¦

#QuantumBiology #QuantumPhysics #Biotechnology #ScientificResearch #ProteinEngineering

CSBJcsbj
2025-10-18

πŸ§ͺ Can ionic liquids fine-tune enzyme activity and chirality without genetic modification?

πŸ”— Influence of ionic liquids on enzymatic asymmetric carboligations. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.09

πŸ“š CSBJ: csbj.org/

Influence of ionic liquids on enzymatic asymmetric carboligations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.029
CSBJcsbj
2025-10-14

🧬 Can we trust AI to pick the next high-performance enzyme?

πŸ”— Structure-filtered search of enzyme variants. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.09

πŸ“š CSBJ: csbj.org/

Structure-filtered search of enzyme variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.039
Newsrampnewsramp
2025-08-31

IntegrateRNA launches revolutionary Aminoacyl-tRNA Synthesis Service enabling custom protein engineering with non-canonical amino acids, transforming research across pharma, biotech, and synthetic biology

CSBJcsbj
2025-08-30

🧩 The future of drug discovery may depend on how well we understand PROTAC-driven protein partnerships.

πŸ”— Mapping the energy landscape of PROTAC-mediated protein-protein interactions. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2023.02

πŸ“š CSBJ: csbj.org/

Mapping the energy landscape of PROTAC-mediated protein-protein interactions. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2023.02.049

Client Info

Server: https://mastodon.social
Version: 2025.07
Repository: https://github.com/cyevgeniy/lmst