I guess there was a study that claimed Metformin wasn’t helpful with covid in people who are not obese. This looks like a good rebuttal with some valid points about why the study wasn’t so good.
“Metformin Therapy for Patients With COVID-19 Without Obesity”
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2842942
This is crazy making. This JAMA article is about how this flu strain is particularly nasty, partly because they didn’t know this would be the predominant one until after vaccines were made & it mentions “respiratory hygiene, such as staying home when you’re sick”, but there’s no mention of prevention.
https://jamanetwork.com/journals/jama/fullarticle/2843197
This person, this pharmacist (?) in the comments, is the only one in this article to talk about how airborne viruses aren’t inevitable & it would be better to not act like they are.
Then the next comment is some clown talking about how it’s best to let our immune system battle it (rather than vaccines or antivirals I guess).
Anyway, the pharmacist’s comment had some links if you’re interested.
Nicola Boyd, PhD Comp. Chemist | Durham University
“The authors state the concerning but not unexpected behaviour of seasonal influenza viruses – that they evolve and mutate rapidly, causing unacceptable levels of illness every year, prompting a never ending arms race for vaccine developers. It is encouraging that the authors do acknowledge that the influenza vaccines are sub-optimal – ‘I wish we had better flu vaccines that, if you got it, you’re not going to get the flu….That’s not the case’. Beyond this however, in common with much of the medical and public health community, the overall outlook remains confined by a narrow and somewhat blinkered mindset.
The underlying fundamental judgement implied here is that respiratory infections are inevitable, and the only reasonable option is downstream mitigations via relatively poorly performing pharmaceutical interventions.
Outside the medical realm, aerosol engineers have a great deal of understanding about how airborne viral transmission occurs and how this can be curtailed. UVC/Far-UVC air and surface disinfection, HEPA/MERV filtration, and ventilation are technologies that can remove and destroy multiple pathogens simultaneously 'outside the human host'. The importance of this latter point cannot be overstated, as it means that pathogens have no mutational space to explore, thus creating an evolutionary dead end for replicating entities. These truly preventative solutions not only reduce the disease burden, but in doing so will also allow us to extract better value from vaccines and anti-virals by significantly slowing the evolutionary process of such troublesome diseases.
I believe that we will only make significant progress if the medical establishment breaks away from the ‘surrender narrative’ that airborne viral infections are inevitable, and starts to integrate medical interventions with engineering solutions for transmission control and potential elimination, in a truly preventative strategy.”
References:
https://www.science.org/doi/10.1126/science.abd9149
https://www.nature.com/articles/s41467-024-47777-5
https://www.nature.com/articles/s41598-024-57441-z
A New H3N2 Influenza Strain Is Raising Concerns About This Flu Season
https://jamanetwork.com/journals/jama/fullarticle/2843197/
#Medical #News
from #JAMA
December 19, 2025
#Flu season comes around every year, but a new strain is leading many #GlobalHealth experts to worry that this round may be particularly severe. The strain—a version of the #influenza A(#H3N2) #virus—first appeared in surveillance reports in June, 4 months after the 2025-2026 #InfluenzaVaccine formulation had already been determined, and has been associated with earlier waves of influenza outbreaks in #Canada, #Japan, and the #UK.
#DNA #Jama Οι κορυφαίες ιατρικές έρευνες του 2025, σύμφωνα με το περιοδικό JAMA https://www.zougla.gr/ygeia/erevnes/oi-koryfaies-iatrikes-erevnes-tou-2025-symfona-me-to-periodiko-jama/?utm_source=dlvr.it&utm_medium=mastodon
Precision Immunotherapy Improves Sepsis Outcomes
#Sepsis #Immunotherapy #RCT #JAMA #ClinicalTrials #PubMed #Pub2Post
Covid-19 mRNA Vaccination and 4-Year All-Cause Mortality
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2842305
#HackerNews #Covid19 #Vaccination #mRNA #Mortality #HealthResearch #JAMA
Trump admin axed 383 active clinical trials, dumping over 74K participants https://arstechni.ca/5B3Q #clinicaltrials #Health #grants #JAMA #NIH
Caffeinated coffee consumption or abstinence to reduce atrial fibrillation
https://jamanetwork.com/journals/jama/fullarticle/2841253
#HackerNews #CaffeinatedCoffee #AtrialFibrillation #HealthResearch #CoffeeAbstinence #JAMA
Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections: A Phase 2 Randomized Clinical Trial | Infectious Diseases | JAMA Internal Medicine | JAMA Network https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2838335
“Question Is regular application of azelastine nasal spray associated with reduced risk of SARS-CoV-2 infections?
Findings In this randomized placebo-controlled clinical trial that included 450 participants, the incidence of laboratory-confirmed SARS-CoV-2 infections was significantly lower with application of azelastine nasal spray compared with placebo treatment.
Meaning The use of azelastine nasal spray may help to reduce the risk of SARS-CoV-2 infections.”
#JAMA #azelastine #covid
Cognitive Disabilities on the Rise, Especially in Younger Adults
“Prevalence was consistently higher in individuals with chronic diseases, household incomes of less than $35,000 a year, and those living in the Midwest and US territories.”
Shocking, whatever could be causing the cognitive disabilities?? /s
https://jamanetwork.com/journals/jama/fullarticle/2840184
No fuck this.
AI, Health, and Health Care Today and Tomorrow
The JAMA Summit Report on Artificial Intelligence
https://jamanetwork.com/journals/jama/fullarticle/2840175
No. Please talk to your doctor about your objections to this. This is gross.
“The quality improvement study took place across 6 health care systems and included primary care practitioners, attending physicians, and academic faculty. The results suggest that implementing AI to handle administrative tasks may grant clinicians a greater capacity to focus on their patients and protect their professional well-being, the authors wrote.”
This is interesting. The author of the acetaminophen study clarifies some things.
Acetaminophen Use in Pregnancy—Study Author Explains the Data
These psychopaths are considering NOT disclosing AI use in patient care.
From the link-
“A recent JAMA Perspective, ‘Ethical Obligations to Inform Patients About Use of AI Tools,’ proposes a framework to guide health care organizations in making disclosure decisions. The authors argue that patient notification should be based on whether patients have meaningful agency to respond to the information as well as the degree of physical risk involved.”
Prostatitis is defined as infection, inflammation, or pain of the prostate gland and affects approximately 9.3% of men in their lifetime. #JAMA jamanetwork.com/journals/jam...
Now, a new study of nearly 34,000 veterans, finds this over-the-counter supplement is linked to a reduction in non-melanoma skin cancers among people who've already had skin cancer. The research was published in JAMA Dermatology.
The biggest reduction was seen among people who began taking the supplement after being diagnosed with their first skin cancer. Researchers found those who took 500 mg of nicotinamide, also known as niacinamide, twice daily, for at least one month, had a 54% reduced risk of developing another skin cancer, compared to patients who did not take the supplement. #jama #b3
They’re going to treat ADHD meds like opioids now, aren’t they?
“More Than Half of US Overdose Deaths Now Involve Stimulants”
https://jamanetwork.com/journals/jama/fullarticle/2839215
Wie sich das #Diabetesrisiko besser vorhersagen lässt: #JAMA-Studie zeigt: Kombination aus #Blutzucker, Alter, Geschlecht und Gewicht entscheidend. https://www.diabsite.de/aktuelles/nachrichten/2025/250914.html
@frauloop @vektorgarten @Crypty
Two-dose treatment for staph bloodstream infections
September 16, 2025 At a Glance Two doses of the antibiotic dalbavancin produced results similar to standard 4-…
#NewsBeep #News #Headlines #antibiotic #bacteremia #dalbavancin #Dalvance #JAMA #JournaloftheAmericanMedicalAssociation #Latvia #LV #NicolasA.Turner #staph #Staphylococcusaureus #ThomasHolland
https://www.newsbeep.com/126641/
These people will try absolutely anything except wearing a mask.
“A Novel Approach for Preventing Respiratory Virus Infections”
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2838339
