#Phage-induced #protection against lethal #bacterial #reinfection, https://etidiohnew.blogspot.com/2025/06/phage-induced-protection-against-lethal.html

@Vampykitten
Controversial episode. Weirdly, the show never tells us what #Neelix and #Tuvok thought of the decision, or what they remember (if anything) of #Tuvix.

Janeway is faced with a somewhat similar decision in the earlier #Phage, where the Vidiian who stole Neelix's lungs can't return the lungs because they have already been genetically modified, and it would kill the Vidiian. In this case she says rather forcefully that her ethics prevent her from killing someone.

Interesting show.🤔

That's a helluva ethical conundrum #Janeway was in after capturing the Vidians, and I can't believe she decided to release them with a warning. (At least she did it while yelling at them!)

I also can't believe she let disease ravaged terminally ill aliens wonder about the ship without containment. #StarTrek sometimes makes zero sense. 🤦‍♂️

#AllStarTrek #StarTrek #StarTrekVoyager #Phage

Damn, the Vidians had been dealing with the Phage for 2 millenia until they suddenly met the #ThinkTank, wow. 😬

#AllStarTrek #StarTrek #StarTrekVoyager #Phage

I don't think I've ever seen this episode before. 🤔🙂

#AllStarTrek #StarTrek #StarTrekVoyager #Phage

Between the medical scene in #Caretaker, and these Vidians, I forgot how gross early #StarTrekVoyager could be. 🤢

#AllStarTrek #StarTrek #Phage

A fan poster for tomorrow night's Star Trek: Voyager episode #Phage on H&I All Star Trek.
https://www.handitv.com/allstartrek

Artist: James Robert Rye

Source: https://www.trekbbs.com/threads/voyager-episode-posters.308580/

#StarTrek #StarTrekPoster #AllStarTrek #StarTrekVoyager #JamesRobertRye

A precursor procapsid is initially formed during #bacteriophage assembly, but how? The #cryoEM structure of the scaffolding protein complex & portal within #phage P22 procapsid reveals how this complex orchestrates the initiation of procapsid assembly @PLOSBiology https://plos.io/44B71iE

#UTISky meet team #phage Compelling summary slide from #ESCMIDGlobal #IDSky

RE: https://bsky.app/profile/did:plc:d5twxexrwk5fwdvyvlbvycgb/post/3lmkfnz4fi22g

PHORCE allows measurement of lytic #phage amplification rates in bacterial populations. This study uses PHORCE to reveal phenotypic diversity among #Ecoli & #Paeruginosa phages; phage- #antibiotic interactions are mainly determined by the drug @PLOSBiology https://plos.io/3G2myhf

How does the lysogenic-lytic cycle work in intestinal #bacteriophages? @dbikard &co show that hankyphage produces defective viral particles & identify RepCHP as master repressor of this #phage's lytic cycle #plosbiology https://plos.io/41Rr22S

#otd #startrek #voyager #Phage #janeway #chakotay #tuvok #kim #paris #belannatorres #kes #emh #neelix #dereth #motura #seska #Vidiians #startrek58 @trekcore

The Zorya Anti-Phage Defense System sounds like a hardcore sci-fi missile defense deployed by the Xanthan Conglomerate over their Ytterbium mines. It isn’t, but it kinda sounds like it is.

https://phys.org/news/2025-01-bacteria-anti-missile-defense-fend.html

#bacteria #phage #scifi #medicine #biology #antiviral

Nice work by Sanika Vaidya (and collegues)
done during our PhDs together at @maxplanckgesellschaft and @unibasel

Peptidoglycan triggers #biofilm formation across bacterial species.

https://www.nature.com/articles/s41564-024-01886-5

#openaccess #mpg #mpitm #phage #V_cholerae #bacteria #nature #microbiology #science #research

"We developed a method of #phage-assisted continuous evolution we call IntePACE..to systematically improve activity of PhiC31 & Bxb1 serine integrases..hyperactive mutants were generated..resulting in integration of a multi-gene cargo at rates as high as 80%..Hyperactive integrases inserted a 15.7 kb therapeutic #DNA cargo..This #technology could accelerate #gene delivery #therapeutics & our directed evolution strategy can easily be adapted to improve novel #integrases"

https://academic.oup.com/nar/article/52/14/e64/7702507?login=false

@helenczerski

How phages work:

Source: VIRUS, 2016
Dr Marilyn J Roossinck
Foreword by Carl Zimmer

101 INCREDIBLE MICROBES FROM CORONAVIRUS TO ZIKA

#books
#virus
#phage

Coinfecting #viruses obstruct each other's cell invasion https://phys.org/news/2024-08-coinfecting-viruses-obstruct-cell-invasion.html Paper: https://www.cell.com/current-biology/abstract/S0960-9822(24)00675-4

When there were more #phages attached to the surface of the cell, relatively fewer of them were able to enter... the first stage of infection, #phage entry, is an important step that was previously underappreciated... the coinfecting phages were impeding each other's entry by perturbing the #electrophysiology of the cell.

Passionate about phages? 🤩 Apply by July 31 to join Jens Hör’s research group as a doctoral researcher! In #HIRI’s Hör lab, you will study how bacteria defend themselves against #RNA #phage infection and decipher the molecular mechanisms of this defense. More at: https://www.helmholtz-hiri.de/en/jobs-talents/working-at-hiri/

Première : des chercheurs ont réussi à modifier le génome de bactéries dans l’intestin - Sciences et Avenir https://www.sciencesetavenir.fr/sante/premiere-mondiale-des-chercheurs-ont-reussi-a-modifier-le-genome-de-bacteries-directement-dans-l-intestin_179497?xtor=RSS-16 #biotechnologie #génome #génétique #intestins #bactéries #adn #microbiote #phage

i did a Summer internship studying homing introns in college. big advance!

"This work demonstrates how a homing endonuclease can be deployed in interference competition among viruses and provide a relative fitness advantage. Given the ubiquity of homing endonucleases, this selective advantage likely has widespread evolutionary implications in diverse plasmid and viral competition as well as virus-host interactions."

#homing #endonuclease #phage #bacteriophage #virus

https://www.science.org/doi/10.1126/science.adl1356