#myokines #skeletalmuscle #mood #exercise #metabolism #glucose #interleukin6 #fitness #wellnessmatters #holisticwellbeing #wellnessmama #wellnesscoaches #wellnessproducts #wellnessday #health #wellbeing https://mastodon.social/@biohackingpathway/115788882611776430
#skeletalMuscle
Just Published!
Sex-Related Neuromuscular Adaptations to Youth Obesity: Force, Muscle Mass, and Neural Issues
Referenced link: https://medicalxpress.com/news/2023-05-mutation-ribosomal-protein-heart-skeletal.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-05-mutation-ribosomal-protein-heart-skeletal.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1659539924486348801#m
RT by @physorg_com: Mutation in #ribosomalprotein in heart and #skeletalmuscle leads to impaired cardiac contractility in mice @NatureComms https://medicalxpress.com/news/2023-05-mutation-ribosomal-protein-heart-skeletal.html
"To examine whether #muscle contraction changes the distribution of #carnitine and its derivatives, unilateral in situ muscle contraction was performed; 60 min muscle contraction showed increased d3-carnitine and its derivative d3-acetylcarnitine in the muscle, indicating that carnitine uptake in cells is promptly converted to acetylcarnitine, consequently, buffering accumulated acetyl-CoA."
Postdoctoral Fellow in Muscle Biology @MCML_UF
Join us in the Molecular Cardiology and Myology Lab at #UF @MCML_UF to study #skeletalmuscle physiology and #spinal cord injury
#ScienceJobs #job
Gainesville #UnitedStatesUS ...
https://jobrxiv.org/job/university-of-florida-27778-postdoctoral-fellow-in-muscle-biology/?feed_id=42792
The "molecular athlete" is now out in the final form! Available #openaccess in Physiological Reviews (see link below).
Great collaboration with Regula Furrer of our very own lab @biozentrum @unibasel_en and John A. Hawley of the Australian Catholic University in Melbourne, Australia.
What to expect (a short thread):
1/8
https://doi.org/10.1152/physrev.00017.2022
#exercise #muscle #myomastodon #ScienceMastodon #athlete #endurancetraining #resistancetraining #skeletalmuscle
Postdoctoral Fellow @MCML_UF
Full-time #PostDocPosition available for training in #skeletalmuscle and #respiratorybiology @UF_HHP @MCML_UF
https://jobrxiv.org/job/university-of-florida-27778-postdoctoral-fellow/?feed_id=35977
#ScienceJobs #job
Gainesville #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/university-of-florida-27778-postdoctoral-fellow/?feed_id=35977
Just Published!
Impact of Cancer-Related Sarcopenia on Systemic Immune Status
ATF3+ lung capillary #EndothelialCell proliferates & promotes #AlveolarRegeneration post H1N1 injury #Flu
🫁ATF3 KO EC 14 dpi->
⏬Proliferation
⏫Apoptosis
Altered Angiogcrine🤠🧐 to⏬AT1+AT2 epithelial cells
Dr. Edward E. Morrisey lab bioRxiv 2022
https://www.biorxiv.org/content/10.1101/2022.10.14.512212v1.full
Reminiscent of the really cool work from Dr. Katrien De Bock @cell_metabolism 2021
#SkeletalMuscle ATF3/4+ Capillary #EndothelialCell, preferably surrounding oxidative myofibers, as a major cellular origin of Exercise-induced #Angiogenesis😎
https://www.sciencedirect.com/science/article/pii/S1550413121003314
#Autophagy in🐭#LimbIschemia 1/2
AMPK or Sestrin as potential autophagic regulators
Dr. Mattia Scalabrin & Scott Bowen lab AJP CellPhys 2022
https://journals.physiology.org/doi/abs/10.1152/ajpcell.00174.2022
Which tissue does autophagy occur in (likely #SkeletalMuscle based on Western blot)? And its functional impacts?
#Autophagy in🐭#LimbIschemia 2/2
Evidence on autophagy induced by ischemia/#Hypoxia in #EndothelialCell, and its stimulatory effects on #Angiogenesis
Dr. Joo-Won Jeong lab Cell Death Dis 2020
https://www.nature.com/articles/s41419-020-02849-4
They found that 62% of the #tissue was #skeletalmuscle tissue and that it contained PAX7+ #myogenic @stem / #progenitor cells, MYOD+ activated/committed #myoblast s, and MYOG+ #myocyte s. They also found that 31% of PAX7+/Ki67− and 29% of MYOD−/PAX7+ non-dividing quiescent SCs were present in the mature #hSkMO s. This indicates that the #hSkMO s were able to effectively recreate @embryo nic #myogenesis and have regenerative potential.
This indicates that the in vitro #hSkMO @culturesystem is able to recapitulate the features of embryonic skeletal @muscle development.
The different types of #SkeletalMuscle stem/progenitor cells that are involved in myogenesis, the process of muscle formation.
The researchers used qRT-PCR analysis and #immunohistochemistry to identify and characterize the different types of cells.
Scientists have been trying to create models to study how #Skeletalmuscle develops and regenerates. Recently, they have been using human pluripotent #StemCell to create 3D models of skeletal muscle tissue. However, these models have not been able to recreate the full process of muscle regeneration. In this research paper, the authors introduce a new method of using human pluripotent stem cells to create 3D models of skeletal muscle tissue that can retain the ability to repair itself.
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