#synbio

Boas Puckerboas_pucker
2026-01-31

🧬 Attention iGEM teams!

Are you starting a new project and thinking about biosafety systems? This is a great resource to explore different containment strategies:

📘 Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications

➡️ doi.org/10.1186/s13036-018-010

From engineered auxotrophy to xeno-DNA containment, it is full of ideas that could help shape your design and safety planning.

Comprehensive combination of biosafety mechanisms in E. coli. Details: https://doi.org/10.1186/s13036-018-0105-8
2026-01-28

Synthetic Biology for Light-Activated Smart Materials

Design and characterise light-responsive proteins and demonstrate light-controlled behaviour of cell-free biology in materials.

#SynBio, #StructuralBiology, #ProteinEngineering, and #biomaterials.

#PhD Studentships are fully funded for 4yrs, with minimum of 3 months at the industry partner. Funding for home (UK) students = tax-free stipend (indicative in year 1 in 2026-27 (£21,383), research costs and tuition fees.
findaphd.com/phds/project/synt

Paul HouleUP8
2025-12-10

🧬 Largest RNA language model to date offers new way to predict behavior and boost drug discovery

phys.org/news/2025-11-largest-

2025-12-09

I have a postdoctoral research post available in my lab. Please share, especially suitable for #EngBio #SynBio people, or Metabolic Engineers.

Its a cell-free metabolic engineering project, and part of a bigger, multi-year effot: ncl.ac.uk/press/articles/lates

Job Listing: jobs.ncl.ac.uk/job/Newcastle-R

2025-12-01

#Methode: Effizientes Klonieren? Eine Frage der Koordination! Das Open-Source-Tool #CloneCoordinate, entwickelt vom Team um Ben Thuronyi (USA), ist eine Open-Source-Softweare für kollaborative DNA-Konstruktion. Mehr im Laborjournalartikel von Andrea Pitzschke: laborjournal.de/editorials/338
#SynBio #LabLife

@thuronyi

ALT: Links befindet sich eine Grafik, die den Ablauf eines koordinierten Klonierungsvorgangs darstellt. Rechts daneben steht die Überschrift des im Post angekündigten Artikels „Koordiniertes Klonieren”. Es folgt dessen Vorspann mit dem Text: „Bei Klonierungen wursteln Forschende häufig alleine vor sich hin. Ein Software-Tool hilft dabei, die tägliche Kloniererei effektiver und produktiver zu gestalten.“
2025-11-30

SYNTHETIC + MOLECULAR BIOLOGY on MICROPLASTICS - POSTDOCTORAL FELLOW
University of Toronto

Turn your #PostDoc into a Global Impact. 🌍 Join @UofT/#RNAlab to evolve plastic-degrading enzymes #SynBio. 🧬🔬

See the full job description on jobRxiv: jobrxiv.org/job/university-of-

#b...
jobrxiv.org/job/university-of-

2025-11-27

Learn more about Twist and #SynBio at Rhymes with Haystack, link in bio.

2025-10-26

🎃 Have you picked your Halloween costume? 🎃 And more importantly, have you submitted your papers to our upcoming special issue on Advances in Plant Natural Products: #Biosynthesis, #Bioengineering, and Applications.

jipb.net/EN/news/news863.shtml

#PlantScience #medicine #food #beauty #agriculture #botany #SynBio

Screenshot of the JIPB webpage detailing a call for papers for the upcoming special issue, Advances in Plant Natural Products: Biosynthesis, Bioengineering, and Applications.
2025-10-14

This #FreeAccess Brief Communication describes an optimized prime editing system in a model #medicinal #plant that allows precise editing of key #genes and generates germplasm with elevated amounts of #bioactive tanshinone, advancing #SynBio applications in medicinal plants.

💊 doi.org/10.1111/jipb.70006

#PlantSci #botany

Diagram describing an optimized prime editing system developed by Yao et al. in the model medicinal plant Danshen (Salvia miltiorrhiza) that enables base transversions, complex insertions and base substitutions.
2025-10-12

SYNTHETIC + MOLECULAR BIOLOGY on MICROPLASTICS - POSTDOCTORAL FELLOW
University of Toronto

Turn your #PostDoc into a Global Impact. 🌍 Join @UofT/#RNAlab to evolve plastic-degrading enzymes #SynBio. 🧬🔬

See the full job description on jobRxiv: jobrxiv.org/job/university-of-

#e...
jobrxiv.org/job/university-of-

2025-10-10

SYNTHETIC + MOLECULAR BIOLOGY on MICROPLASTICS - POSTDOCTORAL FELLOW
University of Toronto

Turn your #PostDoc into a Global Impact. 🌍 Join @UofT/#RNAlab to evolve plastic-degrading enzymes #SynBio. 🧬🔬

See the full job description on jobRxiv: jobrxiv.org/job/university-of-

#e...
jobrxiv.org/job/university-of-

2025-10-02

We are excited to welcome our next iGEM Bonn team for the 2025/2026 cycle! 🌍✨

The students are already gearing up for a year of innovation in synthetic biology, and we are proud to support their journey.

👉 Meet the new team here: igem-bonn.org/team-2026/

Let’s cheer them on as they begin their iGEM adventure!

#iGEM2026 #iGEM #SynBio #Teamwork #Innovation
@boas_pucker @samnm

Yasoo 🧬 🌱yasoo@genomic.social
2025-09-29

Preparing a Journal club about rubisco directed evolution for tomorrow

nature.com/articles/s41477-025

#photosynthesis #synbio #ecoli

2025-09-17

This #review examines how advances in #plant #genomics and #SynBio have accelerated research on plant prenyltransferases in natural product synthesis, positioning them as a focal point for prenylated natural product-based #drug development.
doi.org/10.1111/jipb.70004
@wileyplantsci
#PlantScience #medicine #botany

Diagram summarizing the classification, function, catalytic mechanisms, and enzyme engineering strategies of plant PTs, and their application in the heterologous production of PNPs.
2025-08-26

Investigating morphogen and patterning dynamics with optogenetic control of morphogen production

"🎵 Efficient, logical, effective, and practical 🎶". Also: beautiful.

Congratulations to Dirk Benzinger & James Briscoe.

#PaperThemeTune is "ChemiOptoGenetic Engineering" by Orchestral Manoeuvres in the Dark #ShowingMyAge

sciencedirect.com/science/arti

#DevBio #SynBio

2025-08-09

New issue! Featuring reviews on #SynBio #biofortification and transcription factor engineering to improve #yield, plus research articles spanning #PlantScience. Free to read for a limited time! 🔓 onlinelibrary.wiley.com/toc/17

August cover of JIPB, featuring an artist's image of figures coming out of a Trojan horse, while other figures in the distance prepare to attack. The image demonstrates that the rice phytocytokine IMMUNE RESPONSE PEPTIDE 1 (IRP1) and its derived peptides resemble hidden soldiers, hiding in ambush inside pest frass (the “Trojan Horse”) during pest feeding, and finally activating rice plant defenses.
Thế Giới Trong Tầm Tayvietworldnow
2025-08-08

Thử thách SynBio lần thứ 4 tại Thâm Quyến đã quy tụ hơn 265 đội và gần 1.900 tài năng trẻ từ khắp nơi trên thế giới. Họ đã tạo ra những giải pháp bền vững cho các vấn đề thực tiễn. Đây là cơ hội để sáng tạo và đổi mới cho thế hệ tương lai! ift.tt/15iGOZY

2025-06-13

Synthetic biology-based #biofortification of crop plants may be the key to addressing hidden #hunger caused by chronic #micronutrient deficiencies, which affect billions of people. Learn more in this #OpenAccess mini-review!
doi.org/10.1111/jipb.13934
#PlantScience #SynBio 🔓 #botany

Plant synthetic biology-based strategies for biofortification: (A) Overview of the vitamin B1 de novo biosynthesis pathway in plants. (B) The strategy of overexpression of endogenous biosynthetic genes. (C) The strategy of introduction of heterologous biosynthetic pathways. (D) The strategy of expression of nutrient-specific transporters. (E) The “suicide” catalytic mechanism of THI1 in higher plants and other eukaryotes, in which its cysteine residue is irreversibly consumed, resulting in enzyme inactivation after a single turnover. (F) The strategy of optimization of transcriptional regulation via transcription factor or promoter engineering. (G) The strategy of protein (directed) evolution.
James Hawley, PhDjrhawley@scholar.social
2025-06-11

An old friend of mine has a blog about #synBio, #genomics, and #biology. Here's the first post in a series on genome sequencing technology:

editlife.substack.com/p/part-1

2025-06-05

Site-specific DNA insertion into the human genome with engineered recombinases www.biorxiv.org/content/10.1... in other words... genome engineering to precisely insert large multi-kilobase sequences into specific sites without introducing double-strand breaks #synbio

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