New publication out 🆕 📤

"No evidence of transposable element bursts in the Galápagos Scalesia adaptive radiation despite hybridization, diversification and ecological niche shifts"

https://mobilednajournal.biomedcentral.com/articles/10.1186/s13100-025-00362-z

🔍 Despite rapid speciation, niche shifts, & hybridization, we found no significant TE accumulation differences across species or hybrids.
🌵 Even in arid-adapted lineages—where genome downsizing may be expected—TEs didn’t decline.
#TransposableElements #Speciation #AdaptiveRadiation #Genomics

Harnessing eukaryotic retroelement proteins for transgene insertion into human safe-harbor loci.
#GenomeEditing #GeneTherapy #TransposableElements
https://www.nature.com/articles/s41587-024-02137-y

Long-read detection of transposable element mobilization in the soma of hypomethylated Arabidopsis thaliana individuals.
#TransposableElements #SomaticTransposition #LongReads #Arabidopsis #PlantScience #Preprint
https://www.biorxiv.org/content/10.1101/2025.02.07.637047v1

#TransposableElements A Homage to Barbara McClintock and Hopi Zea mays, artwork series by Megan Singleton in #KernelsOfCulture #MaizeAroundTheWorld
This artwork commission is sponsored by Nancy Ridenour.
megansingleton.com
Pix: Hopi Purple and Hopi Turquoise photograph series and art book, photos by Virginia Harold

High short tandem repeat mutation recurrence in heat-stressed Arabidopsis thaliana lines.
#TransposableElements #Arabidopsis #HeatStress #ShortTandemRepeats #Preprint
https://www.biorxiv.org/content/10.1101/2025.01.24.634728v1

How tiny algae shaped the #evolution of giant clams https://phys.org/news/2025-01-tiny-algae-evolution-giant-clams.html https://www.nature.com/articles/s42003-024-07423-8

"T. maxima have evolved more genes for sensors to distinguish friendly #algae from harmful #bacteria, #viruses... it has tuned down some of its immune genes in a way that likely helps the #animals tolerate #microbes... As a result of the weakened #ImmuneSystem, its genome contains a large number of #TransposableElements left behind by viruses. These aspects highlight the tradeoffs of #symbiosis"

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development.
#TransposableElements #Retrotransposons #LINE-1 #InducedPluripotentStemCells #BrainOrganoids #Preprint
https://www.biorxiv.org/content/10.1101/2025.01.17.633315v1

Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing

#TransposableElements #Retrotransposons #Silencing #HuSH #LINE-1

https://www.nature.com/articles/s41467-024-53761-w

Transposable elements are prevalent vectors of transgenerational epigenetic inheritance in nature.
#TransposableElements #TEs #Arabidopsis #Epigenetics #Preprint
https://www.biorxiv.org/content/10.1101/2024.09.20.614076v1.full.pdf

Where do new genes come from? @HassanZaman91 @barricklab &co show that within the timescale of the #LTEE experiment, the co-option of #promoters, mainly from #TransposableElements, serves as the major source of raw material for #DeNovoGenes #PLOSBiology https://plos.io/4a8p6DT

My paper just got accepted just before the end-of-the-year celebrations 🥳 Although modest, the story remains cool and promising for future investigations in the coming years!
I focused on how transposable elements behave while mouse fetal gonads differentiate as testes or ovaries.
https://www.frontiersin.org/articles/10.3389/fcell.2023.1327410
#TEs #TransposableElements #developmental_biology #SexDet #biology #bioinformatics #RStats

My latest preprint exploring transposable element (TE) activity in the genomes of sparrows.

https://biorxiv.org/cgi/content/short/2023.10.26.564301v1

We found remarkably high levels of repeat content in the newly generated genomes of
Bell's, Song, and Savannah Sparrow. 31% of the Bell's sparrow genome is spanned by repetitive elements.
This is ~3x as much as previously reported in most songbirds.

Thanks to all my co-authors for their contributions to this project!

#Genomics
#TransposableElements
#ornithology
#sparrows

I can finally communicate about it! Here is my last preprint: https://www.biorxiv.org/content/10.1101/2023.10.23.563600v1
It is part of a collaborative project between my official lab from Tel-Aviv and my host lab in Montpellier. #SexDet #TransposableElements #stem #bioinformatics

.@AnnaOsnato &co explore a #PLOSBiology study which reveals a previously undefined group of cells in the early human #embryo that diverges from the main lineages & undergoes apoptosis through the activity of young #TransposableElements https://plos.io/3CHIA45

Many thanks to our incredible instructors (@clementgoubert and Valentina Peona) and this engaged group of attendees who made the Bioinformatic analysis of Transposable Elements course an absolute blast! 🌟👏
#Bioinformatics #TransposableElements #Genomics

🎉We're thrilled to be underway with our "Bioinformatic Analysis of Transposable Elements" course with two 💫exceptional and emerging talents @clementgoubert and @valepeona in the field of Transposable Elements science.

#Genomics #Bioinformatics #TransposableElements

Referenced link: https://phys.org/news/2023-05-prevalence-transposable-elements-clues-worldwide.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-prevalence-transposable-elements-clues-worldwide.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1653078311235469321#m

Prevalence of #transposableelements may provide clues to worldwide #mammal biodiversity @stonybrooku @sciencemagazine https://www.science.org/doi/10.1126/science.abn1430 https://phys.org/news/2023-05-prevalence-transposable-elements-clues-worldwide.html

🥁There are still a few seats available for some of our courses in May and June!
#Python #Rstats #singlecell #RNAseq #transposableElements #Metagenomics #GLMs #rspatial #Genomics #DataScience

Hi the fediverse!

Our lastest paper on the theoretical dynamics of transposable elements is out (in Theor Pop Biol: https://www.sciencedirect.com/science/article/pii/S0040580923000096 , in @biorxiv_evobio : https://www.biorxiv.org/content/10.1101/2022.07.05.498868v2). We derived population genetics models of TE amplification when regulated by piRNAs, accoding to the "trap model". -> Thread

#PopulationGenetics #TransposableElements #TheorPopBiol #piRNA #EvolutionaryBiology #EvoBio #Publication #Genomics

🥁Registration is now open for the course "Bioinformatic analysis of Transposable Elements" with Valentina Peona & @clementgoubert in June

🗓️ (online) June, 12-15

🔗https://physalia-courses.org/courses-workshops/course24/

💡 Attendees will learn how to conduct computational analyses of TEs, interpret the results in the light of TE biology, and improve TE annotations through manual curation

#TransposableElements #Genomics #Bioinformatics