Identification of FtsZ Interdomain Cleft Effectors Based on Pharmacophore Search and Molecular Docking - #FtsZ #IDC #effectors #ligandproteininteraction #pharmacophoresearch #moleculardocking - https://link.springer.com/article/10.3103/S0095452724050050

Membrane trafficking pathways play a prominent role in immunity of plants against diseases. #Effectors of #plant #pathogens have evolved to interfere with aspects of membrane transport systems and reprogram host plant vesicle traffic to overcome plant #resistance. Review by Enoch Lok Him Yuen and others - https://doi.org/10.1146/annurev-phyto-021622-123232

Very happy to share our preprint on fishing for #plant targets of ADP-ribosylating bacterial type III #effectors - great team effort, 🙏 thanks to everyone involved! (finally incl. some halfway decent MS2 spectra of the modification, 9 years later...😉) #slowscience #plantscience #ADPribosylation #plantimmunity https://biologists.social/@biorxivpreprint/111132762774432947

This #review summarises how pathogenic #effectors can mimic or target the highly conserved #ubiquitin–#proteasome system to disrupt cellular processes in their #plant hosts.

https://doi.org/10.1093/jxb/erad191

#ubiquitination #immunity #PAMP #effector

#Effectors play a central role in determining the outcome of #plant−#pathogen interactions and can provide fundamental knowledge of microbial pathogenesis and disease resistance. Review of plant pathogen effectors and the recently developed analytic tools and technologies for identifying them - article in Phytopathology (2023, vol. 113, issue 4, pp. 637-650) by Amelia H. Lovelace and others like @michhulin - https://doi.org/10.1094/PHYTO-09-22-0337-KD

#High-Throughput Discovery and Characterization of #Viral Transcriptional #Effectors in Human Cells | bioRxiv

https://www.biorxiv.org/content/10.1101/2022.12.16.520835v1

#synbio

#introduction
I am a #PhD student, and I would love to be in the loop about the following topics:
#fungicide #resistance #adaptation #GWAS #PopGen #Epigenetics #TE #genomics #EvolutionaryBiology #machinelearning #Epistasis #Phenomics #phenotyping #high #throughput #screening #genome #geneticnetworks #effectors #plantpathogen #gene #smallRNA #RNA #R #python #Bash #Linux #conda #GitHub and more!!