#pathogens

2025-10-06

#Plant NLRs help combat #pathogens. In the latest #JIPB commentary, Wang et al. discuss expanding functionalities of #immune receptors through simultaneous transfer of sensor and helper NLRs.
🔓 ➡️ doi.org/10.1111/jipb.70020

Wiley Plant Science
#PlantScience #agriculture #openaccess

This panel of three diagrams illustrates how cross-family deployment of sensor and helper NLRs confers effector-triggered immunity in non-asterid crops.
2025-10-01

RAND report:

When Should We Worry About AI Being Used to Design a Pathogen?

Key takeaways:

In 2025 and the near term, AI is and will likely continue to be an assistive tool rather than an independent driver of biological design.

No fundamental biological limits exist that would prevent AI from eventually having the capability to design pathogens.

As AI models become more capable, the risk landscape is shifting and is expected to expand over the longer term (i.e., after 2027), although experts were very uncertain how rapidly capabilities would evolve.

rand.org/pubs/research_briefs/

#ai #airesearch #rand #bioengineering #bioweapons #pathogens #artificialintelligence

2025-09-22

Did prehistoric sheep carry plague? 🐑🦠 A 3rd-millennium BCE Yersinia pestis genome from domesticated sheep links livestock to human infections in prehistory. #MetagenomicsMonday #SPAAM #aDNA #plague #pathogens #yersiniapestis #sheep #zoonosis #infection #ancientpathogens
doi.org/10.1016/j.cell.2025.07

2025-09-21

While humans have long used salicylic acid to relieve pain and inflammation, #plants produce it to defend against #pathogens. But how? Yan Li and Jie Luo explore its #biosynthesis from phenylalanine in a new #JIPB commentary!

doi.org/10.1111/jipb.70016

@wileyplantsci
#PlantScience #botany #FreeAccess

Schematic representation of the complete pathways for salicylic acid biosynthesis in plants.
Angstrom Mineralsangstromman
2025-09-09

Adding these to your is a measure against , as it helps fight to invade when you are already infected. And it assists with good bacteria in the and in the body.

GET SILVER HERE--->>> angstrom-minerals.com/collect.
GET APPLE CIDER VINAGER GUMMIES HERE--->>> angstrom-minerals.com/?dt_id=2

2025-09-01

As climate change warms ocean waters, Vibrio bacteria diseases are spreading northward along many coastlines #pathogens

scientificamerican.com/article

2025-08-30

Ever since they stopped monitoring multiple different #Foodborne #Pathogens a few months ago, I have gotten regularly sick definitely it being food poisoning basically every other week. Refrigerator is totally fine. The items that I purchase are packaged and handled properly. There isn’t a single specific food item that seems to stand out in a pattern. It seems to be multiple things. Some milk was definitely bad in unopened cartons, but that’s the only thing that had some telltale signs.

Don Curren 🇨🇦🇺🇦dbcurren.bsky.social@bsky.brid.gy
2025-08-27

#covid-19 may somehow impair the immune system’s “memory” of past infections, potentially making even healthy people more vulnerable to future #pathogens.” www.bmj.com/content/390/...

Why scientists are rethinking ...

2025-08-26

#Drumpf era #CDC has stopped monitoring for several factors it once tracked for foodborne illness outbreaks. As of July 1, a critical surveillance program is ordered to only monitori for two pathogens instead of the previous eight.

Currently only two #pathogens: #salmonella and #Shiga toxin-producing E. coli are being tracked federally, now ignored are #campylobacter, #cyclospora, #listeria, #shigella, #vibrio and #Yersinia.

nbcnews.com/health/health-news

2025-08-22

Why are there so few #pathogens, and what determines their emergence? This #PLOSBiology Perspective argues that #ecological and #evolutionary forces (host availability, geographic exposure and microbial innovation) will shape future human diseases.
plos.io/4mUst87

False color scanning electron microscopy image of E. coli bacteria. Image by Gerd Altmann from Pixabay
Benjamin Carr, Ph.D. 👨🏻‍💻🧬BenjaminHCCarr@hachyderm.io
2025-08-07

#Animal #diseases leapt to #humans when we started keeping #livestock
When #huntergatherers began living close to animals, the #pathogens that cause the #plague and #leprosy got closer too.
The #genomic study identified 5,486 #DNA sequences from #bacteria, #viruses and #parasites in blood remnants from bones and teeth spanning 37,000 years. #Zoonotic pathogens were detected only in remains 6,500 years old or younger.
nature.com/articles/d41586-025

2025-08-06

How #RFKJr #mRNA crackdown affects #vaccine making and future #pandemics. The #Trump administration is terminating #biodefense #research funding for mRNA projects, raising concerns about the nation’s ability to fight future #pandemics. #publichealth #medicine #healthcare #science #pathogens #flu #birdflu #HHS #taxpayers #RNA #biology #variants washingtonpost.com/health/2025

Benjamin Carr, Ph.D. 👨🏻‍💻🧬BenjaminHCCarr@hachyderm.io
2025-07-27

Live-animal markets across #SoutheastAsia continue operating as natural laboratories for deadly #pathogens despite warnings from #publichealth experts about their role in #disease transmission, according to research published in Nature.

Inside the thriving wild-animal markets that could start the next #pandemic
Live-animal markets are a natural laboratory for viruses to evolve and spark deadly outbreaks, yet scientists lack support to study the risks they pose.
nature.com/articles/d41586-025

2025-07-18

Transcription factor bHLH25 is a #crop superhero!
🛡️Oxidized, it boosts #lignin production to strengthen #plant #cell walls against #pathogens.
⚔️Non-oxidized, it activates #phytoalexins to inhibit pathogen growth.
🔓⬇️
doi.org/10.1111/jipb.13878
@wileyplantsci
#PlantSci #JIPB #botany

This diagram represents a model for basic helix-loop-helix 25 (bHLH25) sensing H2O2 and conferring disease resistance, illustrating the dual roles of TF bHLH25: Oxidized, it boosts lignin production to strengthen cell walls against pathogens; non-oxidized, it activates phytoalexins to inhibit pathogen growth.
2025-07-11

… and #diets rich in animal products, like #milk & #meat, could facilitat the spreading of such #pathogens from animals: doi.org/10.1038/d415... #plantbased #health

Animal diseases leapt to human...

2025-07-09

Ancient DNA reveals farming led to more human diseases

"Humans' close cohabitation with domesticated animals—and large-scale migrations of pastoralists from the Pontic Steppe—played a decisive role in the spread of these diseases...We've long suspected that the transition to farming and animal husbandry opened the door to a new era of disease—now DNA shows us that it happened at least 6,500 years ago. These infections didn't just cause illness—they may have contributed to population collapse, migration, and genetic adaptation."
>>
phys.org/news/2025-07-large-sc

"Today, zoonoses account for more than 60% of newly emerging infectious diseases."
Martin Sikora, The spatiotemporal distribution of human pathogens in ancient Eurasia, Nature (2025).
nature.com/articles/s41586-025
#pastoralism #farming #diseases #zoonosis #pathogens #livestock #cattle #domestication #civilisation #animal #husbandry #SettlerSociety #meat #pandemics #IndigenousPeoples

Angstrom Mineralsangstromman
2025-06-11

Zinc plays a central role in the , & people experience increased to a variety of . It is clear that zinc affects multiple aspects of the system, from the barrier of the to within . Zinc is crucial for normal & of cells mediating nonspecific such as and .
angstrom-minerals.com/?dt_id=2

2025-05-28

#Pathogens like M. oryzae and the rice stripe #virus severely impact #crop yields, but #RNAi-based #rice #disease management may turn the tide in this battle. Here, Chen et al. explore the potential of sprayable sRNA and dsRNA molecules.
doi.org/10.1111/jipb.13896
@wileyplantsci
#PlantSci #CropSci #Phytopathology #JIPB

In situ rice crop plant images, comparing mock, dsRNA(GFP), and dsRNA(RSV3) varieties at seedling and ripening stages. An RNA interference system using sprayable small RNA/double-stranded RNA with layered double hydroxides was developed to target Magnaporthe oryzae and rice stripe virus. This system enhanced RNA stability, suppressed fungal germination, and reduced viral replication, decreasing disease incidence, thus offering a scalable, eco-friendly solution for rice disease management.

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