Lmst

“Specifically, he was worried that an #A.I. would engineer a lethal #pathogen — some sort of #super-coronavirus — to eliminate #humanity. ‘I don’t think there’s anything close in terms of the scale of #danger,’ he said.” www.nytimes.com/2025/10/10/o... #AI

Opinion | The A.I. Prompt That...

Colletotrichum gloeosporioides is a major threat to #mango #crops. Here, Xiang et al. report that Histone deacetylase MiHDA3 enhances #fruit resistance to this devastating #pathogen by deacetylating MiCAT1.

🥭https://onlinelibrary.wiley.com/doi/10.1111/jipb.70023

Wiley Plant Science
#PlantSci #CropScience #botany

Diagram illustrating that in mango, the histone deacetylase MiHDA3 interacts with and deacetylates the catalase MiCAT1 at lysine residues K227 and K233; this deacetylation reduces MiCAT1 stability and enzymatic activity, resulting in increased H2O2 accumulation and enhanced resistance to anthracnose caused by Colletotrichum gloeosporioides in mango fruit.

One of the coolest things about #masks is that it doesn’t matter what variant or #pathogen or #allergen etc

it just filters you just have to wear it

https://bsky.app/profile/funnygodmother.bsky.social/post/3lx3pghnnek2x

#Politics #Democrats #Republicans #Liberals #Conservatives #Vote #Election #DemocraticParty #DNC #RepublicanParty #RNC #GOP #DonaldTrump #Trump #JDVance #Vance #JoeBiden #Biden #KamalaHarris #TimWalz #Democracy #US #USA #ElonMusk #Musk #Fascism #Fascist #BernieSanders #AOC #FraudSquad #Progressive #COVID #COVID19

Pipeline release! nf-core/taxprofiler v1.2.4 - v1.2.4 - Bouncy Basenji Patch!

Please see the changelog: https://github.com/nf-core/taxprofiler/releases/tag/1.2.4

#classification #illumina #longreads #metagenomics #microbiome #nanopore #pathogen #profiling #shotgun #taxonomicclassification #taxonomicprofiling #nfcore #openscience #nextflow #bioinformatics

🛡️Understanding #plant-#pathogen interactions helps protect crucial #food #crops.
This #MAPK signaling cascade contributes to #wheat stripe rust resistance, providing insights into crop immunity and #fungal #pathogenicity.
https://doi.org/10.1111/jipb.13888
@wileyplantsci
#PlantSci #JIPB #botany

Diagram of a wheat plant cell cross-section. On the left side of the cell, the TaMAKK2-TaMAPK6 kinase cascade phosphorylates the core immune regulator TaSGT1 and promotes its nuclear entry, contributing to resistance to stripe rust; on the right, an effector from the fungal pathogen that causes stripe rust targets and blocks this process.

#Fungal genus Phaeolus is a significant #conifer #pathogen. Cui et al.'s analysis of its #phylogeny, #divergence times, and #biogeography sets the foundation for future pathogen control and #ecological #conservation.
https://doi.org/10.1111/jse.13187
@WileyEcolEvol
#JSE #forestry #trees #botany

Panel of morphological images and phylogenetic datasets from a study that establishes a robust phylogenetic tree, molecular clock dating, and biogeography of the phytopathogenic fungal genus Phaeolus, established based on internal transcribed spacers (ITS) and nuclear large ribosomal subunit (nLSU) sequences.

Beach day? NOT! Eeeeewwww!

#Pathogen risk found at 78% of #Maine coastal #beaches tested in 2024, report finds

July 8, 2025

"The report noted Maine beaches with persistent pollution problems last year included #GoodiesBeach in #RockportME, #GoochsBeach in #KennebunkME, #CapeNeddick Beach, #LaiteBeach in #CamdenME, Little Beach in #OgunquitME, #FerryBeach in #ScarboroughME, #WillardBeach in #SouthPortlandME, #MothersBeach in Kennebunk, and #GooseRocksBeach in #KennebunkportME ."

Source:
https://www.msn.com/en-us/health/other/pathogen-risk-found-at-78-of-maine-coastal-beaches-tested-in-2024-report-finds/ar-AA1Icy9m?ocid=winp2fptaskbar&cvid=d56d1d887b4b43bb9d10ee87215742d4&ei=8

#WaterIsLife #MaineBeaches #SewagePollution #OceansAreLife

#Huanglongbing, a.k.a. #citrus greening disease, is a devastating, incurable #bacterial disease of citrus #trees, but new #AI-driven research by Liu et al. suggests paradigms for #sustainable #pathogen control.
Read more here: https://doi.org/10.1111/jipb.13949
@wileyplantsci
#PlantSci #botany

Diagram highlighting the mechanistic basis of MYC2 stabilization in conferring citrus Huanglongbing resistance, and demonstrating how the CLas effector SDE5 subverts host immunity by enhancing PUB21–MYC2 interactions.

【💡High Cited 】
#EcologicalPrinciples to guide the development of #CropVarietyMixtures🧑‍🌾

Niche differences underlying the different environmental responses can indicate functional complementarity and promote #MixtureYield and #YieldStability.

#Agroecology | #PlantBreeding | #CommunityEcology | #Pathogen/diseaseControl

https://doi.org/10.1093/jpe/rtad017

How One Gene Helped Plague Persistently Cause Pandemics

Bubonic plague has caused the deadliest pandemic in history. The bacterium that causes bubonic plague, known as Yersinia pestis can cause severe illness and death. Now reporting in Science, researchers have shown how one gene in the Yersinia pestis genome has enabled its survival over hundreds of years, with tweaks to virulence and deadliness.

#plague #genetics #science #research #biology #pathogen

https://www.labroots.com/trending/genetics-and-genomics/29133/gene-helped-plague-persistently-cause-pandemics

This new #OpenAccess commentary by Wang et al. examines two recent studies that reveal essential #molecular processes that both trigger and prevent ETI, significantly advancing our understanding of #plant #immunity regulation.
https://doi.org/10.1111/jipb.13928
@wileyplantsci
#PlantSci #JIPB #pathogen #botany

Diagrams showing the various functions of sensor and helper nucleotide-binding leucine-rich repeats (NLRs) in effector-triggered immunity (ETI) and the molecular mechanisms that either activate or inhibit a helper NLR.

#Phytophthora infestans secretes numerous effectors to suppress #plant immunity. But how?
In a new #JIPB study, Liu et al. report that this devastating #pathogen targets host Rab-G3 GTPases with an atypical GTPase-activating protein.
https://doi.org/10.1111/jipb.13920
@wileyplantsci
#PlantSci #botany #OpenAccess

Image of a Nicotiana benthamiana plant with an inset from the infected portion of a leaf, illustrating the process by which P. infestans targets host Rab-G3 GTPases with an atypical GTPase-activating protein.

Medical and health research is vital to medicine and public health. There are already real world impacts felt around the country and around the world. People are dying, medical breakthroughs being delayed or prevented, and we are dismantling protections against #environmentalhazards. To put it in terms of money: health research grant money has a tangible #roi. It is not a money sink: we get more than we put in.

Access to healthcare is also being threatened with cuts to Medicaid which would prevent many who currently qualify from qualifying in the future. This means more #humans being kept from health insurance. A trip to the doctor is no longer a question of time or coinsurance but instead a decision between #life with crippling #debt or #death. #republicans are pushing for these cuts so their rich buddies pay even less in taxes and we can spend more the military. They are responsible for when you or your loved ones are faced with the decision between debt and death.

Please share and for those in the #usa #CallYourReps! And if a medical professional, researcher, or practitioner of some kind please sign.

https://docs.google.com/forms/d/e/1FAIpQLSdhq2St53gp-r08lhI_mHlKUhVxBXIv8EtomzOaHa9JILusow/viewform?usp=header

(apologies for the wall of hashtags)
#medical #Science #medicine #MedicalCare #researcher #HealthResearcher #HealthProfessional #health #health_research #research #Medical_research #funding #researchfunding #fundingcuts #researchgrants #NSF #hhs #USDepartmentofHealthandHumanServices #hhs_secretary #Robert_kennedy_jr #brainworm #cdc #TheCDC #centers_for_disease_control #osha #occupationalhealth #nih #nationalinstitutesofhealth #EnvironmentalScience #environmentalhealth #pollution #GOPLies #gop #medicalresearch #primarycare #pediatrics #pediatrician #nurses #nursing #congress #uspol #uspolitics #mikejohnson #project2025 #globalhealth #safety #HealthMonitoring #InfectionPrevention #pathogen #infectious_disease #vaccine #VaccineTrust #measles #MMR #mmr_vaccine #covid #LongCovid #cancer #cancer_immunology #cancertreatment #cancer_research #cancerresearch #MentalHeath #psychology #therapy #healthequity #Treatment #cure #trump #TrumpRegime #TrumpLies #budget #medicare #medicaid #cms #insurance #healthinsurance #access #healthcareaccess #medicaidcuts #taxbreaks #human_rights #humanrights

🚀🎉 Look out, world! We've invented a #super-speedy #pathogen #detector that works faster than your internet connection when trying to access this article! 😅🔍 But don't worry, you can still enjoy the thrill of getting blocked by our #cutting-edge #server #security instead! 🔒❌
https://phys.org/news/2025-05-mass-spectrometry-method-pathogens-minutes.html #technology #innovation #HackerNews #HackerNews #ngated

Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @PLOSBiology https://plos.io/4cINMpl

Top: Micrographs of fixed samples from each flask at the time of RNA harvest. Endospore release was first observed on day 3. Bottom: Schematic of Regulation of gene expression in Coccidioides development. The data uncover regulatory modules in Coccidioides development. The majority of Coccidioides transcription factors (TFs), depicted as triangles in the figure, show enhanced expression in spherules compared to hyphae. These TFs, along with RYP1 (green hexagon) and a second regulator whose motif is reported here, guide the expression of endospore-associated transcripts and secreted effectors, including proteases. RYP1 also controls a core regulon, that is, expressed in both spherules and hyphae via a canonical RYP1 motif. Finally, in arthroconidia, RYP1 impacts the transcriptome, but likely through indirect regulation of one or more additional key regulators.

🛡️Understanding #plant-#pathogen interactions will help us protect crucial #food #crops

🌾Shu et al. characterize a #MAPK signaling cascade that contributes to #wheat stripe rust resistance, providing new insights into crop immunity and the #pathogenicity of an obligate biotrophic #fungus.

https://doi.org/10.1111/jipb.13888
@wileyplantsci
#PlantSci #JIPB #botany

Impressive work by LetsAir👇 sharing solid info about #IAQ & #Airborne #pathogen mitigations. Another great part: they ask for & listen to feedback! 👏&🙏 Give them a follow, and share your comments/suggestions. (If you've been following their work, you'll recognize the evolution of their messages)

RE: https://bsky.app/profile/did:plc:xrv5zg56onyxihgy6sbn2kil/post/3lm5yj3j5ss2p

Plants use NLRs (intracellular immune receptors) to detect #pathogen effectors and restrict pathogen infection. In this fascinating new paper for #JIPB, An et al. share new insights into CNL-mediated immunity in Nicotiana benthamiana. https://doi.org/10.1111/jipb.13855
@wileyplantsci
#PlantSci #phytopathology #botany