LukHash Unveils "Chiptune Futurism" Expansion for Baby Audio BA-1
#LukHash #ChiptuneFuturism #BabyAudio #BA1 #Chiptune #RetroMusic #C64 #NES #Gameboy #8bitMusic #SoundDesign #MusicProduction #SynthPresets #RetroFuturism
https://theoasisbbs.com/lukhash-unveils-chiptune-futurism-expansion-for-baby-audio-ba-1/?feed_id=1321&_unique_id=67939e4fefa98

#SARS-CoV-2 #BA4/5 #infection triggers more cross-reactive FcγRIIIa signaling and #neutralization than #BA1, in the context of #hybrid #immunity, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00678-24?af=R

Although this is consistent with enhanced neutralization and FcγRIIIa signaling breadth of BA.4/5 vaccine boosters, the reduced activity against #XBB15 supports the need to update vaccines with XBB sublineage immunogens to provide adequate coverage of these highly antibody evasive variants.

Medical and Surgical Home, Catharine Place, Bath

https://ghostsigns.co.uk/2024/02/medical-and-surgical-home-catharine-place-bath/

The mysterious location of the Medical and Surgical Home ghost sign on Catharine Place, Bath. Photo: Tim Lindsay.

#BA1 #Bath #CatharinePlace #Ghostsign #Ghostsigns #Mystery #UK

@Brad LIES LIES LIES LIES LIES LIES LIES LIES LIES LIIIIIIIIIIIIIIEEEEEEEESSSSSSS!
Having had BA.1 1/2022 & nearly catching BA.5 via accidental 30 second exposure 7/2022🚪💨& observing my elderly neighbors throughout that summer who nearly caused me illness… a lack of immune response is NOT the flex everyone thinks it is

Body isn’t learning to “fight it off” but the exact opposite.. letting it in w/out a fight to destroy your #immuneSystem

I could write a tome about my observations I saw in 2022, especially the latter half

My obsession of how tf people weren’t showing symptoms began then. These people, 1 young & 1 old, got visibly very sick in November/December that year when enough of a mutated variant came along & got them

If #JN1 follows #BA1 pattern.. before July 2024 we will have an even bigger monster on our hands

Oh but wtf do I know🙄
https://www.nature.com/articles/s41564-023-01588-4

@EricCarroll @johnsnowproject
everything I’ve been thinking was in this article🖤& to see it all in one place…depressing &🥺💔

Having had #BA1 & #Wuhan via Italy strain, acute infection for both were remarkably similar in symptom & length, even post 2 Pfizer 4-6 months earlier

I believe we’ll eventually find out #omicron might be less instant fatal but long term more dangerous as #neurological #brainDamage issues become Dx in mass or visibly an issue through bizarre behavior in society

''... #neutralisation #assays using #vaccine #sera to assess the possibility that #BA286 evades the antiviral effect of vaccine-induced humoral immunity. The sera obtained from individuals vaccinated with third-dose monovalent, fourth-dose monovalent, #BA1 bivalent, and #BA5 bivalent mRNA vaccines exhibited very little or no antiviral effects against BA.2.86.''

Global #COVID monitoring is crashing as BA.2.86 #COVIDvariant raises alarm
The number of mutations in #BA2.86's critical #spikeprotein is over 30, rivaling the number seen in the original omicron subvariant, #BA1, which went on to cause a tidal wave of cases and hospitalizations. The spike mutations appear geared toward evading neutralizing #antibody protections built up from past infections and #vaccinations.
"This is on the shoulders of governments right now." https://arstechnica.com/health/2023/08/global-covid-monitoring-is-crashing-as-ba-2-86-variant-raises-alarm/

Free #RStats internals idea:

Add support for 3-digit hex colours e.g. "#ba1"

File to change: src/library/grDevices/src/color.c

Need to
* add a "case 4:" to the switch statement
* Write 4 lines of code. (including a break statement)
* Change Line:1365 to include case when strlen = 4

Anyone else annoyed by this?

[Articles] #Omicron #BA1-containing #mRNA-1273 #boosters compared with the original #COVID19 #vaccine in the #UK: a randomised, observer-blind, active-controlled trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00295-5/fulltext?rss=yes #prevention #publichealth #rct

#BA1 Bivalent #COVID-19 #Vaccine Use and #Stroke in #England, JAMA: https://jamanetwork.com/article.aspx?doi=10.1001/jama.2023.10123

''In this study, the authors isolated and characterized neutralizing antibodies from vaccinated individuals with #SARS-CoV-2 #BA1 breakthrough infection and show that elite antibodies derived from specific germlines provide potent pan-variant neutralization capacity and in vivo protection.''

Neutralising #immunity to #omicron sublineages #BQ11, #XBB, and #XBB15 in healthy #adults is boosted by bivalent #BA1-containing #mRNA #vaccination and previous Omicron infection, https://doi.org/10.1016/S1473-3099(23)00289-X

Kaku, C.I., Starr, T.N., Zhou, P. et al. #Evolution of #antibody #immunity following #Omicron #BA1 breakthrough infection. Nat Commun 14, 2751 (2023). https://doi.org/10.1038/s41467-023-38345-4

#Immunity of heterologous and homologous boosted or #convalescent individuals against #Omicron #BA1, #BA2 and #BA4/5 variants https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad057/7069351?rss=1

{#SARS-CoV-2 #Omicron} #BA1, #BA2 and #BA275 variants show comparable #replication kinetics, reduced impact on #epithelial #barrier and elicit cross-neutralizing #antibodies https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011196

https://www.news-medical.net/news/20230201/New-study-suggests-Omicron-BA1-breakthrough-infection-drives-long-term-remodeling-of-memory-B-cell-repertoire-in-vaccinated-populations.aspx
#BA1
think these studies are all supposed to be “comforting & reassuring” but having had #sarscov2 1.0 aka🇨🇳via🇮🇹then 2 #Pfizer & then BA.1…

trust my remodeled #bCells as much as I trust my psychopath 1/2 brother🙄,which is to say, negative quadrillion

BA.1 drove me into 24/7 obsession w/ #reinfection & all things #Covid

& after barely escaping BA.5 imo it’s either avoid like the Plague it is or suffer lifelong consequences
We need updated & better #vaccines #Novavax 💉💉💉💉

DE: #Herzmuskelzellen hören früher auf zu schlagen – #Omicron-#Subvariante BA.5 schädigt #Kardiomyozyten stärker als BA.1 https://www.mittellaendische.ch/2023/01/26/de-herzmuskelzellen-h%C3%B6ren-fr%C3%BCher-auf-zu-schlagen-omicron-subvariante-ba-5-sch%C3%A4digt-kardiomyozyten-st%C3%A4rker-als-ba-1/ #BA1 #BA5 #CovidIsNotOver #Corona #Pandemie #Wissenschaft #Forschung #Fakten #DMZ

#Spike and #nsp6 are key determinants of #SARS-CoV-2 #Omicron #BA1 #attenuation https://www.nature.com/articles/s41586-023-05697-2

#Protection conferred by #Delta and #BA1 / #BA2 #infection against #BA4 / #BA5 infection and #hospitalization: A Retrospective Cohort Study, The Journal of Infectious Diseases, jiad003, https://doi.org/10.1093/infdis/jiad003

A vaccine-only strategy, needs a vaccine that works. We don't know yet, how effective #Bivalent booster (#Omicron #BA1 or #BA5) is in preventing #XBB15 infections and severe outcomes.