#Sequencing

2025-10-07

My PhD student authored a rather niche piece of software written in Rust that introduces a new type of index for BAM files, allowing fast counting and filtering of reads based on their FLAG attributes:

researchgate.net/publication/3

Although we mention possible usage scenarios, we are far from sure how frequent, or useful these might be. Would be grateful for any input on this from the community, especially from people who can imagine including #bafiq in their pipelines or BAM file repositories. Negative examples might also help.
#bioinformatics #genomics #sequencing #genome #samtools

2025-09-27

Does anyone have experience with the new ultima genome sequencing technology? Does it compare well to illumina?

It is apparently cheaper , but I was not sure about the quality.

#genomics #sequencing #omics #illumina

Moreno Colaiacovo 🇪🇺emmecola@mastodon.uno
2025-08-01

#EU law requires #GMO labeling when levels exceed 0.9% at the ingredient level.

Our study shows that duplex #sequencing can reliably detect #NGT genome-edited DNA down to 0.1%, suggesting a potential alternative detection approach when #PCR assay design is not feasible. 🧬🔎

tinyurl.com/duplexNGT

Our paper on duplex sequencing approach for high-sensitivity detection of genome-edited plants
2025-07-23

Minimod preprint from @hasindu2008 gang is out. Code available github.com/warp9seq/minimod

I love the work they're doing with slow5/blow5 open spec for ONT raw data, and archive all internal reads using them. Really need to sit down and test this one out with my #archaea raw data!

#bioinformatics #methylation #ONT #sequencing

2025-07-10

The next awardee that we hear from is Rochelle Chan, who was awarded this year's Huntingford Medal, which is awarded to the most impactful paper in the Journal of #Fish Biology last year. Rochelle's paper utilises minion #sequencing and COI barcoding to identify species from #larvae in a high throughput manner #FSBI2025 #JFB Read Rochelle's paper, here: doi.org/10.1111/jfb.15920

2025-07-10

"Researchers have described proteins that they say are among the most ancient ever sequenced. Two teams, which analysed molecules from extinct relatives of rhinos and other large mammals, have pushed back the genetic fossil record to more than 20 million years ago."

nature.com/articles/d41586-025

#Proteins #Prehistory #Sequencing #Mammals

2025-07-08

First #cDNA @nanopore work I contributed to
Nano3P-seq: charting the coding and noncoding transcriptome at single-molecule resolution
#sequencing #poly_a_tail
nature.com/articles/s41596-025

2025-06-26

New #ISEPpapers! New T2T assembly of #Cryptosporidium parvum IOWA II annotated with Legacy-Compatible Gene identifiers nature.com/articles/s41597-025

#Protists #Microbes #Parasites #Genomics #Bioinformatics #Genome #Sequencing

a figure from a scientific article showing various aspects of a genomic assembly
El Pregoner del Metallpregonermetall
2025-06-10

SEQUENCING (Ucraïna) presenta nou single: "Втрачена земля"

2025-06-03

Our poster abstract for #ASMicrobe2025 is up! First bit of info from our warehouse lab led Haloarchaea study project. Session EEB-P-302 - EEB02 Saturday Microbial Evolution. Please feel free to come say hi 👋

#microbiology #archaea #sequencing #methylation

abstractsonline.com/pp8/#!/209

2025-06-02

1 of 2 posters for the summer picked up! I'll be presenting this one at upcoming Boston Bacterial Meeting #BBM2025.

A specific type of plasmid replication gene (RPA) is overreprented among Deinococcota & analysis hints at introduction of the MGE early in its history, tracing back to Allomeiothermus #microbiology #amateurbiology #sequencing

Since this is polishing up of such an older data, I'd say it's the most amateur-like (in a good way) of all stuff coming out of our warehouse lab right now

Poster "RPA plasmid replication mechanism is conserved across members of phylum Deinococcota, suggesting origin from a common ancestor"
Leibniz-Institut DSMZdsmz@wisskomm.social
2025-05-28

Kurze Erinnerung: Noch könnt ihr euch für ein Gespräch mit den DSMZ-Forschenden zu den diesen Themen anmelden 👇

Anmeldung: leibniz-gemeinschaft.de/ueber-

#BookAScientist #ernährung #pflanzengesundheit #pflanzenviren #phagen #antibiotika #gesundheit #cassava #sequencing

Leibniz-Institut DSMZdsmz@wisskomm.social
2025-05-23

Wondering how plant virus detectives work? Ask our expert Paolo Margaria at #BookAScientist.
appointments: leibniz-gemeinschaft.de/ueber-

#sequencing #plantvirus #hightroughput

John Vaccaro (johniac)johniac
2025-05-13

SciTech Chronicles.. . . . .May 13th, 2025

bit.ly/stc051325

#"lime clasts" #"hot mixing" #"genetic material" #"1000 Genomes Project" -powered

2025-05-08

ONT is finally fully discontinuing the original MinION Mk1B model (the original silver stick we're all familiar with). End of en era. I hope at least some future flow cells will continue to be compatible with the older platform 😔

#microbiology #sequencing #bioinformatics

2025-04-18

Whole genome #sequencing has become cheap enough to become a routine early diagnostic test for #rareDiseases. This can help patients to avoid years of fruitless diagnostic odyssey. Could also facilitate development of cures. Moving case report. nature.com/articles/d41586-025

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