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Recent studies explore a novel approach to control parasitic #plants by manipulation rather than #biosynthesis of #strigolactone exudation.
Learn more about this potential #CropScience breakthrough in a new #JIPB commentary.🔓⬇️
https://doi.org/10.1111/jipb.13937
@wileyplantsci
#PlantSci #botany

Diagram to illustrate how modulation of strigolactone (SL) exudation in crops balances the relationship between phytoparasite management and crop growth and yield.

Most #biosynthetic gene clusters remain uncharacterized. @marnixmedema @gillesvanwezel &co integrate #GRN analysis & global expression data to identify desJGH as an operon essential for #biosynthesis of #desferrioxamineB in Streptomyces @PLOSBiology https://plos.io/43UVUPB

Left: Predicted gene regulatory network of Streptomyces coelicolor based on 17 well-known regulators. Each node in the network represents a (regulatory) gene, and every edge represents a PWM predicted regulatory interaction between nodes. The edges colored in dark gray indicate strong PWM prediction scores, while the lighter gray shades represent weaker interactions. Matches within BGC regions are depicted as triangles. In six regions (black circled), the matches fall within a co-expressed region, highlighting their functional relation to these compounds. Right: Proposed biosynthetic pathway for assembly of desferrioxamines E and B. Main biosynthetic enzymes presented in bold face. DesG and DesH balance intracellular N-hydroxy-N-succinylcadaverine (HSC) and N-hydroxy-N-acetylcadaverine (HAC) concentrations by converting HSC to HAC. In the absence of DesG and/or DesH, the cells likely fail to produce sufficient levels of HAC, thereby strongly attenuating the production of DFOB. Although DesC has been shown to be able to catalyze the acetylation of N-hydroxycadaverine in vitro, the enzyme can only modestly compensate for the loss of DesH in vivo, underlining the important role played by DesG and DesH in DFOB production.

Cai et al. shine a light on #chloroplast-produced ROS #biosynthesis in #plant #immunity, with new findings that HHL1 modulates AvrRpt2-triggered immunity by regulating ROS homeostasis in a light intensity-dependent manner.
https://doi.org/10.1111/jipb.13929
@wileyplantsci
#PlantSci #JIPB #botany

Diagram illustrating that under normal light conditions, HHL1 positively regulates AvrRpt2-mediated immune responses, but under high light stress, it has a negative regulatory effect.

3-Jun-2025
Two plant species invent the same chemically complex and medically interesting substance
The elucidation of the biosynthetic pathway of #ipecacuanha #alkaloids shows how two distantly related plant species could develop the same substance independently

https://www.eurekalert.org/news-releases/1085960 #science #plants #bioactives #biosynthesis #evolution #plantPhysiology

Serious question...can #SweetPotato get any better?
Fan et al. think so! They recently identified a natural allelic variant in the promoter of IbNAC22 that regulates #starch #biosynthesis and is a candidate #gene for crop improvement!
https://doi.org/10.1111/jipb.13916
@wileyplantsci
#PlantSci #JIPB #botany

Diagram of a cell cross-section focused on component interactions between the cytoplasm, nucleus, and amyloplast. Annotations indicate that overexpression of IbNAC22 improves starch and amylose contents, IbNAC22 directly activates the expression of IbGBSSI, a key gene for amylose biosynthesis but suppresses the expression of IbSBEI, a key gene for amylopectin biosynthesis. IbNAC22 directly interacts with IbNF-YA10, while overexpression of IbNF-YA10 significantly improves starch and amylose contents.

Biosynthesis of ascorbic acid in animals and plants
Only humans cannot synthesize ascorbic acid, but plants and animals are very good at this task. In plants, biosynthesis begins with D-glucose, D-fructose is obtained, after D-mannose, from which, through other processes, ascorbic acid is obtained.
In animals, this process occurs differently, everything starts with D-glucose and ends with ascorbic acid.

#ascorbicacid #biochemistry #vitaminc #Biosynthesis

New publication: Biomimetic Total Synthesis and Paired Omics Identify an Intermolecular Diels-Alder Reaction as the Key Step in Lugdunomycin Biosynthesis. #bacteria #biosynthesis #chemicalreactions #genetics
https://doi.org/10.1021/jacs.5c01883

Graphical abstract Uiterweerd et al. (2025).

Mapping the #yerba_mate #genome reveals surprising facts about the #evolution of #caffeine.

#Ilex #genome_duplication #biosynthesis

https://phys.org/news/2025-02-yerba-genome-reveals-facts-evolution.html

Understanding the complex mechanisms behind #seed oil #biosynthesis regulation provides insights and strategies for improving oil production and stress tolerance in #oil #crops.
Wei et al. explore what we know in a new #JIPB review!
https://doi.org/10.1111/jipb.13834
@wileyplantsci
#PlantSci #botany

Diagram representing the complex regulatory network governing seed oil biosynthesis.

Derivatives of #casbene and #neocembrene play significant roles in #plant defense and have #pharmaceutical applications. Understanding the #metabolic pathways and #evolutionary history governing the #biosynthesis of these compounds offers resources for #crop breeding.
https://doi.org/10.1111/jipb.13836
@wileyplantsci
#PlantSci #botany

This flow diagram illustrates that rice sesquiterpene synthase OsTPS10 is conserved in monocots and first appeared in wild rice, whereas the casbene-type diterpene synthases OsTPS2 and OsTPS28 sequentially evolved through gene duplication, transit peptide recruitment, and mutation of key amino acids such as H362R.

Ravi Gupta discusses the recent identification of #HydrogenPeroxide as a systemic acquired #resistance-inducing signal and its dose-dependent effect on systemic tissue SA #biosynthesis in response to #pathogen attack.
https://doi.org/10.1111/jipb.13833
@wileyplantsci
#PlantSci #JIPB #botany

Diagram of the proposed mechanism by which hydrogen peroxide functions as a systemic acquired resistance-inducing signal and its dose-dependent effect on salicylic acid biosynthesis in the systemic tissues in response to a pathogen attack.

#Microbial #cell factories may help get to the root of understudied #plant #molecules

#metabolomics #biosynthesis #strigolactones

https://phys.org/news/2025-01-microbial-cell-factories-root-understudied.html

I am thrilled to announce that our lab has joined @Uni_Stuttgart and I have accepted the position as Professor of Technical Biochemistry! 🔬🥂 I am honored to follow in the footsteps of Prof. Bernhard Hauer, whose contributions to the field are truly inspiring.
We look forward to continue working on #EnzymeDesign, #Biocatalysis, #Biosynthesis and #NonribosomalPeptides. Thanks to Dr Kirti Sharma, Maximilian Müll, and Kexin Zhang for joining me on the journey from @LeibnizHKI to Stuttgart.

⏳New year, new #PlantScience!🥳
#Starch #biosynthesis is critical for🍞#wheat quality and yield. Here, Liu et al. reveal the crucial role of TaDL and identify the elite allele TaDL-BI associated with starch content. 👇🔓https://doi.org/10.1111/jipb.13815
@wileyplantsci
#JIPB #CropSci #PlantScience #botany #OpenAccess

Image of a single grain of wheat with superimposed flow chart annotations illustrating how TaDL physically interacts with TaB3 and TaNF-YB1, binding directly to the promoter region of genes involving starch biosynthesis--promoting starch synthesis and improving grain quality.

🌽#Maize #plants produce #terpene compounds when attacked by Asian corn borer larvae, but when #genes involved in #biosynthesis of these plant volatiles are knocked out, plants are made less attractive to herbivory.🔓⬇️
https://doi.org/10.1111/jipb.13763
@wileyplantsci
#JIPB #PlantSci #openaccess #botany

Diagrams comparing WT and cyp92c5 cyp92c6 mutant plants to illustrate that plant terpenes DMNT and TMTT function as signaling compounds that attract Asian corn borer (Ostrinia furnacalis) to maize plants.

Cytokinin Oxidase/Dehydrogenase as an Important Target for Increasing Plant Productivity - #cytokinins #biosynthesis #degradation #cytokininoxidase #dehydrogenase #CKO #CKX #CKXgenes #activityregulation #abioticstresses #resistance #productivity - https://link.springer.com/article/10.3103/S0095452724020051

In a new study published by #JIPB, Zhang et al. shed light on CASPL functions and the #molecular machinery behind secondary #cell wall #biosynthesis in #cotton fibers. Free to read right here!👇
https://doi.org/10.1111/jipb.13777
@wileyplantsci
#PlantSci #botany

Cross section of the cell wall and plasma membrane of WT and ghcaspl1 ghcaspl2 cotton fiber cells to illustrate how the cellulose synthase complex–interacting factor CASPARIAN STRIP MEMBRANE DOMAIN-LIKE1 stabilizes the cellulose synthase complex on the plasma membrane, thus playing a crucial role in regulating secondary cell wall thickening in cotton fibers.

Find out which #cytochrome P450 is responsible for the de novo #biosynthesis of two types of aporphine #alkaloid in #yeast!
Li et al. lay a foundation for using #SynBio to produce these valuable compounds.
https://doi.org/10.1111/jipb.13724
@wileyplantsci
#JIPB #PlantSci #pharmacology #botany #syntheticbiology

Diagram of yeast, illustrating the biosynthetic pathways for the two types of aporphine alkaloids in budding yeast (Saccharomyces cerevisiae) for the de novo production of compounds such as (R)-glaziovine, (S)-glaziovine, and magnoflorine.

#Biosynthesis of #cellulose, #lignin, and #hemicelluloses in #plants is regulated by a transcriptional regulatory network featuring orthologous shared TFs of #poplar and #Arabidopsis.

#Wood you like to know more?😉https://doi.org/10.1111/jipb.13717
@wileyplantsci
#PlantSci #JIPB #forest #botany

Similarities and differences in the hierarchical transcriptional regulatory network that produces biosynthesis of cellulose, lignin, and hemicelluloses in plant secondary cell walls of Arabidopsis (left) and poplar (right).

#Artemisinin is an important anti-#malarial #drug compound produced by the glandular #trichomes of sweet #wormwood.
He et al. report that the AaBBX21–AaHY5 module mediates its #light-regulated #biosynthesis in A. annua
https://doi.org/10.1111/jipb.13708
@wileyplantsci
#JIPB #PlantSci #botany

#biosynthesis

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