Lmst

Reproductive #aging is associated with declining #fertility and increasing #inflammation. @spangas &co explore a @PLOSBiology study that uses cutting-edge tech to characterize the role of multinucleated giant cells in #ovarian aging. Paper: https://plos.io/3T84WE0 Primer: https://plos.io/3HXKN1b

In ovaries collected from mice and nonhuman primates (NHPs), MNGC penetrance increases with reproductive age (left panel). Transcriptomic profiling of MNGCs reveals the top gene categories as degradation, energy production, and immune processes (right panel top left section). Further, MNGCs are closely associated with T-cells (right panel top right section). Additional transcriptomic analysis segregates MNGCs from macrophages and stromal cells. While stromal cells serve as controls and do not overlap with macrophages or MNGCs, macrophages and MNGCs share expression of macrophage marker F4/80. However, the authors identify Gpnmb as a unique, putative marker of ovarian MNGCs (right panel bottom section). Created in BioRender

Freezing eggs may give people more choices, says CPC-CG member Bernice Kuang in today's Financial Times.

"It may also take pressure off partnerships formed later in life, and give young people time to settle into relationships instead of feeling rushed to make partnership decisions."

Full story: https://www.ft.com/content/c5631c41-5b23-4f3c-8807-1372c9377845

#IVF #fertility #fertilityissues #olderparents #family #relationships #socialscience #demography

California’s much-touted IVF law may be delayed until 2026, leaving many in the lurch

California lawmakers are poised to delay the state’s much-ballyhooed new law mandating in vitro fertilizatio…
#UnitedStates #US #USA #america #California #Embryo #fertility #Fertilization #GavinNewsom #HealthCare #immigrationprotests #invitro #Infertility #IVF #LAimmigrationprotests #LAprotests #losangeles #NationalGuard #Sperm #unitedstatesofamerica #USnews #USAnews #uterus
https://www.europesays.com/2192414/

Searching for the best #IVF center in Pune?

Wombs Fertility & Reproductive Health Clinic offers advanced and compassionate #fertility solutions to help you achieve your dream of parenthood. Our experienced specialists provide personalized IVF treatments, utilizing state-of-the-art technology and a holistic approach to maximize your chances of success. Discover more about our fertility expertise and services at: https://maps.app.goo.gl/qjPnNPgJz3uoeDta6

How do declining #fertility and #climatechange interact?

https://marginalrevolution.com/marginalrevolution/2025/06/how-do-declining-fertility-and-climate-change-interact.html

Mediterranean diet boosts sperm health while ultra-processed foods lower fertility, study finds

New …
#dining #cooking #diet #food #MediterraneanDiet #cell #Fertility #Genetic #Hormone #Infertility #MaleInfertility #Mediterranean #minerals #Morphology #nutrients #Pregnancy #ReproductiveHealth #Research #Semen #Sperm #testosterone #ultraprocessedfoods #Vitamins
https://www.diningandcooking.com/2142943/mediterranean-diet-boosts-sperm-health-while-ultra-processed-foods-lower-fertility-study-finds/

Italy pioneers subsidised egg-freezing to tackle its demographic crisis.

The southern region of Puglia and central government offer differing initiatives to reverse country’s falling birth rate.

Puglia is pioneering subsidised egg-freezing for healthy women, while the central government is planning to promote fertility testing — the latest initiatives aimed at improving the country’s precipitous birth rate.

https://mediafaro.org/article/20250621-italy-pioneers-subsidised-egg-freezing-to-tackle-its-demographic-crisis?mf_channel=mastodon&action=forward

#Italy #Demographics #IVF #EggFreezing #Fertility

Unlocking #Parenthood The Real #Fertility Crisis

https://indianf.com/unlocking-parenthood-the-real-fertility-crisis/

New work by Gong et al. on FGM1/rPPR4 in #Arabidopsis reveals that essential mechanisms are established during female gamete maturation to provide a #molecular basis for #seed #development initiation and #plant #fertility.
https://doi.org/10.1111/jipb.13922
@wileyplantsci
#PlantSci #JIPB #botany

Egg cell and endosperm GFP micrographs of WT and mutant plants illustrate that FEMALE GAMETE MATURATION 1/PENTATRICOPEPTIDE REPEAT PROTEIN 4), a component of the mitochondrial ribosome large subunit, directly interacts with another mitochondrial protein GAMETE CELL DEFECTIVE 1 to play an essential role in maturation of the egg cell and central cell.

📰 "Mating status drives fitness tradeoffs in exercised female Drosophila"
https://www.biorxiv.org/content/10.1101/2025.06.11.659196v1?rss=1
#Drosophila #Fertility

📰 "Ataxin-2 preserves oocyte genome integrity by promoting timely premeiotic DNA replication"
https://www.biorxiv.org/content/10.1101/2025.06.13.659559v1?rss=1
#Drosophila #Fertility #Genomics

Kids: The New Investment? - Naval on Modern Wisdom

#fertility #incentives #economics #children

🔖 NEW findings from the ESRC-funded FertilityTrends project

The first study to examine how having children in Britain has changed over 3 decades, by child order (1st, 2nd, 3rd, etc.), and to compare these changes between England & Wales and Scotland

➡️Article: https://doi.org/10.1080/00324728.2025.2491354

#fertility #birthorder #demography #population #populationstudies #socialscience #family #havingchildren #birthrates

Image shows web page for the Population Studies: A Journal of Demography article on Long-term fertility trends by birth order in Britain: Comparison between England & Wales and Scotland
Hill Kulu, Bernice Kuang, Sarah Christison & Ann Berrington
Received 11 Mar 2024, Accepted 10 Dec 2024, Published online: 12 Jun 2025

Abstract
This study uses census-linked administrative data to investigate childbearing trends by birth order in Britain over three decades. This is the first study to investigate longer-term changes in fertility dynamics in Britain by birth order and to compare parity-specific fertility by country. First-birth rates declined in the 1990s, slightly increased in the first decade of this century, and decreased thereafter, with changes in timing of parenthood responsible for these changes. Second- and third-birth rates declined in the 1990s but remained relatively stable in the early twenty-first century. Birth intervals remained unchanged, meaning that changes in quantum are responsible for trends in higher-order birth rates. Time trends are similar in England & Wales and Scotland but with significantly lower second- and third-birth rates in Scotland. Changes in population composition by education and ethnicity explain little of the aggregate fertility trends or between-country differences. Both countries have seen rapid declines in first-birth rates, especially among low-educated women.

Global #Human #Fertility rates have been in an unprecedented decline, falling from 5.3 births per woman in the 1960s to 2.3 in 2023.

Despite this declining fertility, the human population continues to grow, projected to reach a peak of around 10.3 billion in the mid-2080s before a gradual decline begins.

https://knowledgezone.co.in/trends/browser?topic=Human-Population

4 #Paradoxes That Will Expand Your #Thinking : Medium

Why your next #Flight could be a lot #Bumpier : Misc

#World #Fertility rates in '#Unprecedented decline', #UN says : BBC

Check our latest #KnowledgeLinks

https://knowledgezone.co.in/resources/bookmarks

Why are people having fewer children? ‘Financial limitations’ a top barrier #Economy #Lifestyle #World #Birth Rates #Family Planning #Fertility

https://globalnews.ca/news/11234004/fertility-children-families-un-report-reasons//612

🗞️🗞️ “While some individuals [in the UK] desire to remain #childfree, evidence suggests there are a significant number who want #children but are currently unable to have them,” said CPC-CG member Ann Berrington commenting on a new #UN report on global #fertility in today's #FinancialTimes, citing #economic, #health or #partnership reasons
https://www.ft.com/content/1559b9df-0f76-4c50-baa4-32242d2fdea0

Africa: The Fertility Fallacy - Five Things You Didn't Know About Global Fertility Rates: [UNFPA] United Nations, New York -- "Do you want kids?" Every day, people around the world ask themselves, and others, this question. But it also begs another: "Do you feel able to have children?" http://newsfeed.facilit8.network/TLGKxm #Fertility #GlobalFertility #FamilyPlanning #Childbirth #Parenting

📰 "Evidence for Transcriptomic Conservation Between the Main Cells of the Drosophila Prostate-Like Accessory Gland and Basal Cells of the Mammalian Prostate."
https://www.biorxiv.org/content/10.1101/2025.06.05.658085v1?rss=1
#Drosophila #Fertility #Adult

#fertility

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