#MS

Gregory MSgregory_ms
2025-12-10

gregory-ms.com/articles/309496

Nicotinamide adenine dinucleotide (NAD +) supplementation attenuates demyelination in the experimental autoimmune encephalomyelitis model.

Gregory MSgregory_ms
2025-12-10

gregory-ms.com/articles/309500

Tregs suppress the pro-inflammatory activity of DCs while promoting the generation of a tolerance-inducing DC phenotype. iTregs exhibit greater efficacy in mitigating brain inflammation in both EAE and EAE provoked by a high-salt diet.

Killer Rabbit 90killer_rabbit90
2025-12-10
Gregory MSgregory_ms
2025-12-09

gregory-ms.com/articles/309387

Multiple sclerosis (MS) is an autoimmune condition characterized by myelin destruction and neurodegeneration. Fisetin has a potential neuroprotective effect in CPZ model of MS and can be studied as an adjuvant therapy to enhance remyelination and mitigate disability in MS patients.

Steve Hill 🏴󠁧󠁢󠁷󠁬󠁳󠁿🇪🇺steve@mastodon.nexusuk.org
2025-12-09

Arrgh, #Microsoft

They have an "endpoints API" that has a machine readable list of endpoint IPs for #MS products. It does not mention #Teams, but does list #Skype. None of those IPs appear to be used by Teams.

There's a human-readable page with Teams endpoints, which are the same IPs listed for Skype above.

There's a human-readable page for "Azure Communications Services". Does not mention Teams, but lists IPs Teams seems to use. There is no machine-readable version.

2025-12-07

MS has taken a lot from me, but it can’t take away these memories.

I did this shit.

#FuckMS #MS #MultipleSclerosis

It’s a lanky guy wearing a blue MS Trust vest and a blue tutu. He’s raising a finger in the air and has Buckingham Palace behind him as he enters the last mile or so of the London Marathon in 2016. My left leg is heavily strapped to keep my shitty ankle working for as long as possible.A lanky guy with a big goofy grin wearing sunglasses and a Rushcliffe Athletic Club vest. He’s bathed in a lovely warm evening sunshine glow and is running around Holmepierrepont Lake as part of a summer league club running event.Bald, lanky guy wearing an RAC club vest and powering up a muddy hill at a cross country race. This was a two lap course, and literally half the course was shin deep in cheesy, stagnant water. I loved it!About 22 miles into the Liverpool Marathon in (I think) Sefton Park. I’m running with my wife and we both have our arms spread out wide and we look deliriously happy. We’re both wearing blue MS Trust vests and blue tutus. My knee and leg are very heavily strapped. For some reason, between April 2018 and April 2019, I ran four full marathons and raised about £40,000 for the MS Trust. I was even featured in the Daily Mirror, but less I felt special, the runner profiled underneath me was running without kidneys. The bloody show off.
2025-12-07

I used to run marathons and now find running incredibly difficult. I do still run (after a fashion), and I row and swim and things. I’m pretty active, and I try to look forwards and to be positive…. But sometimes it’s hard.

#FuckMS #MS #MultipleSclerosis

2025-12-07

I went for a walk this morning as the river is still a bit high for rowing and I needed some extra sleep. I took my walking poles today, and managed another 5km or so. I was limping pretty badly by the end and relying on the poles to walk straight. But hey… done. Got some high ratio 1ks on the erg tomorrow evening, so mustn’t grumble, eh?

#FuckMS #MS #MultipleSclerosis

Retro Game BotRetrogamebot
2025-12-07

🎮 Random Retro Game:

Title: Ms. Pac-Man
Released: 1981-01-12
Platforms: Game Boy, NES, SEGA Master System, Game Gear
Also released on: PC, Xbox One, PlayStation 4, iOS, Android, Xbox 360, Xbox, SNES, Apple II, Commodore / Amiga, Atari 7800, Atari 5200, Atari 2600, Atari 8-bit, Atari Lynx, Genesis

.Pac-Man

Cover image of Ms. Pac-Man

Mindful Practices for Chronic Pain Relief and Emotional Wellness

Photo by Keenan Constance on Pexels.com

Chronic pain manifests in various forms, complicating life and diminishing joy. Whether stemming from autoimmune diseases, arthritis, fibromyalgia, or other chronic conditions, it not only impacts physical health but also has profound emotional and psychological effects that can lead to feelings of isolation and hopelessness. This multifaceted experience often challenges our daily routines, leading individuals to navigate a world that frequently seems unforgiving. To counteract these struggles, embark on a gentle meditative journey that encourages us to fully experience the body as it is, without judgment, and to cultivate awareness of our inner sensations and emotional states. By incorporating techniques such as mindfulness and visualization, we can ease our pain through the transformative power of gratitude, fostering a deeper connection with ourselves and nurturing resilience amidst adversity.

Body Scan

A body scan incorporated into meditation can be a gentle way to ease chronic pain, offering a pathway to greater mindfulness and enhanced body awareness. As we embark on a body scan, we lovingly direct our attention to various parts of our body, acknowledging sensations or tension without judgment. This compassionate practice allows us to recognize and alleviate the anxiety and stress that often accompany chronic pain, paving the way for a more peaceful experience. By embracing relaxation, we help to release muscle tension and foster a deeper connection with ourselves, empowering us to manage our pain responses more effectively. As we cultivate acceptance and compassion towards our pain, we may discover a reduction in discomfort and an uplift in our overall well-being.

Photo by Elina Fairytale on Pexels.com

Visualization

Visualization in meditation can be a powerful ally in easing chronic pain, as it fosters a gentle mental picture of relaxation and healing, potentially transforming the way we experience pain. By engaging in focused imagery, we can nurture our minds, leading to a reduction in stress and an increase in the release of endorphins, the body’s natural pain relievers. This calming approach allows patients to create a distance from their discomfort, offering a renewed sense of control over their pain management journey. Moreover, visualization techniques can deepen mindfulness, empowering individuals to navigate their pain more effectively by reshaping emotional responses and alleviating anxiety tied to chronic conditions.

Affirmation

Affirmations like: I am in control of my body; Each breath brings me healing and relaxation; Pain is a temporary experience; I am strong and resilient; I embrace comfort and release tension, can genuinely transform how we perceive chronic pain by nurturing a sense of empowerment and mindfulness. By regularly uttering these gentle affirmations, we can forge a deeper bond with our physical sensations and emotional states. This nurturing practice invites a shift from seeing pain merely as an enemy to acknowledging it as a part of their unique journey, fostering personal growth and resilience. Furthermore, embracing the transient nature of pain can cultivate a profound appreciation for moments of relief, ultimately enhancing one’s overall well-being. In the end, such affirmations help to create a compassionate mental space where hope and positivity can blossom, leading to improved coping strategies and a more fulfilling life, even amid the challenges of chronic pain.

Gratitude

Photo by Summer Stock on Pexels.com

These tools offer unique ways to navigate the challenges of chronic pain, allowing glimmers of hope to shine through the clouds of distress we may face each day. I can personally empathize with how challenging it can be to cultivate gratitude during flare-ups. When caught in the grip of intense pain that lasts for hours, days, weeks, or even longer, it feels nearly impossible to foster a sense of thankfulness. Yet, I’ve discovered that embracing gratitude can be a crucial aspect of coping with chronic illness over the long haul.

Expressing Gratitude in Coping with Chronic Pain

Daily expressions of gratitude can be a powerful tool for managing chronic pain, offering both emotional and psychological benefits. When we take the time to acknowledge and appreciate the positive aspects of our lives, we effectively shift our focus away from pain and discomfort. This shift can create a sense of balance, allowing for moments of joy and contentment to emerge even amidst the challenges posed by chronic conditions.

Fostering a Positive Mindset

Gratitude encourages a positive mindset, which can significantly influence how we perceive and react to pain. By actively recognizing the things we are thankful for—be it supportive relationships, small victories, or moments of beauty in our daily lives—we create a mental buffer against negativity. This approach can lessen the impact of chronic pain symptoms and foster resilience, enabling us to navigate our circumstances with greater strength.

Enhancing Emotional Well-being

Chronic pain often comes with emotional burdens, such as frustration, sadness, and isolation. Practicing gratitude can counter these feelings by anchoring us in a place of appreciation and hope. Frequent acknowledgment of what we are grateful for helps to rewire our internal dialogue, promoting feelings of empowerment and control over our life experience. This emotional shift can lead to reduced anxiety and an overall enhanced sense of well-being.

Building Connections

Photo by Thirdman on Pexels.com

Expressing gratitude can also strengthen social connections. When we share our gratitude with others, we open up opportunities for connection and support. This network can be vital for individuals dealing with chronic pain, as it fosters a sense of belonging and understanding. Engaging with empathetic friends, family, or support groups can enrich our coping strategies and provide avenues for sharing experiences and feelings.

Cultivating Mindfulness

Incorporating gratitude into our daily routine encourages mindfulness, prompting us to be present in the moment. This practice allows us to observe our thoughts and feelings about pain without judgment. By integrating gratitude moments into mindfulness exercises, we can deepen our awareness of both our pain and our capacity for joy, creating a holistic approach to managing chronic pain.

Developing Resilience

Photo by Andrea Piacquadio on Pexels.com

Finally, gratitude cultivates resilience. By focusing on the positive aspects of our lives, we can better adapt to the challenges posed by chronic pain. This resilient mindset not only helps us endure difficult moments but also empowers us to explore solutions and treatments that enhance our quality of life. Embracing gratitude invites us to see beyond our present struggles and fosters hope for healing and growth.

Daily expressions of gratitude are a transformative practice for coping with chronic pain. By fostering a positive mindset, enhancing emotional well-being, building connections, cultivating mindfulness, and developing resilience, we can navigate our journey with greater clarity and strength, ultimately leading to a more fulfilling life.

https://open.spotify.com/episode/0aAbwS4h06BaL9GSyYlaQk?si=AdV1LU1yRh6bZ-18fzWp_A

Discover the beauty of resilience as you immerse yourself in this soothing guided meditation, thoughtfully designed to ease the physical and emotional burdens of chronic pain. Carry this sense of calm with you throughout your day, reminding yourself that you possess the inner strength and tools necessary to manage your pain. Thank you for dedicating this precious time to yourself.

Namaste.

#affirmation #awareness #balance #blessed #chronicIllness #chronicPain #chronicPainManagement #chronicPainRelief #emotionalWellness #experience #fibromyalgia #flow #gratitude #healing #health #holistic #holisticHealth #illness #lupus #managingPain #meditation #mentalHealth #mentalWellbeing #mentalWellness #mindful #moments #ms #pain #practice #spoonie #visualization

pink lutos flowerwoman sitting on wooden plankswoman relaxing in yoga matlow angle photography gray sky
2025-12-06

Tierleid muss endlich beendet werden ✊ Das geht nur vegan.
Vegetarismus tötet Kälber und trennt Mütter von Kindern 🐄
Fleischkonsum sorgt für Tod und Leid der Tiere 🐄🐖🐔

Jeden Tag werden in Deutschland 2.000.000 Tiere getötet, Fische nicht mal inbegriffen. Damit muss Schluss sein!

Auch die Natur wird durch die Tierindustrie und ihren Flächenbedarf immer weiter zerstört.

Go vegan! Für Tier, Mensch und Umwelt. 🐄🐖🐔

Mit unserer Silent Line, Flyern und Gesprächen konnten wir viele erreichen nun vegan zu werden. 🫶

#weihnachten #veganeweihnachten #weihnachtenvegan #festderliebe #tierbefreiungstreff #tierleidfrei #gänsebraten #weihnachtsessen #tierhaltung #tierwohl #vegan #silentline #mahnwache #veganinmünster #münstervegan #münster #tierrechte #tierbefreiung #vegetarisch #veggie #käse #milch #weidemilch #biomilch #weide #ms

Aktivis stehen in der Innenstadt und halten Schilder mit Tieren darauf und Sprüchen wie "Kein Lammbraten" die Stadt ist sehr voll.Aktivis stehen in der Innenstadt und halten Schilder mit Tieren darauf und Sprüchen wie "Kein Lammbraten" die Stadt ist sehr voll.Aktivis stehen in der Innenstadt und halten Schilder mit Tieren darauf und Sprüchen wie "Kein Lammbraten" die Stadt ist sehr voll.Aktivis stehen in der Innenstadt und halten Schilder mit Tieren darauf und Sprüchen wie "Kein Lammbraten" die Stadt ist sehr voll.
2025-12-06

#SchindlersList #MS #ConcertMusic

“If you feel pain, you're alive. If you feel other people's pain, you're a human being.” - Leo Tolstoy

The woodwind player was diagnosed with MS and this was her last performance.

youtu.be/YqVRcFQagtI?si=Dl7nba

Gregory MSgregory_ms
2025-12-06

gregory-ms.com/articles/309181

Multiple Sclerosis is an inflammatory demyelinating disorder which affects the central nervous system. Treatment has traditionally focused on preventing inflammatory damage

2025-12-04

This is about #medicalcannabis in the UK, from the POV of the users, and how they get treated. More generally, we have been in need of #RationalDrugsPolicies for many years. 🙄

[The #WarOnDrugs has failed abysmally.]

Did you know #cannabis is about the ONLY remedy (that works!) for the #pain of #MS? 🤔 Other conditions too. Why are sufferers denied relief when it is so easily available? 🤔

thecanary.co/opinion/2025/12/0

𝕂𝚞𝚋𝚒𝚔ℙ𝚒𝚡𝚎𝚕kubikpixel@chaos.social
2025-12-04

»Microsoft — KI nicht so gefragt wie gedacht, Vertriebsquoten reduziert:
Microsoft hat wohl Probleme, seine mit großem Aufwand in nahezu alle Produkte des Softwaregiganten integrierten KI-Services zu vermarkten. […]«

Egal welche Hersteller, deren überhöten Gewinnwünsche sind nur absurd und deutet mMn auf die nächste finanziellen Absturz hin. Darunter leiden dann die Gekündigten und nicht die Firmen selbst.

🤖 winfuture.de/news,155358.html

#ki #microsoft #problem #vertrieb #ms #software #aufwand #it

lies_das :nona: Antifaschistlies_das@digitalcourage.social
2025-12-03

@markus_netzpolitik
Ja!
Es ist sowieso so
Aber das werde #ms #amazon #meta und andere verhindern
Die Rücknahme von Executive Order 14086 wird nicht stattfinden.
#usa #FailedStateUSA

2025-12-03

#Mastodon, #Fediverse, #help, please?

I have #MS, and I need to find #shoes with VERY VERY SOFT soles, even more than for diabetic neuropathy! Does anyone know of such shoes (thermally insulated too)?

I'd be REALLY grateful for your help here. A boost wouldn't go amiss either. Thanks! 🙏😃

[I live in the UK.]

Client Info

Server: https://mastodon.social
Version: 2025.07
Repository: https://github.com/cyevgeniy/lmst