Lmst

BoltzGen là mô hình AI đột phá, thiết kế protein và peptide (binder) để gắn kết đa dạng mục tiêu sinh học. Nó tích hợp thiết kế và dự đoán cấu trúc, đạt hiệu suất cao và được xác thực thực nghiệm, mở ra tiềm năng lớn cho y học và sinh học.

#BoltzGen #AI #ProteinDesign #DrugDiscovery #ThiếtKếThuốc #CôngNghệSinhHọc

https://www.reddit.com/r/singularity/comments/1p7npos/boltzgen_toward_universal_binder_design/

(31 Oct) Neural network finds an enzyme that can break down polyurethane https://s.faithcollapsing.com/b3v19 Archive: ia: https://s.faithcollapsing.com/sydso #ai #biochemistry #biology #chemistry #enzymes #neural-networks #polymers #polyurethane #protein-design #proteins #science

Image of a black and white athletic sneaker with an elaborate cushioning system in its heel.

Neural network finds an enzyme that can break down polyurethane https://arstechni.ca/pzjk #neuralnetworks #proteindesign #biochemistry #polyurethane #chemistry #polymers #proteins #Science #Biology #enzymes #AI

Our university established professorships in #Marketing & Technology and #AI-guided #ProteinDesign, supported by the Wübben Stiftung Wissenschaft. The professorships were appointed to David Finken and Thomas Schlichthärle (pictured): http://go.tum.de/670372

📷A.Eckert

💡 AI can predict protein structures — but can it predict how they behave?

🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.015

📚 CSBJ: https://www.csbj.org/

#AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.015

Do AI-designed proteins create a biosecurity vulnerability? https://arstechni.ca/8znR #riskassessment #proteindesign #bioterrorism #biohazards #security #Science #AI

Caltech doctoral student Vida Robertson highlighted a publication from Jens Meiler, from Vanderbilt University, who describes using Rosetta to design antibiotic peptides called lanthipeptides with antibiotic properties.

#SBGrid #NMR #ProteinDesign

NMR structure of a lanthipeptide produced by Enterococcus faecalis. Sulphur atoms show in yellow, forming interbackbone bridges. PBD 6VGT. CC by SBGRID

Since its release last year, the open-source platform BindCraft, developed by the Laboratory of Protein Design and Immunoengineering, has already disrupted the world of protein design.

Find out more: https://go.epfl.ch/b340be

#EPFL #ProteinDesign #AI

Latent Labs AI is democratizing protein design with a new web-based model! 🧬🔬 Making this tech accessible to all, not just experts.

Want to leverage AI for your projects? Softsasi offers custom AI solutions, data analytics, & more! Let's innovate together! 🚀 #ProteinDesign #AI #innovation

🤖 Can algorithms outsmart evolution to create therapies humans never imagined?

🔗 Computational nanobody design through deep generative modeling and epitope landscape profiling. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.052

📚 CSBJ: https://www.csbj.org/

#Nanobody #AI #DeepLearning #ProteinDesign #DrugDiscovery #ComputationalBiology #GenerativeAI #Immunotherapy #COVID19 #SARSCoV2 #Omicron #AntibodyEngineering #SyntheticBiology #TranslationalResearch

Computational nanobody design through deep generative modeling and epitope landscape profiling. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.052

NNF Center for Protein Design: a smart career choice for you?
https://youtube.com/shorts/hkPxqowK5KM?feature=share
#novonordiskfonden #novonordiskfoundataion #proteindesign #researchcenter #researchfunding #careeradvice #sciencecarers

Finally there will be a center for protein design in Denmark.

Since at least a few years, progress in these techniques has been at the very front of scientific endeavours within engineering biosciences and has resulted in a Nobel prize to some of the most important contributors:

https://www.nobelprize.org/prizes/chemistry/2024/popular-information/

Novo Nordisk Foundation provides funding for research center (article in Danish)
https://novonordiskfonden.dk/nyheder/nyt-dansk-forskningscenter-skal-skabe-designede-proteiner-med-kaempe-potentiale/

#proteindesign
#structuralbiology

🧬 Protein engineering breakthrough! Scientists hack SSB protein's condensation properties by tweaking its linker region. Precision meets molecular magic! 🔬 #Genomics #ProteinDesign #ScienceInnovation https://emmecola.github.io/genomics-daily

Scientists built a protein that moves like nature intended—unlocking a new era for medicine, AI, and self-healing materials. #ProteinDesign #SyntheticBiology #AIinScience

https://geekoo.news/proteins-that-morph-heal-and-transform/

Will protein design tools solve the snake antivenom shortage?

https://www.owlposting.com/p/will-protein-design-tools-solve-the

#HackerNews #proteinDesign #snakeAntivenom #healthcare #innovation #biotechnology

🚀 What role does protein design play in advancing next-gen optogenetic tools?

🔗 Protein design accelerates the development and application of optogenetic tools. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.014

📚 CSBJ: https://www.csbj.org/

#Optogenetics #ProteinEngineering #Neuroscience #AlphaFold #ProteinDesign #SyntheticBiology

Protein design accelerates the development and application of optogenetic tools. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.014

Job - Alert 🌱

‼️ POSTDOCTORAL SCIENTIST (M/F/D)

Deadline: 2025-04-06
Location: Germany, Regensburg, Bayern

https://www.academiceurope.com/job/?id=7176

#hiring #Immunotherapy #Postdoc #LIT #syntheticbiology #proteindesign

PhD Student Position: Drug Development for Parkinson's Disease

Ben-Gurion University of the Negev

#PhDStudentPosition: #DrugDevelopment for #Parkinson'sDisease using #ProteinDesign, #ComputerAidedDrugDesign, #GeneTherapy, #iPSCs

See the full job description on jobRxiv: https://jobrxiv.org/job/ben-gurion-university-of-the-negev-27778-phd-student-posit...
https://jobrxiv.org/job/ben-gurion-university-of-the-negev-27778-phd-student-position-drug-development-for-parkinsons-disease/?feed_id=92530

PhD Student Position: Drug Development for Parkinson's Disease

Ben-Gurion University of the Negev

#PhDStudentPosition: #DrugDevelopment for #Parkinson'sDisease using #ProteinDesign, #ComputerAidedDrugDesign, #GeneTherapy, #iPSCs

See the full job description on jobRxiv: https://jobrxiv.org/job/ben-gurion-university-of-the-negev-27778-phd-student-posit...
https://jobrxiv.org/job/ben-gurion-university-of-the-negev-27778-phd-student-position-drug-development-for-parkinsons-disease/?feed_id=92033

https://youtube.com/watch?v=P_fHJIYENdI&si=ECF7pagdnAgEwT4Z

Veritasium just released a great video of #ProteinFolding algorithms and #AlphaFold as part of the story.

The Veritasium team releases some of the best science videos around: accessible, clear and accurate. It's a great service to communicate this breakthrough to everyone.

#ScientificComputing #Bioinformatics #AI #MachineLearning #ScienceCommunication #ProteinDesign

P.S. shame about the anthropomorphic hype at the end

#ProteinDesign

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