#Denitrification in tiny #anoxic pock­ets on #sand grains could ac­count for 1/3 of total #nitrogen loss in silic­ate shelf sands.

mpi-bremen.de/en/Nitrogen-...

Our newly developed #microfluidic method revealed #microorganisms on sand grains create anoxic microenvironments allowing #denitrification in well-oxygenated sands

Out now in Scientific Reports
@natureportfolio

doi.org/10.1038/s415...

SciTech Chronicles. . . . . .May 16th, 2025

https://bit.ly/stc051625

#iCares #microfluidic #biomarker #prediction #amber #deformation #"fluorescence imaging" #flame-shaped #MSR #Thorium #modular #cartridge #scalable #recyclable #degradability #durability #cis-urocanic #urocanase #microbiome #"UV radiation"

Portable tests deliver #plant #disease results in under 30 minutes

#LyoBead #LAMP #pathology #primers #Phytophthora #Microfluidic #agriculture

https://phys.org/news/2025-02-portable-disease-results-minutes.html

Engineers develop #microfluidic protocol to extract and purify #DNA

#lab_on_chip

https://phys.org/news/2025-01-microfluidic-protocol-purify-dna.html

#PRNTDpump: #OpenSource nonelectric spring-driven #syringe #pump with #3Dprinted components for #microfluidic applications:

-no external power requirement (off-grid usage)
-fabrication cost: $25-30

https://doi.org/10.1016/j.ohx.2024.e00550
#DIYbio #lab #instruments #microfluidics #FrugalScience

#OpenSource #strobe-enhanced #microscopy stage:

-workstation for sharp #imaging of fast processes
-developed for #microfluidic #droplet generation
-#PiCam lens: FoV ~1mm
-#LED strobe #illumination

Web: https://wenzel-lab.github.io/strobe-enhanced-microscopy-stage/
#DIYbio #lab #instruments #microscope #microfluidics

#MOS3S: #Microfluidic-assisted #OpenSource #3Dbioprinting system for the engineering of hierarchical #tissues:

-#3dprinted parts
-#syringe #pumps
-fabrication of cm scale lattice constructs

https://doi.org/10.1016/j.ohx.2024.e00527
#DIYbio #lab #instruments #hydrogel #bioprinter #tissue

In this project, we screened de novo designed protein libraries without natural ancestry for function, using #microfluidic droplets - and massively enriched short, truncated protein fragments. Turns out that these ≈ 40- to 60-residue fragments oligomerize to form a dynamic, catalytically proficient assembly, just as primordial peptides might have formed early enzymes during the prebiotic events that led to the #OriginOfLife! #ProteinEvolution

New #single_cell analysis tech incorporates advanced fiber optics directly into #microfluidic chips.

#OptiDrop

https://phys.org/news/2024-04-cell-analysis-tech-incorporates-advanced.html

Improving #plant health diagnostics: The dawn of #microfluidic devices for rapid #miRNA detection.

#miR399 #phosphate #nutrition

https://phys.org/news/2024-03-health-diagnostics-dawn-microfluidic-devices.html

The design and fabrication of customized #microwells and #microfluidic chips is often challenging. This #PLOSBiology study describes a pipeline for resin-based 3D printed constructs and provides a variety of applications in biological #experiments.

https://plos.io/3TENGHq

#KATARA: #OpenSource controller (~$200) for #microfluidic large-scale integration:

-up to 70 #solenoid valves
-#Arduino-/#Python-/#GUI-control

https://doi.org/10.1016/j.ohx.2017.10.002
#DIYbio #lab #instruments #microfluidics

#micrIO: A #Python-controlled #OpenSource #autosampler & #FractionCollector for #automated #microfluidic input-output:
https://doi.org/10.1039%2Fc9lc00512a
#DIYbio #lab #instruments #automation #microfluidics #fluidics

#Microfluidic environments alter #microbe #behaviors, opening potential for engineering their social #evolution.

https://phys.org/news/2024-02-microfluidic-environments-microbe-behaviors-potential.html

#OpenSource, programmable pneumatic setup for operation & #automated control of single- & multi-layer #microfluidic devices:

-#Python #pneumatic control software (#Geppetto), #Kivy #GUI & optional Windows binary

https://doi.org/10.1016/j.ohx.2017.10.001
#DIYbio #lab #instruments #microfluidics

#Microfluidic chip reveals that #bacteria swim toward large, complex #polymers.

#chemotaxis #sensing #polysaccharides #DMSP

https://phys.org/news/2024-02-microfluidic-chip-reveals-bacteria-large.html

#FOMSy: #3Dprinted flexible #OpenSource #microfluidic system & flow synthesis of #PET-tracer:
https://doi.org/10.1007/s41981-023-00267-z
#DIYbio #chemistry #lab #instruments #microfluidics #radiochemistry #FlowChemistry #fluorination

A study conducted at the CiTOS Lab potentially reshapes the preparation of high-value compounds in organic chemistry. This innovative approach combines Quantum Chemistry and #Artificial #intelligence enabling the generation of optimized process conditions within minutes, completely waste-free. The project establishes a robust foundation for a radical shift in the approach to preparing high-value organic compounds.
#chemistry #AI #QuantumChemistry #Microfluidic #CiTOS

https://www.molsys.uliege.be/cms/c_12284394/en/a-new-paradigm-for-reaction-optimization-in-organic-chemistry

Low-cost #OpenSource inertial #microfluidic device for #microparticle separation: A #laser-ablated #PMMA lab-on-a-chip approach without a #cleanroom:
https://doi.org/10.1016/j.ohx.2023.e00493
#DIYbio #lab #instruments #microfluidics #chitosan #LoC #COMSOL

new citation:

`Using salt tolerance compartmentalized self-replication (stCSR) and a #microfluidic platform, we obtained 11 mutant sites with enhanced salt tolerance attributes. #Sequencing and #biochemical analyses revealed that the substitution of conserved amino acids such as G197D, Y369E, T372N, and I378R plays a critical role in maintaining the #processivity of exonuclease-deficient #phi29 #polymerase under high salt conditions.`

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1267196/full

#nanopore #DNA #singleMolecule