A mouse study found that lactate, whether produced by exercise or administered exogenously, reduces cognitive impairment. This provides a potential explanation for the effects of exercise in mitigating the effects of Alzheimer's disease.
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-04168-x
https://direct.mit.edu/imag/article/doi/10.1162/imag_a_00452/127397/Functional-magnetic-resonance-spectroscopy-of nice fMRS paper measuring lactate in the motor cortex at 3T! #fMRS #lactate
New findings: more evidence of poor oxygen perfusion in the brain
https://youtu.be/g4hLI5ktOhE?si=6vbxMnDAGKCfUNsd
"We seeing high levels of lactate and low levels of choline in the brains of Gulf War Illness sufferers. This quick update covers our new analyses and why the may be important to those with chronic pain, fatigue, and cognitive issues. - Jarred Younger"
#GulfWarIllness #ChronicIllness #ChronicPain #choline #lactate
#BrainPerfusion
#MECFS
Instead of a blood stick use your sweat! Washington State University bioengineers have successfully 3D printed a flexible patch with multiple micro channels for colorimetric bioassays for up to 3 biomarkers. #sweat #glucose #uricacid #lactate #diabetes #gout #exercise
https://www.instagram.com/p/C8qsViRRAge/
Re-interpreting the rise in blood lactate during exercise: lactate is ordinarily produced after eating carbohydrate, and is preferred to glucose as a fuel for some muscles.
https://scitechdaily.com/new-research-debunks-common-belief-that-high-lactate-levels-are-bad/
Brain Acidity Linked With Multiple Neurological Disorders
https://www.sciencealert.com/brain-acidity-linked-with-multiple-neurological-disorders #psychology #BrainAcidity #Neurological #Disorders #metabolic #dysfunction #lactate #pH
@matdesgro I mean we all agree that lactate guided resuscitation is a dumb strategy. In RCT comparing #lactate guided vs #CRT guided, no difference was found. Then, CRT guided resuscitation is a dumb strategy
Just as any strategy based on the correction of clinical signs of #shock (#tachycardia, #hypotension, encephalopathy, #oliguria, crt, #molting, cutaneous temperature or lactate). This are signs of a syndrome, none of them is nor sensitive nor specific alone.
Many people think that #Sweat is just #Water and #Salt
Not true
Apart from #Sodium and #Chloride,#Sweat includes ions as #Potassium,#Calcium and #Magnesium as well as traces of metabolites:#Lactate,#Ammonia, and #Urea
If u wear clothes that are very tight to body, sweat would not cool your body but permeates the clothes, or remains on your skin, Skin is like another ecosystem: filled with #Macrobiota:#Fungi, #Bacteria and #Viruses -some are not friendly- There may be parasites: acari for example
After plenty of nurturing, my #preprint baby has now matured into a fully formed publication in Aging. https://doi.org/10.18632/aging.204565 This #Drosophila study on #lactate #brainmetabolism, #Aging and #Memory is my first paper including data from my PhD thesis. I’ve got a couple more papers up my sleeve before I graduate this summer. Keeping my eyes out for #postdoc positions studying aging and behaviour in flies.
The brain's ability to use lactate, a byproduct of sugar metabolism, to support neuronal signaling and memory formation traces back to genes that evolved well before the emergence of higher cognitive functions. https://phys.org/news/2023-02-memory-brain.html
#brain #memory #lactate #signalling
I'm pretty happy with today's #bike ride, even the part about an hour in where I tried to do a #lactate threshold interval and wound up with a quad pump instead about six minutes in. I might want to revisit that, though it's hard to find routes with multiple miles with no stoplights.
I also want to spring for pedal power meters to test my suspicion that the #Strava power estimate is low by about a factor of two.
