Lmst

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Always cool seeing big general science YouTube channels cover our chronic illnesses.

Perhaps sad that them just calling the scale of the problem right is a thrill...

But Anton Petrov actually informed me on NETs -> microclots, from a #TeamClots study, earlier this year.

Description by Gemini Fast: A screenshot from a video titled "Bizarre Structures Inside Blood May Be Responsible for Long COVID." A man with short dark hair, wearing a blue t-shirt, is speaking, positioned in front of a massive, 3D visualization of a blue and orange spiky molecular structure (likely the SARS-CoV-2 virus).

Description by Gemini Fast: A false-color, fluorescence micrograph of a microscopic structure, likely a Long COVID microclot. The structure glows red, green, and cyan against a black background and is labeled with arrows pointing to its components: ThT (Thioflavin T, indicating amyloid structures), MPO (Myeloperoxidase), and DNA, suggesting a complex of Neutrophil Extracellular Traps (NETs).

Description by Gemini Fast: A screenshot showing the title page of a research article from the Journal of Medical Virology. The title reads: "Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients." The names of the researchers and their international affiliations are listed below.

Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients

https://onlinelibrary.wiley.com/doi/10.1002/jmv.70613

Screenshot from latest Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
#auscovid19
#TeamClots #PASC

Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients — Alain R. Thierry et al.
"The plasma concentrations of circulating DNA, [myeloperoxidase] and [neutrophil elastase] are statistically much higher in patients with LC than in healthy patients (5.7‐, 3.5‐ and 14.9‐fold)."

Nailfold Capillaroscopy:  Unveiling Fibrinoid Microclots and Microcirculation Dynamics
https://www.buzzsprout.com/2405788/episodes/17522448
https://helioxpodcast.substack.com/publish/post/168582768

July 21, 2025 • (S5 E3) • 17:20
Heliox: Where Evidence Meets Empathy 🇨🇦‬

Researchers are now developing smartphone apps that can do preliminary assessments of microcirculation using your phone's camera with a simple lens attachment.

Machine learning systems are already being trained to analyze these images with superhuman accuracy.

Flow Cytometric Detection of Fibrin(ogen) Amyloid Microclots”  https://www.buzzsprout.com/2405788/episodes/17447130

On the Utility of Nailfold Capillaroscopy in Detecting the Effects of Fibrinoid Microclots in Diseases Involving Blood Stasis  https://www.buzzsprout.com/2405788/episodes/%20https://www.preprints.org/manuscript/202505.2356/v1

#MedicalResearch #ChronicIllness #BloodClots #LongCOVID #HealthScience #Microcirculation #TraditionalMedicine #AI #Diagnostics #Capillaroscopy #microclots #S1 #AmyloidProtein #TissueHypoxia #Covid19 #TeamClots

Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry

https://www.medrxiv.org/content/10.1101/2024.05.17.24307553v3?ct=

"our findings indicate that thromboembolic pathways may contribute to #longCOVID independently of acute disease severity"

#TeamClots @longcovid
#PwLC #PostCovidSyndrome #LC #PASC #postcovid #CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver #auscovid19

my lovely friend 🐾@angryhacademic now also has an fb page dedicated to

#longcovid #postvac #MECFS #POTS #MCAS #teamclots #chronicillness #CovidIsntOver
🖖🏾

https://www.facebook.com/profile.php?id=61564460637317

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"in the rat models, the concentration of microthrombus is reduced by more than 60% in 3 minutes"

Hashtags:
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver #auscovid19 @auscovid19 #TeamClots

Interventional Removal of Travelling Microthrombi Using Targeted Magnetic Microbubble

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202401631

"In this work, an interventional method is developed to identify & remove the traveling microthrombi using targeted-magnetic microbubbles (TMMBs) & an interventional magnetic catheter”

@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 #TeamClots
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"Our study revealed that NETs may be a component of circulating FAM, suggesting that higher NETs formation promotes the stabilization of FAM in the circulation, leading to deleterious effects which (in part) may contribute to the symptoms of LC."

Hashtags:
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
#LongCovid #TeamClots

New pre-print:
Circulating microclots are structurally associated with Neutrophil Extracellular Traps and their amounts are strongly elevated in long COVID patients

https://www.researchsquare.com/article/rs-4666650/v1

====
Hashtags:
@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid #CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver #auscovid19 @auscovid19
#TeamClots

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New pre-print:

Flow Clotometry: Measuring Amyloid Microclots in ME/CFS, Long COVID, and Healthy Samples with Imaging Flow Cytometry

https://www.researchsquare.com/article/rs-4507472/v1

Hashtags:
@longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC #COVIDBrain
#TeamClots @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @covid19

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Microclot concentrations determined by the present cell-free flow clotometry technique for the three cohorts

from

Flow Clotometry: Measuring Amyloid Microclots in #MECFS, #LongCOVID, & Healthy Samples with Imaging Flow Cytometry

https://www.researchsquare.com/article/rs-4507472/v1
#TeamClots #CFS #PwME @longcovid @mecfs @covid19

Microclot concentrations determined by the present cell-free flow clotometry technique for the three
cohorts. P-values and significance reported.

🧵
New pre-print:

Flow Clotometry: Measuring Amyloid Microclots in ME/CFS, Long COVID, and Healthy Samples with Imaging Flow Cytometry

https://www.researchsquare.com/article/rs-4507472/v1

=========
@longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC #COVIDBrain
#TeamClots #MEcfs #CFS #PwME @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

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Screenshot of (i) Expanded Key Points for Review Only & (ii) Main Key Points

Should those affected run for public office?

If COVID-19 typically causes cognitive decline, increased aggression, and reduced risk aversion, should those affected run for public office? Microclot testing, a valid indicator of past COVID-19 infection, might explain its unavailability in Canada.

#Teamclots #MicroClotTesting #PublicOffice

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A detailed article giving varying perspectives of scientists on the validity of the hypotheses, and the need for clinical trials of treatments currently being sold to patients.

Hashtags:

@longcovid
#LongCovid #PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #auscovid19 @auscovid19

#CovidLong #PostCovid19 #TeamClots

Increased fibrinaloid microclot counts in platelet-poor plasma are associated with #LongCOVID

https://t.ly/7bSYH

Replication study of microclots by a UK team using an automated quantification method and refining sampling handling to reduce the potential for processing artifacts

#TeamClots @longcovid
#PwLC #PostCovidSyndrome #LC #PASC #postcovid
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #CovidBrain @auscovid19

Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID

Free full text:
https://www.mdpi.com/2075-4426/14/2/170

#teamclots @longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #PASC

@covid19 #Coronavirus
#COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #COVIDBrain
@auscovid19

Newly announced upcoming clinical trial:

"A clinical trial to test if the fibrinolytic enzyme Lumbrokinase improves symptoms and mitigates blood clotting issues or platelet hyperactivation in patients with #LongCOVID, ME/CFS, & LongLyme disease."

https://polybio.org/projects/lumbrokinase-longcovid-me-cfs-clinical-trial/

@mecfs

#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #TeamClots @longcovid
#PwLC #postcovid #postcovid19 #LC #PostCovidSyndrome #longhaulers #PASC
@covid19 #Coronavirus
#COVID19 #COVID #SARSCoV2

Good news! My microclots are no longer severe! I’m in the safe zone after 8 months of TT then DT 🎉

Thanks much to #TeamClots for confirming suspicions many of us had + my Long Covid microclot doctor for the assist! Hope it stays this way as long as possible

June 2023 versus February 2024
#MECFS #LongCovid