@tiktokapotheek Check apotheek.nl
🔗 Meer info over eczeem, zalven of crèmes? eczeemwijzer.nl

🤍 Samen maken we de apotheek zichtbaar op social media.
Deel & steun!
#TikTokApotheek #smeren #vingertopeenheid #VTE #apotheek #medicijnvragen #eczeem #huid #zalf #creme

TIL: On peut faire des liens avec des ancres dans un terminal (l'équivalent de la balise HTML `<a>`) 🤯

Je suis tombé là-dessus en regardant la sortie de la commande `hostnamectl` qui faisait pointer le texte `Ubuntu 24.10` vers le site d'Ubuntu…

J'avoue que je ne sais pas trop quoi en pense mais si jamais vous êtes curieux, la spec est par là 😅 :

➡️ https://gist.github.com/egmontkob/eb114294efbcd5adb1944c9f3cb5feda

#Linux #VTE #Terminal #OSC

2️⃣ Adriani highlights a study that explores targeting Factor XI to prevent dangerous clots like DVT and pulmonary embolism—avoiding the bleeding risks of current treatments. #preprint from the Yamashita Lab.

#preLight: https://prelights.biologists.com/highlights/factor-xi-localization-in-human-deep-venous-thrombus-and-function-of-activated-factor-xi-on-venous-thrombus-formation-and-hemostasis-in-rabbit/

#biochemistry #medicine #coagulation #hemostasis #pathology #VTE

Also, by the way, this paper contains the history of #VTE that I often use in my talks. (Updated to include not just the technological breakthroughs in experimental techniques and the mathematical sciences, but also the theoretical breakthroughs that were necessary to get us to see rats "thinking about the future".)

I think this speaks to why science is slow and why we have to look at science over a long time scale

#neuroscience #science #SlowScience

@dimokaramanlis @elduvelle_neuro @jessetm

It is important to distinguish the computations going on within the subject.

Technically, #VTE is a behavior of pausing attentively, orienting and re-orienting (as originally defined by Gentry, Muenzinger, and Tolman in the 1930s). But what we really care about are the neurophysiological computations that behavior is reflecting at the moment.
(We want to take the subject's POV, not the experimenter's.)

There are currently (to my knowledge) two computations that have been shown to create attentive pause and reorientation behaviors (i.e. VTE).

(1) Sensory discrimination --- the subject is turning to focus sensory signals on sensory receptors.

(2) Planning systems --- the subject pauses to send hippocampal sweeps down the two options. What causes the reorientation is unknown, but I suspect that it is action chains that are halted.

Both the timing of each of these (in what situations they appear) and the neural circuits involved in each are different.

See the paper @elduvelle cites (https://www.nature.com/articles/nrn.2015.30) for a review, including a discussion of this issue. A good example of the distinction is in Bett et al (https://www.frontiersin.org/journals/behavioral-neuroscience/articles/10.3389/fnbeh.2012.00070/full).

PS. Yes, mice and rats both definitely do VTE. Primates do a thing called SFS (saccade-fixate-saccade), which appears similar (likely with two meanings, much like rodents).

For our next #NeuroESC #JournalClub I will read this paper from @jessetm :

Flexible decision-making is related to strategy learning, vicarious trial and error, and medial prefrontal rhythms during spatial set-shifting

get the PDF at: https://drive.google.com/file/d/1qmfyeNkOwe_R-tvCOc0uSq3AX2WkMt4I/view?usp=sharing

Anyone else interested? We could all pledge to read it and then discuss it here afterwards (Next Friday) 👀

#Neuroscience #VTE #FlexibleDecisions #SpatialCognition #mPFC #NavigationStrategies

#VTE detection: what's the best algorithm out there to detect Rat VTEs from 2D head position data (no HD data)?
By "best" I mean least effortful for the user...

I know that @adredish has the D-phil method (explained in Interactions between deliberation and delay-discounting in rats #RedishLab which is used quite a lot.

But also just found out about a different method from @jessetm explained in A Machine Learning Approach for Detecting Vicarious Trial and Error Behaviors #MizumoriLab - Jesse, I haven't checked the details yet but as its creator, would you recommend it? Would you have code for it somewhere? I couldn't see a repo link in the paper but maybe I missed it. 🙏

Edit: Jeff Stott added this one to the list, which uses a "Curvature" measure (also from #RedishLab): A functional difference in information processing between orbitofrontal cortex and ventral striatum during decision-making behaviour

Any other ones out there?
#Neuroscience #NeuroMethods #SpatialCognition

The following hashtags are trending across South African Mastodon instances:

#politics
#poll
#polls
#tshwane
#water
#worldthrombosisday
#thrombosisawareness
#VTE
#bloodclots
#patientempowerment

Based on recent posts made by non-automated accounts. Posts with more boosts, favourites, and replies are weighted higher.

The following hashtags are trending across South African Mastodon instances:

#politics
#poll
#polls
#worldthrombosisday
#thrombosisawareness
#VTE
#bloodclots
#patientempowerment
#healthcareprofessionals
#preventthrombosis

Based on recent posts made by non-automated accounts. Posts with more boosts, favourites, and replies are weighted higher.

The following hashtags are trending across South African Mastodon instances:

#politics
#poll
#polls
#Wordle
#wordle1212
#fediverse
#worldthrombosisday
#thrombosisawareness
#VTE
#bloodclots

Based on recent posts made by non-automated accounts. Posts with more boosts, favourites, and replies are weighted higher.

🌍 𝗧𝗼𝗱𝗮𝘆 𝗶𝘀 𝗪𝗼𝗿𝗹𝗱 𝗧𝗵𝗿𝗼𝗺𝗯𝗼𝘀𝗶𝘀 𝗗𝗮𝘆!

Let's raise awareness about thrombosis and its impact on global health. Did you know that 1 in 4 people die from conditions caused by thrombosis?

🩸 It's crucial to understand the risks and take action. Healthcare professionals and patients alike can make a difference by being informed and proactive.

💡Remember, knowledge is power! Together, we can reduce the burden of thrombotic events.

𝗝𝗼𝗶𝗻 𝘁𝗵𝗲 𝗰𝗼𝗻𝘃𝗲𝗿𝘀𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝗵𝗲𝗹𝗽 𝘀𝗽𝗿𝗲𝗮𝗱 𝘁𝗵𝗲 𝘄𝗼𝗿𝗱!

#WorldThrombosisDay #ThrombosisAwareness #VTE #BloodClots #PatientEmpowerment #HealthcareProfessionals #PreventThrombosis #KnowTheRisks #StayInformed #SCABPharmacy

.: :terminal: Sakura Terminal :terminal: :.

Is a terminal emulator based on GTK+ and VTE. It's a terminal emulator with few dependencies, so you don't need a full GNOME desktop installed to have a decent terminal emulator.

Being trying and I like it a lot.

https://www.mankier.com/1/sakura

Surely I replace it for Xterm...

I like Xterm also, but Sakura is more powerful.

Cheers!

#sakura #terminal #linux #VTE #gtk

I released the new version of one of my oldest projects!

🐸 **kermit**: A froggy terminal emulator.

🐸 Not written in Rust - don't *frog* out.

🎨 Supports tabs and customization.

⭐ GitHub: https://github.com/orhun/kermit

#terminal #emulator #opensource #release #project #linux #vte

@Andrewpapale @elduvelle_neuro @BrianMSweis

Sweeps are theta sequences. 100% They do tend to go farther during VTE than during normal running, but they are definitely relatively normal theta sequences.

As you may know, there is this paper by Papale et al (2016 Neuron 😉​​) that definitively showed that animals are in theta through VTE. This can also be seen in the original Johnson and Redish 2007 JNeurosci paper as well as in the Kay et al 2020 Cell paper, and all the other ones that have looked.

What is more controversial is whether #VTE = #Deliberation. My view is that VTE is a subset of Deliberation. You can see Deliberation without VTE, but not VTE without Deliberation.

In general, what we see is three stages of theta sequences.

(1) When an animal knows the maze, but not what to do on it, you see alternating sweeps to the goal in theta and commonly VTE (although sometimes just pausing or slowing through the choice point). [Deliberation]

(2) When an animal knows the maze and what to do, but is still in "hippocampal" mode, you see sweeps to one side (the next goal). [Planning/Checking]

(3) When an animal has automated what to do, sweeps drop down to very small (not going all the way to the goal), and task bracketing shows up in dorsal striatum. [Habit/Automation]

See Redish 2016 Nature Reviews Neuroscience for a thorough review. This story has been confirmed by many papers since. Most recently see Ugurcan Mugan's 2024 bioRxiv paper.

@elduvelle_neuro

Mice definitely do #VTE (Vicarious Trial and Error) behaviors. We've seen them in our Restaurant Row task. (Take a look at the various @BrianMSweis papers. They VTE in the offer zone as they learn to precommit to avoid the sunk costs.)

Primates do as well, but in primates they are generally saccade-fixate-saccade sequences rather than actual head movements.

#DecisionMaking #SpatialCognition

Найкращий, легкий та простий емулятор терміналу.

Sakura - це емулятор термінала, і його єдиними залежностями є GTK та VTE. Він використовує блокнот, щоб забезпечити кілька терміналів в одному вікні й дозволяє змінювати параметри конфігурації через контекстне меню. Не більше і не менше.

#terminal #emulator #gtk #vte #linux #gpl #gpl2 #foss

Very nice example of real-life, human #VTE
(vicarious-trial-and-error)
@adredish

Source: Friends

@edeno cool thanks! Putting some screenshots for illustration.. it definitely seems like a lot of events happen at the choice point, but strangely, most if not all of the replay examples shown in the paper are from the reward locations.

Also, as you say, it is not clear that those events were during SWRs and not theta - the theta/delta ratio around “replays” does seem quite similar to the rest of behaviour... it would have been nice if they had made this figure separately for reward vs choice point events. Actually they even say that their choice point events could be similar to @adredish ‘s #VTE activity, which is definitely #ThetaSequences. 🤔

(For reference, here is the paper:
Awake replay of remote experiences in the hippocampus)

FLAME Study, too good to be true? #VTE #PE #thrombectomy https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.123.013406

@eRatt Ahaha I think this is a documented behaviour in the rat scientific literature called “Vicarious Trial-and-Error” (#VTE) - they do this a lot at choice points in mazes! But it’s supposed to be helping them know where to go next, not figure out where they currently are… super interesting to see it in a “natural” setting!
It would be so cool to see a video if you ever did it again! 👀