"Post Covid Syndrome and Cognitive Dysfunction – Aetiology and Possible Treatment" - I think figure 1, the arrows going towards "cognitive dysfunction" should be bidirectional - but otherwise, yet another lay of the land paper implicitly but strongly suggesting that there is a pressing need for research focus on LC and ME/CFS treatments: https://cdn.fortunejournals.com/articles/post-covid-syndrome-and-cognitive-dysfunction-ndash-aetiology.pdf

#CovidIsNotOver #LongCOVID #SARSCoV2 #CovidCompetent #AirborneAware #LC #CD #CognitiveDysfunction #PCS #COVID #COVID19

Marveling the Mysteries of Memory: How Our Brain Reactivates and Perceives Sensory Experiences

#MemoryMagic #SensoryPerception #Neuroscience #Hippocampus #CognitiveFunction #Neuroplasticity #OlfactorySenses #PTSD #EmotionalHealth #BrainScience #CognitiveDysfunction #MindAndBody #Neurotransmission #MemoryReactivation #MentalHealthMatters

https://youtube.com/shorts/1BQGQkJ1LwY?feature=share

From HQ

Joe reminding us #trump's brain is fried.
FRIED.
FRIED.

#CognitiveDysfunction #dementia #dementeddonnie

Type I interferon signalling, cognition and neurodegeneration following COVID-19: update on a mechanistic pathogenetic model with implications for Alzheimer’s disease.

Selective vulnerability of neurogenesis sites to IFN-I dysregulation would then lead to clinical manifestations such as anosmia and cognitive impairment.

#Neurodegeneration #CognitiveDysfunction #IFNI

https://www.frontiersin.org/articles/10.3389/fnhum.2024.1352118/full

#TheMetalDogArticleList
#BLABBERMOUTH
MICK MARS Refused To Believe He Would Be Confined To A Wheelchair
In a new interview with Jacqui Neal, MÖTLEY CRÜE guitarist Mick Mars spoke about his ongoing battle with degenerative disease ankylosing spondylitis (AS).

https://blabbermouth.net/news/mick-mars-refused-to-believe-he-would-be-confined-to-a-wheelchair

#MickMars #AnkylosingSpondylitis #MotleyCrue #DebilitatingDisease #FightingPain #TouringChallenges #SoloAlbum #ResidencyPossibility #HealthConcerns #Lawsuit #BandConflict #CognitiveDysfunction

#LongCovid
##CognitiveDysfunction
"Such long-term issues were collectively referred to as “long Covid” and were reported to affect nearly every organ system.1 The cardinal features of long Covid include fatigue, dysautonomia (or postural orthostatic tachycardia syndrome), postexertional malaise, and cognitive difficulties that are colloquially referred to as “brain fog.”"
https://www.nejm.org/doi/full/10.1056/NEJMe2400189

#LongCovid mechanisms
#CognitiveDysfunction

"Long COVID has remained an on-going public health issue in the years following the global pandemic. Here, we report blood–brain barrier disruption in patients with acute SARS-CoV-2 infection and brain fog, and patients presenting with long COVID, brain fog and cognitive decline, compared to those with long COVID without any neurological symptoms."

https://www.nature.com/articles/s41593-024-01577-8

#LongCovid mechanisms
#CognitiveDysfunction

"Here we show that BBB disruption is evident during acute infection and in patients with long COVID with cognitive impairment, commonly referred to as brain fog. Using dynamic contrast-enhanced magnetic resonance imaging, we show BBB disruption in patients with long COVID-associated brain fog"

https://www.nature.com/articles/s41593-024-01576-9

https://www.sciencedirect.com/science/article/abs/pii/S0898656823002553

The role of #PERK-#eIF2α-#ATF4-#CHOP #pathway in #sevoflurane induced #neuroapoptosis and #cognitivedysfunction in aged mice

10.1016/j.cellsig.2023.110841

#POCD #hippocampus #apoptosis #endoplasmicreticulum #volatileanesthesia #inhalationanesthesia #anesthesia #fluorinatedethers #alzheimers

@Javier_DN Is it true that in societies where big families -sometimes 4 generations- live together, Alzheimers disease is less prevalent?
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer
#CognitiveDecline #CognitiveDysfunction #Dementia #Hippocampus #Neuroimaging #NeuroImage #SocialIsolation #SocialBond
#Biomedicine #Health

Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study

Social isolation contributes to human brain atrophy and cognitive decline, indicating an opportunity to reduce dementia risk by promoting social networks.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer
#CognitiveDecline #CognitiveDysfunction #Dementia #Hippocampus #Neuroimaging #NeuroImage #SocialIsolation #SocialBond
#Biomedicine #Health

https://elifesciences.org/articles/83660

Social Bonds Protect Aging Brains

Social isolation can potentially harm brain structure and cognitive performance, suggesting an increased risk of conditions like Alzheimer’s dementia.
A lack of quality social interaction can lead to a decrease in the hippocampus’s volume, crucial for memory formation and retrieval, and poorer cognitive performance.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer
#CognitiveDecline #CognitiveDysfunction #Dementia #Hippocampus #Neuroimaging #NeuroImage #SocialIsolation #SocialBond
#Biomedicine #Health

https://neurosciencenews.com/social-aging-neuroscience-brain-23505/

Running throughout Middle-Age Keeps Old Adult-Born Neurons Wired

Long-term running maintains the wiring of “old” new neurons, born during early adulthood, within a network that is important for memory function during aging in mice.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neurogenesis #Neuron #BrainAging #Aging #MemoryLoss #CognitiveDecline #CognitiveDysfunction #PhysicalActivity #PhysicalExercise #Running

https://www.eneuro.org/content/10/5/ENEURO.0084-23.2023

Running Rewires the Aging Brain: Exercise Protects Memory Function

Physical activity, particularly running, has been found to rewire aging brains, helping to preserve memory functions.
Long-term running keeps older neurons wired, potentially preventing age-related memory loss and neurodegeneration.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neurogenesis #Neuron #BrainAging #Aging #MemoryLoss #CognitiveDecline #CognitiveDysfunction #PhysicalActivity #PhysicalExercise #Running

https://neurosciencenews.com/running-neurogenesis-aging-23339/

Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer’s disease brains

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #CognitiveDecline #CognitiveDysfunction #MemoryLoss #BetaAmyloid #AmyloidFibrils #Aβ #AβFibrils #Immunotherapy #Lecanemab

https://www.cell.com/neuron/fulltext/S0896-6273(23)00269-6

Alzheimer’s Drug Lecanemab Shields Brain from Free-Roaming Amyloid Fibrils

Amyloid beta protein forms small aggregates that disrupt brain function in Alzheimer’s disease.
Lecanemab, a recently FDA-approved Alzheimer’s treatment, can neutralize these disruptive aggregates, hinting at its potential to slow down the disease’s cognitive decline.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #CognitiveDecline #CognitiveDysfunction #MemoryLoss #BetaAmyloid #AmyloidFibrils #Immunotherapy #Lecanemab

https://neurosciencenews.com/amyloid-fibril-neuropharmacology-23207/

Imaging Study Implicates Reactive Astrocyte-Neuron Interaction in Alzheimer’s Cognitive Decline

PET imaging with 11C-acetate and 18F-FDG was used to visualize the reactive astrocyte-induced acetate hypermetabolism and associated neuronal glucose hypometabolism in brains with neuroinflammation and Alzheimer’s Disease.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #BrainImaging #Neuroimaging #NeuroMetabolism #AcetateHypermetabolism #GlucoseHypometabolism #NeuroInflammation #CognitiveDecline #CognitiveDysfunction

https://www.genengnews.com/topics/drug-discovery/imaging-study-implicates-neuron-interaction-in-ad-alzheimers-cognitive-decline/

#Covid19 #CognitiveDysfunction #pwDementia

"In addition to finding that that all subtypes of dementia, irrespective of patients’ previous dementia types, behaved like rapidly progressive dementia following COVID-19, the team of investigators found that the line of demarcation between different types of dementia became remarkably blurry post-COVID-19."

https://neurosciencenews.com/covid-19-dementia-22938/

🇬🇧The 23th of April or the 2nd of March? #worldbookday
Anyway, my diseases stolen me one of my passion due to #brainfog. But I'm stubborn and I started reading last year again: comics instead thick books.

Web view has a translator but you can read the post using other options from your device.

#239 La sirena a la que se le mojaron los libros (leer con #DisfuncionCognitiva) 🐺 https://domandoallobo.blogspot.com/2017/04/235-la-sirena-la-que-se-le-mojaron-los-libros.html
#Lupus #MyalgicEncephalomielitis #MEcfs #Sjögren #fibromyalgia #SAF #CognitiveDysfunction #blog

#CognitiveDysfunction #Myalgicencephalomyelitis #LongCovid #chronicillness

"For me, looking back at my life with mild ME/CFS and mild brain fog, I had many cognitive issues. The most stark of which was a pretty severe loss of long and short term memory. It was as if my past was starting to be wiped clean, I simply could not access my memories and was often drawing a blank when people referred to experiences we had together; I couldn’t remember them at all."

https://www.whitneydafoe.com/mecfs/?post=what-does-brain-fog-feel-like