#OpenSLS: #OpenSource #Arduino-controlled selective #laser #sintering of nylon & #biocompatible #polycaprolactone (PCL):

-potential to produce PCL scaffolds useful for cell studies

Paper: https://doi.org/10.1371/journal.pone.0147399
Web: https://andreasbastian.com/opensls
GitHub: https://github.com/MillerLabFTW/OpenSLS
#DIYbio #lab #3Dprinting #SLS #instruments

#OpenSource iron nitride permanent #magnets made with #DIY ball mill:
https://hackaday.com/2025/06/19/iron-nitride-permanent-magnets-made-with-diy-ball-mill/
#DIYbio #DIYchem #magnetism #magnet #materials #science #lab #instruments

#OpenIDS: An #OpenSource, #3Dprinted, #Arduino- & #RasPi-controlled inkjet #DNA #microarray synthesizer:

-phosphoramidite #chemistry
-Si wafer substrate
-#GUI control & #camera monitored

Paper: https://doi.org/10.1038/s41598-024-53944-x
GitHub: https://github.com/regiregire/OpenIDS
#DIYbio #DIYchem #lab #instruments #Python

#AlphaDesign: An #OpenSource de novo #protein #design framework based on #AlphaFold:
https://doi.org/10.1038/s44320-025-00119-z
#DIYbio #CompChem #bioinformatics #AF

#Altair-LSFM: A high-res, easy-to-build light-sheet #OpenSource #microscope for sub-cellular #imaging:

-lateral/axial res: ~235/350 nm across 266-µ FOV after deconvolution

Preprint: https://doi.org/10.1101/2025.04.08.647739
Repo: https://thedeanlab.github.io/altair/
#DIYbio #lab #instruments #microscopy #LSM #fluorescence

#FLUID: An #OpenSource #3Dprinted #Arduino-controlled #synthesis #robot - Hardware & software blueprints for accessible #automation in #materials #science:

#NOpenAccess paper: https://doi.org/10.1021/acsaenm.5c00084
#DIYbio #DIYchem #chemistry #lab #instruments

An #OpenSource, low-cost multinuclear #NMR #spectrometer operating in the mT field regime:

-high spectral resolution
-arbitrary #RF pulse programming
-requires #LabVIEW
-cost: k$ 20 (mainly PXI waveform generator & digitizer alone)
-cost could be driven down by half using a home-built RF amplifier made with high-power operational amplifiers

#NOpenAccess paper: https://doi.org/10.1016/j.jmr.2021.107076
#DIYbio #DIYchem #chemistry #analytics #ULF #spectroscopy

#Microscope Upcycling: Transforming legacy microscopes into #automated #cloud-integrated #imaging systems:

-#OpenSource automation: X-Y positioning, focus stacking, image acquisition/storage
- cost: US $300

https://doi.org/10.1016/j.ohx.2025.e00637
#DIYbio #lab #instruments #microscopy #Raspi #PiCam #Python #OpenCV #StreamDeck #GUI

Printed, decoupled dual-loop #OpenSource #magnetic field #sniffer probe for bench measurements on radio frequency #MRI coils:

-cost: US $3

https://doi.org/10.1016/j.ohx.2025.e00659
#DIYbio #DIYchem #chemistry #lab #instruments #RF #MR

I'll be in LA next week, from 18th to 22nd. If anyone in the area wants to chat about #diybio #amateurscience #independentresearch please feel free to drop a note!

Designing & building a low-cost portable #OpenSource FT-NMR #spectrometer:
https://doi.org/10.1016/j.crci.2019.07.001
#DIYbio #DIYchem #chemistry #lab #instruments #NMR #spectroscopy

#cNMR: #OpenSource compact time-domain hydrogen (1H) #NMR system for field deployment:

-based on a 0.5 T permanent magnet
-emphasizes relaxation times rather than chemical shifts, enabling material property analysis without large magnets or complex spectral processing
-requires #LabVIEW

Paper: https://doi.org/10.1016/j.ohx.2025.e00651
GitHub: https://github.com/ARTS-Laboratory/Compact-NMR
#DIYbio #DIYchem #chemistry #lab #instruments

Low-cost #3Dprinted #OpenSource loading stage with an integrated mask system for versatile selective sample deposition on in situ liquid cell #transmission #electron #microscopy (#TEM) chips:

https://doi.org/10.1016/j.ohx.2025.e00663
#DIYbio #lab #instruments #chemistry #imaging #EM #MEMS #NanoTech

A portable low-cost #Arduino-controlled #OpenSource #polymerase chain reaction device:

-4-well aluminum heating block
-heated lid
-heating/cooling rates: 1.78/1.52 °C/s
- temp. accuracy: ± 0.55 °C
-cost: US $120
-requires #MATLAB

https://doi.org/10.1016/j.ohx.2025.e00635
#DIYbio #lab #instruments #PCR #DNA

The 35mm screening of the original blade runner is still running in my mind.

Long ago, bunch of us rented out a decrepit warehouse in Brooklyn, setup a lab and cloned heavy metal sequestering genes to produce quantum dots. Used to get cheap 6 packs and play blade runner on a projector in the background. Rain leaking through ceiling. This was before most even knew what synthetic biology was.

Many people from these days turned out to be, or turned into scumbags. I wonder what happened #diybio

A few images from yesterdays first #HoloDeck presentation at Prof. Varshneys #lab at the #Indian Institute of #Science (#IISc) in #Bangalore (#India), where people enjoyed 'playing molecules'.

Holodeck, also known as the Rechenkraft.net #Molecular #AR Environment is our #OpenSource approach - based on the @tiltfive hardware - to visualize molecular #structures in #3D for #education & #research & #development purposes.

#DIYbio #instruments #bioinformatics #CompChem #AugmentedReality #STEM #MINT

6/n If you want to support our work, you could become part of our #community efforts by a Rechenkraft.net #charity #membership and add your ideas to ours. ;-)
#DIYbio #lab #instruments #OpenSource #chemistry #bioinformatics #CompChem #AugmentedReality #MINT #Schule #Lehre #STEM #education #TiltFive

5/n We are also in close contact with #Richtsbergschule in #Marburg where #HoloDeck will be used in #biology & #chemistry #teaching #classes using @tiltfive hardware, soon.
#DIYbio #lab #instruments #OpenSource #chemistry #bioinformatics #CompChem #AugmentedReality #MINT #STEM #education

4/n In February this year, we got funded (as #HoloDeck project) by #JLU / #HMWK / #HessenHub to develop a #university #course to teach #students & #educators how to construct #molecular materials for this #AR platform.
#DIYbio #lab #OpenSource #chemistry #bioinformatics #AugmentedReality #STEM #MINT

2/n While our #IdeenExpo presentation from last year just covered #Windows OS, this time we presented the #AR molecular visualization system running under #Ubuntu 24.04LTS #Linux. Lots of fun explaining...
#DIYbio #lab #instruments #OpenSource #chemistry #bioinformatics #CompChem #AugmentedReality